泡罩包裝機(jī)論文

1、.1摘 要LBP-250滾筒式泡罩包裝機(jī)廣泛應(yīng)用于輕工、醫(yī)藥和化工行業(yè)，特別是藥品包裝。雖然我國的滾筒式泡罩包裝有了很大的開展，但是在產(chǎn)品開發(fā)、性能、質(zhì)量、可靠性、價格、效勞等方面在與進(jìn)口產(chǎn)品的競爭中處于劣勢。因此，很有必要對滾筒式泡罩包裝機(jī)深入研究，對其機(jī)構(gòu)、原理、運(yùn)動、功能進(jìn)展研究分析，提供構(gòu)造簡單可靠、操作方便、自動化程度高、應(yīng)用圍廣的滾筒式泡罩包裝機(jī)。設(shè)計(jì)容主要分為四大局部：第一，系統(tǒng)地分析滾筒式泡罩包裝機(jī)的根本構(gòu)造和和工作原理，全面分析包裝機(jī)的工藝路線，得出傳動方案；第二，通過工作原里論述分析,對槽輪機(jī)構(gòu)、熱封合機(jī)構(gòu)、動力步進(jìn)機(jī)構(gòu),得出各構(gòu)造件的參數(shù)；第三，通過數(shù)學(xué)建模，采用圖解法,

2、對運(yùn)動機(jī)構(gòu)進(jìn)展力學(xué)和運(yùn)動學(xué)分析校核；第四，根據(jù)前面所推導(dǎo)的理論，確定整體方案，根據(jù)設(shè)計(jì)所得到的尺寸完成總裝配圖和其他零件圖紙。關(guān)鍵詞：泡罩包裝；成型；熱封合AbstractLBP-250 flat blister packaging machine is widely used in light industry, medicine and chemical industries, especially pharmaceutical packaging. Although Chinas Flat blister packaging has a great development, it is

3、disadvantage in the petition in product development, performance, quality, reliability, price, service and other areas in and imported products. Therefore, it is necessary to Flat blister packaging machine-depth study of its institutions, principles, sports, research and analysis functions, to provi

4、de simple and reliable, easy to operate, a high degree of automation and wide application of the Flat blister packaging machine.The design elements are divided into four parts: First, the systematic analysis of Flat blister packaging machine and the basic structure and working principle, a prehensiv

5、e analysis of the packaging machine line that drive the plan; Second, through the work of the e*position, Analysis of the reducer, the institutions of heat-seal gathers, power step, electrical control design, that the structure of the parameters ;Third, through mathematical modeling, using graphic m

6、ethod, sports bodies and the mechanics of kinematics Checking; Fourth, according to previously deduced theory, determine the overall plan, according to the size of the design be pleted by the general assembly and other parts drawings. Key words：Blister packaging; Plastic molding;Hot sealing目 錄 TOC o

7、 1-3 f h z HYPERLINK l _Toc462046421第1章 緒論 PAGEREF _Toc462046421 h 1HYPERLINK l _Toc4620464221.1 概述 PAGEREF _Toc462046422 h 1HYPERLINK l _Toc4620464231.2 研究意義 PAGEREF _Toc462046423 h 1HYPERLINK l _Toc462046424第2章 LBP-250泡罩包裝機(jī)的方案設(shè)計(jì) PAGEREF _Toc462046424 h 2HYPERLINK l _Toc4620464252.1 設(shè)計(jì)任務(wù)分析 PAGEREF

8、_Toc462046425 h 2HYPERLINK l _Toc462046426設(shè)計(jì)參數(shù) PAGEREF _Toc462046426 h 2HYPERLINK l _Toc462046427工藝路線 PAGEREF _Toc462046427 h 2HYPERLINK l _Toc462046428主要參數(shù)確實(shí)定 PAGEREF _Toc462046428 h 2HYPERLINK l _Toc4620464292.2 功能分析 PAGEREF _Toc462046429 h 3HYPERLINK l _Toc462046430總功能確實(shí)定 PAGEREF _Toc462046430 h

9、3HYPERLINK l _Toc462046431設(shè)計(jì)任務(wù)抽象化 PAGEREF _Toc462046431 h 3HYPERLINK l _Toc462046432功能分解 PAGEREF _Toc462046432 h 3HYPERLINK l _Toc462046433功能構(gòu)造確定PAGEREF _Toc462046433 h 4HYPERLINK l _Toc4620464342.3 功能分解 PAGEREF _Toc462046434 h 4HYPERLINK l _Toc462046435分功能原理解 PAGEREF _Toc462046435 h 4HYPERLINK l _T

10、oc462046436系統(tǒng)方案求解 PAGEREF _Toc462046436 h 4HYPERLINK l _Toc4620464372.4 方案評價 PAGEREF _Toc462046437 h 5HYPERLINK l _Toc4620464382.5 系統(tǒng)方案原理圖 PAGEREF _Toc462046438 h 5HYPERLINK l _Toc462046439第3章 傳動系統(tǒng)設(shè)計(jì)計(jì)算 PAGEREF _Toc462046439 h 8HYPERLINK l _Toc4620464403.1 電動機(jī)選擇 PAGEREF _Toc462046440 h 8HYPERLINK l _

11、Toc4620464413.2 傳動比分配 PAGEREF _Toc462046441 h 8HYPERLINK l _Toc4620464423.3 各軸功率、轉(zhuǎn)速及轉(zhuǎn)矩設(shè)計(jì)計(jì)算 PAGEREF _Toc462046442 h 8HYPERLINK l _Toc4620464433.4 傳動零件的設(shè)計(jì)計(jì)算 PAGEREF _Toc462046443 h 10HYPERLINK l _Toc462046444 帶傳動設(shè)計(jì)計(jì)算 PAGEREF _Toc462046444 h 10HYPERLINK l _Toc462046445 齒輪傳動設(shè)計(jì)計(jì)算 PAGEREF _Toc462046445 h

12、12HYPERLINK l _Toc462046446 鏈傳動設(shè)計(jì)計(jì)算PAGEREF _Toc462046446 h 15HYPERLINK l _Toc462046447 軸的設(shè)計(jì)計(jì)算 PAGEREF _Toc462046447 h 16HYPERLINK l _Toc462046448滾動軸承壽命計(jì)算 PAGEREF _Toc462046448 h 20HYPERLINK l _Toc462046449第4章 執(zhí)行系統(tǒng)設(shè)計(jì)計(jì)算 PAGEREF _Toc462046449 h 21HYPERLINK l _Toc4620464504.1 成型機(jī)構(gòu)運(yùn)動與動力分析 PAGEREF _Toc462

13、046450 h 21HYPERLINK l _Toc4620464514.2 封合機(jī)構(gòu)運(yùn)動與動力分析 PAGEREF _Toc462046451 h 21HYPERLINK l _Toc4620464524.3 輥式泡罩包裝機(jī)的工作循環(huán)圖 PAGEREF _Toc462046452 h 22HYPERLINK l _Toc4620464534.4 典型零部件構(gòu)造設(shè)計(jì) PAGEREF _Toc462046453 h 23HYPERLINK l _Toc4620464544.4.1成型輥構(gòu)造設(shè)計(jì) PAGEREF _Toc462046454 h 23HYPERLINK l _Toc46204645

14、54.4.2封合輥構(gòu)造設(shè)計(jì) PAGEREF _Toc462046455 h 23HYPERLINK l _Toc462046456第5章 控制系統(tǒng)設(shè)計(jì) PAGEREF _Toc462046456 h 25HYPERLINK l _Toc4620464575.1 選擇控制器 PAGEREF _Toc462046457 h 25HYPERLINK l _Toc4620464585.2 選擇PLC PAGEREF _Toc462046458 h 25HYPERLINK l _Toc4620464595.3 選擇傳感器 PAGEREF _Toc462046459 h 26HYPERLINK l _To

15、c4620464605.4程序流程 PAGEREF _Toc462046460 h 27HYPERLINK l _Toc4620464615.5硬件電路的設(shè)計(jì) PAGEREF _Toc462046461 h 28HYPERLINK l _Toc462046462畢業(yè)論文總結(jié) PAGEREF _Toc462046462 h 30HYPERLINK l _Toc462046463參考文獻(xiàn) PAGEREF _Toc462046463 h 30HYPERLINK l _Toc462046465致 PAGEREF _Toc462046465 h 32HYPERLINK l _Toc462046466附錄

16、英文原文 PAGEREF _Toc462046466 h 33HYPERLINK l _Toc462046467附錄中文翻譯 PAGEREF _Toc462046467 h 37HYPERLINK l _Toc462046468附錄程序清單 PAGEREF _Toc462046468 h 39.1緒 論概述本次畢業(yè)設(shè)計(jì)的題目是LBP-250泡罩包裝機(jī)成型熱封系統(tǒng)設(shè)計(jì)，這個題目是在九天制藥及春光包裝機(jī)械參觀后決定的。本包裝機(jī)主要是進(jìn)展顆粒料，例如膠囊進(jìn)展包裝。整個工作流程可分為藥品填充、熱塑薄膜成型、熱塑薄膜與覆蓋鋁箔的密封、打碼及沖裁四個局部。由于設(shè)計(jì)時間有限，本次只進(jìn)展成型及熱封合的設(shè)計(jì)。其

17、中成型采用吸塑成型，熱封采用熱壓封合。整個控制局部采用PLC控制，主要是對成型溫度、熱封溫度，及電機(jī)的控制。PLC是根據(jù)用戶需要來選擇相應(yīng)的模塊，用戶程序在系統(tǒng)程序上運(yùn)行和編制。正是其在系統(tǒng)運(yùn)行時擁有諸多優(yōu)點(diǎn)，使得技術(shù)人員與廣闊企業(yè)設(shè)備商在進(jìn)展控制器選擇時優(yōu)先選擇PLC作為系統(tǒng)設(shè)計(jì)的首選控制器。所以在此次設(shè)計(jì)中使用PLC作為本設(shè)備的控制模塊。研究意義藥用泡罩包裝機(jī)是一種用來包裝口服固體藥片的包裝機(jī)器。塑料硬片的加熱、成型等諸多操作往往都是在同一個藥用泡罩包裝機(jī)上完成的。為了使人們能夠更好的了解此類機(jī)械設(shè)備，筆者將此類系統(tǒng)設(shè)備具有的優(yōu)勢進(jìn)展了以下總結(jié)闡述：1、泡罩包裝具有良好的阻隔性。此類設(shè)備之

18、所以具有良好的阻隔性主要是由原材料自身的包裝決定的。通過與瓶裝藥品的比照可以看出，藥品經(jīng)過泡罩包裝之后能夠有效減少要求的污染且便于患者隨身進(jìn)展藥品攜帶，同時經(jīng)過泡罩包裝之后，藥片在相氣體阻隔性、透濕性等諸多方面也具有明顯的優(yōu)勢。 2、此類包裝的另一優(yōu)勢在于藥品包裝的平安性。藥品在采用泡罩包裝時整個過程是一氣呵成的，在包裝過程未完成之前，其藥片包裝不會完畢。通過泡罩包裝在進(jìn)展藥品包裝之前會對藥品進(jìn)展多種平安檢測，從根本上保證了包裝的平安性和衛(wèi)生性，使藥品誤裝現(xiàn)象降到最低。 LBP-250泡罩包裝機(jī)的方案設(shè)計(jì)設(shè)計(jì)任務(wù)分析泡罩包裝機(jī)是一種廣泛用于片劑、膠囊等藥品及食品的包裝的包裝類機(jī)械，泡罩包裝機(jī)按

19、照封合方式不同，可以將其劃分為成型和熱壓兩類封合方式，且兩類方式都具有滾筒式和平板式兩類包裝方法。設(shè)計(jì)參數(shù)使用藥品規(guī)格：平素片：20*6mm； 膠 囊：0號-3號； 糖衣片：10,說明此類軸承是合格的。執(zhí)行系統(tǒng)設(shè)計(jì)計(jì)算成型機(jī)構(gòu)運(yùn)動與動力分析成型采用輥式成型，成型輥在齒輪的帶動下作勻速轉(zhuǎn)動，成型過程中成型輥部用冷水進(jìn)展冷卻，成型輥四周分布多個吸氣通道，如圖4.1所示。成型輥圖4.1成形機(jī)構(gòu)成型輥轉(zhuǎn)速：r/min成型輥直徑：153mm成型輥寬：140mm成型輥一周均勻分布六板泡罩模型。封合機(jī)構(gòu)運(yùn)動與動力分析PVC硬片與鋁箔封合時，需將兩種材料壓緊。當(dāng)機(jī)器處于工作狀態(tài)時，采用網(wǎng)紋輥依靠彈簧的壓緊力與

20、成型輥壓合在一起，實(shí)現(xiàn)封合。當(dāng)更換PVC時需要將兩輥分開，本方案采用杠桿機(jī)構(gòu)實(shí)現(xiàn)此功能，如圖4.2所示。封合輥通過加熱管進(jìn)展加熱，封合輥的封合壓力由四個彈簧提供。封合壓力：F=42N48N封合溫度：封合輥開合移動的距離根據(jù)構(gòu)造選定：L12mm封合輥直徑：d=120mm封合輥寬：140mm封合輥圖4.2封合輥開合機(jī)構(gòu)輥式泡罩包裝機(jī)的工作循環(huán)圖打印沖裁牽引封合上料成型加熱圖4.3工作循環(huán)圖典型零部件構(gòu)造設(shè)計(jì)成型輥構(gòu)造設(shè)計(jì)圖4.4成型輥構(gòu)造圖如圖4.4所示，成型輥轉(zhuǎn)速n=r/min，根據(jù)所定生產(chǎn)率推出成型輥一周均勻分布6板泡罩模型，為了提高生產(chǎn)率將成型輥的泡罩加工成并排兩板，成型輥部中空，運(yùn)行過程中

21、可通過冷水進(jìn)展冷卻降溫，沿圓周方向均勻分布30個吸氣孔，氣孔直徑d=10mm。泡罩規(guī)格：80mm57mm8mm,由泡罩規(guī)格可知成型輥直徑d=153mm，寬L取140mm，成型輥?zhàn)蠖思庸せㄦI槽，尺寸如下列圖。成型輥材料：硬鋁封合輥構(gòu)造設(shè)計(jì)圖4.5封合輥構(gòu)造圖如圖4.5所示，封合輥部采用中空構(gòu)造，這樣可以有效防止運(yùn)行過程中產(chǎn)生的熱量直接傳遞到主軸，防止因發(fā)熱而影響主軸正常運(yùn)轉(zhuǎn)。封合輥兩端設(shè)有支架，通過螺栓連接到封合輥，使用鍵連接的方式將其與主軸連接在一起。封合輥外徑由構(gòu)造定位D=120mm，寬L=140mm，徑d=57mm。封合輥沿軸向均勻分布6各加熱管，封合溫度：150160?？刂葡到y(tǒng)設(shè)計(jì)選擇控

22、制器在本包裝機(jī)熱封系統(tǒng)設(shè)計(jì)中，控制器是必不可少的局部。而現(xiàn)如今在企業(yè)中被泛使用的有：PLC可編程控制器51系列單片機(jī)，PIC單片機(jī)等。雖然PLC中沒有相關(guān)的繼電器設(shè)備，但其可以通過程序運(yùn)行以及系統(tǒng)其它功能來彌補(bǔ)繼電器缺失的缺乏。PLC硬件安裝簡單，組裝容易。外部接線有接線器，接線簡單，而且一次接好后，更換模塊時，把接線器安裝到新模塊上即可，都不必再接線。PLC工作可靠，出現(xiàn)故障的情況不多，這大大減輕了維修的工作量。PLC的外設(shè)很豐富，編程器種類很多，用起來都較方便，還有數(shù)據(jù)監(jiān)控器，可監(jiān)控PLC的工作。同時兼?zhèn)洹皵?shù)字量或模擬量輸入/輸出控制的能力。所以說PLC是工業(yè)企業(yè)控制的理想控制器，因而在本

23、次設(shè)計(jì)中使用PLC作為LPB-250的控制器。選擇PLCLBP-250包裝機(jī)在控制過程需要接收溫度傳感器的模擬量，所以選擇使用德國西門子生產(chǎn)的S7-200型PLC，CPU為224*P。S7-200型PLC自帶14路數(shù)字量輸入10路數(shù)字量輸出和2路模擬量輸入和1路模擬量輸出輸入口，6路高速計(jì)數(shù)器，雙向輸入。2個高速脈沖輸出，每路20KHZ，0.75A電流。2個10位輸入0V10V。1路10位輸出，032767對應(yīng)010V和020mA帶擴(kuò)展口，支持西門子原裝模塊及第三方功能同西門子原裝模塊的模塊。輸入4V電源不分正負(fù)方向，可有有效防止接錯電源燒毀PLC的情況。并且此類包裝機(jī)還增加了諸多功能，新興的

24、CPU具有大量的模擬量I/O和強(qiáng)大的控制能力。 圖5.1 CPU 224 *P本體集成的模擬量I/O接線圖 選擇傳感器本包裝機(jī)需要兩個溫度傳感器，經(jīng)網(wǎng)上查閱決定選用PT100貼片式溫度傳感器，具體型號為WZP100TTP。WZP-PT100溫度傳感器是由三局部組成。不同的局部在傳感器當(dāng)中起到的作用也是各不一樣。此類型號的溫度傳感器之所以采用航插接頭，主要是為了方便信號線的信號輸入傳遞，同時在出現(xiàn)故障時，也能方便管理人員更好的進(jìn)展障礙排除以及器件維修。此外，采用直接插拔的方式能夠方便器件之間的直接連接，減少用戶由于接線錯誤造成的虧損。此外，貼片式溫度傳感器與被測物體之間存在較大的未接觸面積，使得

25、其在進(jìn)展外表溫度測量方面相對其他溫度傳感器來講存在較大優(yōu)勢。圖5.2 WZP100TTP外形及參數(shù)5.4程序流程 圖5.3 程序流程圖設(shè)備開場運(yùn)行時，系統(tǒng)進(jìn)展初始化，初始化完成時，按下啟動按鈕，加熱指示燈亮，同時加熱輥和熱封輥加熱，溫度分別同時到達(dá)130和160時停頓加熱，電動機(jī)啟動，工作指示燈亮成型輥開場注入冷水，起到冷卻降溫作用。當(dāng)加熱輥溫度低于120時，則加熱輥繼續(xù)加熱，到達(dá)130是停頓加熱。同理，熱封輥溫度低于150時，繼續(xù)加熱，到達(dá)160停頓加熱。滿足以上條件，設(shè)備開場正常工作。5.5硬件電路的設(shè)計(jì)圖5.4 控制系統(tǒng)硬件電路圖圖5.6 輸入元件地址分配表圖5.7 輸出原件地址分配表畢

26、業(yè)論文總結(jié)在本次畢業(yè)論文完成之計(jì)，本人大學(xué)四年學(xué)習(xí)生涯即將完畢?；厥兆约核哪甑拇髮W(xué)生活，想想四年接觸過的人、事即將進(jìn)展離開這片土地，本人會校園生活產(chǎn)生無限眷戀。通過本次畢業(yè)論文設(shè)計(jì)，筆者能夠運(yùn)用自己所學(xué)的專業(yè)知識進(jìn)展畢業(yè)設(shè)計(jì)，但由于本人自身的水平有限，以及調(diào)查研究設(shè)備簡陋，使得局部調(diào)查研究未能到達(dá)預(yù)期效果。通過教師指導(dǎo)并結(jié)合自身的專業(yè)所學(xué)，本人最終選擇了“滾筒式泡罩包裝機(jī)封合系統(tǒng)設(shè)計(jì)這篇論文進(jìn)展文章編寫，在確定了論文題目之后，筆者通過查閱大量的研究資料以及相關(guān)理論文獻(xiàn)，開展本次畢業(yè)論文設(shè)計(jì)。雖然在本次畢業(yè)論文設(shè)計(jì)期間遇到較大的阻礙，但在教師的耐心指導(dǎo)和幫助之下，本次畢業(yè)論文最終順利完成。經(jīng)過幾

27、個月的學(xué)習(xí)編寫，本次畢業(yè)論文最終完成?；厥鬃陨碚麄€畢業(yè)論文編寫過程，其中經(jīng)歷的心酸和苦難只有自身能夠切身感受。雖然整個畢業(yè)論文設(shè)計(jì)的過程是非常辛苦的，但最終的畢業(yè)成果讓本人覺得一切付出都是值得的。通過畢業(yè)論文的編寫也是筆者對所學(xué)知識的重新學(xué)習(xí)，將自身所學(xué)的專業(yè)知識得到真正的實(shí)踐應(yīng)用。在進(jìn)展畢業(yè)設(shè)計(jì)期間，本人煤炭都沉浸在知識的海洋當(dāng)中，在進(jìn)展公式查找以及資料查詢的過程雖然枯燥無昧，但本人卻充滿干勁，雖然威力能夠在規(guī)定時間完本錢次論文設(shè)計(jì)，往往熬到深夜才能入睡，但在進(jìn)展畢業(yè)設(shè)計(jì)過程中本人卻學(xué)到了之前沒有學(xué)到的知識和精神，充實(shí)了自己專業(yè)知識的同時，表到達(dá)了堅(jiān)持、永不放棄精神的可貴。此外，諸多同學(xué)也在

28、本人進(jìn)展畢業(yè)論文編寫時給予本人支持和鼓勵，讓筆者始終充滿繼續(xù)研究的根本動力。同時，整個畢業(yè)論文能夠順利完成，離不開指導(dǎo)導(dǎo)師以及專業(yè)教師對我的幫助。本人在進(jìn)展畢業(yè)設(shè)計(jì)時遇到的諸多問題都是在教師的幫助指導(dǎo)之下得到充分解決。同時教師們認(rèn)真復(fù)雜、無私奉獻(xiàn)的精神也給本人留下了深刻的印象。通過本次畢業(yè)論文編寫，不僅能夠提高自身的專業(yè)知識，也會學(xué)會做人的道理。筆者謹(jǐn)以此文向那些幫助過我的教師、學(xué)長表示中心的感。參考文獻(xiàn)1 鄧茂云.機(jī)械設(shè)計(jì)根底M.：西南交通大學(xué)，2021.10.2賢武.機(jī)械設(shè)計(jì)根底課程設(shè)計(jì).：華中科技大學(xué)，2021.1.3吳宗澤.機(jī)械設(shè)計(jì)實(shí)用手冊.：化工工業(yè)，2021.4.4鞏云鵬.機(jī)械設(shè)計(jì)

29、課程設(shè)計(jì)M.：東北大學(xué)，2021 .12.5賈伯年.傳感器技術(shù)M.：東南大學(xué)，2021.9.6遠(yuǎn)齡.機(jī)床電氣自動控制M.：大學(xué)，2021.8.7聞邦椿.機(jī)械設(shè)計(jì)手冊. ：機(jī)械工業(yè)，2021.1.8魯遠(yuǎn)棟.PLC機(jī)電控制系統(tǒng)應(yīng)用設(shè)計(jì)技術(shù).： 電子工業(yè)，2021.3.9 吳紅霞.電氣控制與PLC原理及應(yīng)用M.：冶金工業(yè)，2021.9.10周四六.可編程控制器根底及編程技巧M.:人民郵電,2021.6 .11左健民.液壓與氣壓傳動M.：機(jī)械工業(yè),2007.5.12國全.包裝機(jī)械設(shè)計(jì) M.：文化開展, 2021.2.13良渠，杜力.包裝機(jī)械原理與設(shè)計(jì).西南交通大學(xué)，2021.9.14 Collins,

30、 Jack A.Mechanical Design of Machine Elements and Machines Collins. 美國.John Wiley & Sons，2021.10.15希格利. 機(jī)械工程設(shè)計(jì)英文版.原書第6版.美國.機(jī)械工業(yè)2021.3.致 經(jīng)過本人的不懈努力，本次畢業(yè)設(shè)計(jì)最終順利完成。畢業(yè)設(shè)計(jì)期間得到了紅梅教師和其他教師大力幫助，他們每個人都盡職盡責(zé)，當(dāng)我們有不懂得問題時教師總是給我們認(rèn)真講解指導(dǎo)，直到我們明白為止，教師們總是在我們需要幫助的時候伸出他們溫暖的手幫我們走出困境，真的很感他們，是他們的辛勤栽培才有了今天的我們；在這幾個月中自己真的學(xué)到了許多，通過畢

31、業(yè)設(shè)計(jì)自己以前學(xué)到的知識得到了穩(wěn)固。本文論文在進(jìn)展設(shè)計(jì)之初，紅梅教師從論文的選題、方案的制定以及容的調(diào)查等諸多方面對我的耐心指導(dǎo)以及詳細(xì)講解，同時本人在本科學(xué)習(xí)階段的四年來各位教師認(rèn)真教學(xué)的態(tài)度以及誠信守信的形象給我留下了深刻的印象，同時在本文今后的工作學(xué)習(xí)中，紅梅教師的工作態(tài)度對我今后的學(xué)習(xí)起到了至關(guān)重要的作用。在此，我也要向我院所有幫助我的教師以及同學(xué)表示感，在四年的時光中，教師和同學(xué)的幫助使得我在生活中各類不同的困難都得到了化解。同時在工業(yè)大學(xué)我也度過了四年的愉快時光。家人和朋友在我四年的學(xué)習(xí)中給予了我極大的支持和鼓勵，是本人完成學(xué)業(yè)最為堅(jiān)強(qiáng)的后盾。正是由于家人、朋友和教師對我的鼓勵和鞭

32、策,本人才能如此順利的完成自己的學(xué)習(xí)任務(wù)和學(xué)位論文的設(shè)計(jì)，在此本人謹(jǐn)以此文獻(xiàn)給所有關(guān)心和幫助過我的導(dǎo)師、領(lǐng)導(dǎo)、教師、同事、同學(xué)、朋友,以及始終給予我支持的父母和家人。附 錄 英文原文Blister Packaging MachineDrugs, also known as blister packaging blister packaging eyes, or PTP (Press ThroughPackaging) packaging technology, developed rapidly in recent years one of the forms of drug packagin

33、g. PTP technology is heated to soften the plastic sheet and placed inside the mold, or blow pressed air through the vacuum pump so that the method of forming, after the blisters into the eyes of medicine, and then coated with adhesive aluminum foil medicinal a certain temperature, pressure sealing u

34、nder conditions to form the blister packaging. At present, the pharmaceutical blister packaging has bee tablets, capsules, pills and other solid dosage forms the mainstream of packaging, the development momentum will continue. 1. Blister Packaging in China the status of drugs With the deepening of C

35、hinas reform and opening up and reform the health care system, especially after Chinas accession to the WTO, the international pharmaceutical panies more access to China, intensified petition in the pharmaceutical industry in China, but also increased the skill level of the industry as a whole and q

36、uality, which led to the development of pharmaceutical packaging, pharmaceutical packaging made in China is being the field of packaging with high technical content, significant benefits are very active branch, including solid dosage forms drugs also continues to introduce new packaging. At present,

37、 the worlds top 100 pharmaceutical panies in China, almost all of the establishment of joint ventures or wholly-owned pharmaceutical panies, not only brings more drug products, but also advanced the concept of pharmaceutical packaging and standards, but also to the form of drugs brought about by the

38、 diversification of the packaging. Chinas pharmaceutical packaging blister forms in recent years fast development, the structure is simple, fast heat sealing equipment, increasing demand and the emergence of a wide range of choices, including to meet the FDA requirements to the intelligent robot bas

39、ed on aluminum packaging systems; as well as many small and difficult to package products provide an effective solution. Pharmaceutical blister packaging materials in the past in our country relies mainly on imports, and to the present, with aluminum foil and blister packaging blister materials have

40、 been made, and to meet the needs of the domestic pharmaceutical packaging; made into the development of matri* vesicles gradually the formation of series, from the most widely used hard PVC films, PVDC coated films and the cold aluminum-plastic pound sheet molding posite materials, etc.; PTP also f

41、rom aluminum foil or double-sided single-sided printing blank variety, the development of single-sided or double-sided gold series, single-sided or double-sided color color series, two-sided printing monochrome or multicolor overprint varieties of dozens of series, and hard-PTP aluminum foil, there

42、are soft PTP aluminum foil, so that the bubble Drugs may choose to cover more of the packaging. However, pharmaceutical products in China the level of the blister packaging pared with the developed countries there is a big gap between the overall, the gap es down to the following reasons. 1) the ove

43、rall level of Chinas pharmaceutical industry is relatively low, traditional Chinese medicine production enterprises outdated technology has constrained the development of products and their packaging. 2) Drugs larger single dose, making the unit cost of blister packaging is still significantly highe

44、r than those bottle-type packaging, blister packaging hampered in the field of pharmaceutical packaging in China to promote the application (although the drug controlled release pharmaceutical sustained-release technology in our country applications, greatly reducing the dose of drugs, but not a rad

45、ical improvement in the pharmaceutical packaging blister packaging cost disadvantage. 3) drug distribution system of the disadvantages of long-term drug sales in the main hospital, there is no prescription of sub-and non-prescription, drugs at the pharmacy sales account for only a small part of the

46、total, this system also restricted the sale of pharmaceutical blister packaging development. 4) Chinas pharmaceutical packaging equipment, automation and can not catch up with the world advanced level in the development of blister packaging, blister packaging makes the promotion of drugs obviously l

47、agging behind the pace of advanced countries in the world; therefore, still have to package the level of advanced countries to learn, remember pharmaceutical blister packaging with the world trend. 2. Chinas drug development direction of Blister Packaging Organization of the United Kingdom market, a

48、ccording to newly released information on the European pharmaceutical packaging market research, in subsequent years, manufacturers of active pharmaceutical packaging may have a significant change in focus, in particular, will shift to blister packaging containers cardboard bo*es and packaging. Ther

49、efore, the ne*t 5 years, Chinas pharmaceutical blister packaging in process, packaging materials and production equipment and other aspects still need further efforts to faster development of pharmaceuticals blister packaging to further enhance the quality of Chinas pharmaceutical packaging and qual

50、ity of service, and with the rest of the world. 1) fully and effectively protect the drugs. Like with any form of packaging to protect the drugs, ensure the effectiveness of drugs is still the basic requirements for blister packaging. 2) Use the safety and convenience. Development suitable for the s

51、afety of the child-friendly packaging and packaging to facilitate the elderly. 3) a unique anti-counterfeiting packaging. Use of new technologies to achieve the diversification of blister packaging materials security, not only reflect the personality of drug packaging, but also the protection of ent

52、erprises and brand products. 4) green environmentally-friendly packaging. Vigorously the development and popularization of recyclable, biodegradable natural, do not pollute the atmosphere, such as the burning of new environment-friendly blister packaging, pharmaceutical packaging solution to the fun

53、damental aspects of the white pollution. 5) packaging and serialization. With the introduction of OTC pharmaceutical industry, the growing attention serialization packaging, blister packaging can be aluminum foil plate and the screen size changes of the elements to reach Series packaging, this packa

54、ging in the future development of drugs will also show their best. 6) the development of nano-blister packaging. Nano-technology and nano-materials applications in the field of medicine and the development of Chinas pharmaceutical blister packaging will provide a golden opportunity golden. 7) to ach

55、ieve high-barrier packaging. The rapid development of an e*cellent barrier blister packaging materials, pharmaceutical products in order to achieve high-barrier packaging, to ensure the effectiveness of drugs. 8) meet the OTC drug packaging. Blister Packaging with clearly defined and effectively sho

56、w the drugs easily available to patients, this will be the future production and distribution of OTC drugs can not be ignored during an important part. Pharmaceutical blister packaging has very obvious advantages, such as drug stability and reliability, less easy to measure and achieve serialization

57、 packaging, advanced technology, security, health, portable and easy to use, long shelf life, and have good adaptability and appearance and so on, so Throughout the ne*t few years, as drug packaging materials and packaging equipment constantly updated continuously improve performance, Chinas pharmac

58、eutical blister packaging design will be user-friendly, multi-function of the direction of development and environmental protection; in western medicine tablets, capsules, Chinese medicine The pill, powder, powder, particulate form, etc. will bee the mainstream of packaging; in Pharmaceutical Packaging will occupy an increasing share.附 錄 中文翻譯泡罩包裝機(jī)藥品泡罩包裝通常被稱作PTP包裝技術(shù)，隨著近幾年科技