Folinic-acid-Calcium-Leucovorin-Calcium-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFolinic acid CalciumCat. No.: HY-13664CAS No.: 1492-18-8Synonyms: Leucovorin Calcium; Calcium Folinate分式: CHCaNO分量: 511.5作靶點(diǎn): Antifolate作通路: Cell Cycle/DNA Damage儲存式: 4C, protect from light* 該產(chǎn)品在溶液狀態(tài)不穩(wěn)定，建議您現(xiàn)現(xiàn)配，即刻使。溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O

2、: 200 mg/mL (391.01 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.9550 mL 9.7752 mL 19.5503 mL5 mM 0.3910 mL 1.9550 mL 3.9101 mL10 mM 0.1955 mL 0.9775 mL 1.9550 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液；該產(chǎn)品在溶液狀態(tài)不穩(wěn)定，建議您現(xiàn)現(xiàn)配，即刻使。BIOLOGICAL ACTIVITY物活性 Leucovorin鈣鹽

3、是還原的葉酸。戶使本產(chǎn)品發(fā)表的科研獻(xiàn) J Mol Med (Berl). 2019 Jun 14.1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESee more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Schilsky RL, Ratain MJ. Clinical pharmacokinetics of high-dose leucovorin calcium after intravenous and oral administration. J NatlC

4、ancer Inst. 1990 Sep 5;82(17):1411-5.2. Chang WN, Tsai JN, Chen BH, Serine hydroxymethyltransferase isoforms are differentially inhibited by leucovorin: characterization andcomparison of recombinant zebrafish serine hydroxymethyltransferases. Drug Metab Dispos. 2007 Nov;35(11):2127-37.3. McGuire BW, Sia LL, Haynes JD, Absorption kinetics of orally administered leucovorin calcium. NCI Monogr. 1987;(5):47-56.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>