Kam 周鋒老師 醫(yī)學(xué)英語(yǔ)口語(yǔ)課 Pathogenesis of Anemia貧血發(fā)病機(jī)制

The

Pathogenesis

of

Anemia-貧血發(fā)病機(jī)制ClassA1Team22nd：LiuKunrong,Dalin,Rongxi(周峰老師英語(yǔ)課)ContentsDefinitionofAnemiaOnset&ProcessofAnemiainWM123ConclusionsDefinitionofAnemiaWhatdoesanemiamean?Anemiaisaconditioninwhichthenumberofredbloodcellsortheamountofhemoglobinintheperipheralcirculationislowerthanthenormalvalue.

ITheOnsetofanemiaTheOnsetofAnemia1、InadequateproductionofqualifiedRBC(紅細(xì)胞生成不足)Anemia2、ExcessivelossingordestructionofRBC(紅細(xì)胞損失過(guò)多)（1）InadequateProductionofQualifiedRBC1、LackingofmaterialsneededtomanufactureRBC

（造血原料不足）IronDeficientAnemia(IDA)(缺鐵性貧血)MegaloblasticAnemia(MA)(巨幼紅細(xì)胞性貧血)2、MaterialsneededtoproduceRBCcan’tbeusedinaproperway

（造血原料利用障礙）SideroblasticAnemia(SA)(鐵粒幼細(xì)胞性貧血)Atransferinemia(轉(zhuǎn)鐵蛋白缺乏癥)（1）InadequateProductionofQualifiedRBC3、DysfunctioninproducingenoughqualifiedRBC

（造血異常）AplasticAnemia(AA)(再生障礙性貧血)MyelodysplasticSyndrome(MDS)(骨髓增生異常綜合征)4、Decificiencyofhematopoieticcytokines

（促紅細(xì)胞生成素等因子不足）ChronicRenalInsufficiency(慢性腎功能不全或腎衰)Hypothyroidism(甲減)（2）ExcessiveLossing&DestructionofRBC1、MoreamountofRBCgoingoutofthevessels

（出血過(guò)多）Acutevesselinjuredwithexcessivebleeding(急性出血伴血容量丟失過(guò)多)Chronicbleeding(Tumourinjured,UC)(長(zhǎng)期出血)2、ExcessivedestructionofRBC（紅細(xì)胞破壞過(guò)多）HemolyticAnemia(HA)

(溶血性貧血)IITheProcessofanemiaTheProcessofAnemiaTissuesIINeurologicalsystemTissuesICardiovascularsystemRespiratorysystemDigestivesystemAnemiaTheProcessofAnemiaTheoriginalpathogenesis:

Oxygen-poorinalmostallthetissuesofthebody.（病機(jī)根源于組織缺氧）

（1）ManifestationsoftheNeurologicalSystem·Dizziness（頭暈）·Headache（頭痛）·Insomnia（失眠）（1）ManifestationsoftheNeurologicalSystemResultfromDizziness,headache,insomnia,hypomnesis,attentiondisorder,etc.Thereisn’tenoughRBCtotransmitadequateoxygentothenervoustissueswhichgraduallyleadstothesedysfunctionsintheneurocytes.(腦組織缺血缺氧)ManifestationsMechanism（2）ManifestationsoftheCardiopulmonarySystemLeadtoAhighrateofheartbeatingandbreathing,palpitation&shortnessofbreathafterexercises,etc.Mechanism·Inordertomaintainenoughoxygentransmittedtothevitalorgans&tissues,theheart&breathingratesareincreasedcompensatorily.(心肺代償)·Andthemyocardialwillbecomehypertrophyaftertheheartcompensatesforalongperiod.(心肌肥厚)Manifestations（2）ManifestationsoftheCardiopulmonarySystempalpitation（心悸）shortnessofbreathafterexercises（運(yùn)動(dòng)后氣短）（3）ManifestationsoftheDigestiveSystemLeadtoApoorappetite,dyspepsia,abdominalfullness,etc.Manifestations·Enzyme,whichisimportantfordigestion,willbeexcretedlesserthannormal.(消化酶分泌不足)·Digestiveglandswillevenwithergraduallyifthepatientsuffersfromanemiaforalongperiod.(消化腺萎縮)Mechanism（3）ManifestationsoftheDigestiveSystem·Apoorappetite（食欲不振）·Dyspepsia（消化不良）·Abdominalfullness（腹脹滿(mǎn)）（4）OtherManifestationsIMenstruationdisorder（月經(jīng)不調(diào)）somnolence&lassitude（嗜睡、疲憊）（4）OtherManifestationsIResultfromMenstruationdisorderTheendometriumgrowsslowlyduetotheRBC&oxygeninsufficiency.(子宮內(nèi)膜缺血缺氧)ManifestationsMechanismsomnolence&lassitudeRBC-poor&oxygen-poorinmostofthetissuesleadstoalowmetabolism&energydeficiency.(體內(nèi)能量代謝緩慢且不足)Resultfrom（5）OtherManifestationsIIDryskin（皮膚干燥）Salloworpalecomplexion（面色灰暗或蒼白）（5）OtherManifestationsIIResultfromDryhair,hairloss,dryskin,salloworpalecomplexion,palefingernails,lips&palpebralconjunctive,etc.Lessvolumeofbloodisofferedtotheskin&mucousmembraneswhilemoreblood&oxygenistransmittedtothevitalorgans&tissuesasthetotalquantityofRBCisn’tenough.(血液重新分配至重要組織器官致皮膚粘膜缺血)ManifestationsMechanismConclusionConclusionThewayspractitionersofTCMtrytoanalyseanemia

Notonlyfocusonthecauseofbloodinsufficiency,butalsoconcentrateonthedysfunctionthatthebodyproduceslessbloodthanbefore.(不僅想到血液不足，還關(guān)注到到使血液生成下降的原因)DoctorsofWMtrytolearnanemiainthesewaysPaymoreattentiontothetissuelikethebonemarrow,hematopoieticstemcellsandcytokinesthatcanmanufactureRBCandhowtheorganscanbeinjuredduringtheprocessofanemia.(更關(guān)心骨髓等是怎么造血的以及貧血是如何對(duì)氣管產(chǎn)生損害的)TreatmentsofTCM

Aimtoregularthebody’shematopoieticfunctionbyreplenishqi&nourishyin&blood,inwhichwaytheinjuredorgans&tissuescanberepaired.(調(diào)和氣血，修損復(fù)原)ConclusionDifferenttherapiescomefromdifferentmedicaltheories.(不同的醫(yī)學(xué)理論產(chǎn)生不同的對(duì)策)ConclusionDifferenttherapiescomefromdifferentmedicaltheories.TreatmentsofWM