應力調(diào)節(jié)對延長區(qū)骨愈合影響的實驗研究

1、檢測。結果操作檢測。結果操作結束后，兩組延長區(qū)骨痂X 線片表現(xiàn)不同：對照組延長區(qū) 】 牽張成骨；軸向應力；微動；骨延長；Influenceofstressregulationon bonehealingoflengthened zone:anexperimental study Hua qing,WANGKun zheng,ZHANGMing Yu,etal.Departmentof Orthopedics, the Second Hospital, Xian Jiaotong University, Xian 710004, ChinaAbstract：ObjectiveTo explore

2、 the effects of axial stress regulation on healing of lengthened callus.MethodTibiaes of 40 rabbits dividedo2groupswerelengthened with circular external fixator.X ray bone density and histology tests were performed.ResultThe X-ray showed lengthened callus was different after operation.hecontrol grou

3、p,lengthened center had a serial callus and cortex had not formed,heexperimental group lengthened center had serial cortex and ttransfixial medullaryexpects serial Axial stress regulation and periodicity continue to shortened micromovement stress may promote healing after bone lengthening.Keywords：d

4、istractionosteogenesis； axialstress；micromovement； bone lengthening； rabbits牽張成骨(isaonooneis,D)是由lrov在提出原1緩慢牽伸組織產(chǎn)一種應力可刺激些組織生和活躍長能夠動和促機體自身修復和生的潛能有效地療肢體等長等骨科疑難病但是體大幅延長后延長區(qū)的愈合需很長時間往往會患者帶針道的延遲合及長佩帶外固定器導的不舒感等問甚至導治療23，此，如促進延區(qū)骨愈合是臨迫切需解決骨延區(qū)的骨是一種特類型的愈合外施加的牽變了延區(qū)的微合的進成骨方式力負荷骨骼的構和骨量有著極重要的響4。者對應調(diào)節(jié)在脛骨延長骨愈合的作用行了實驗

5、研究，以察其對延長區(qū)愈合的用。節(jié),運用X 線檢查、光鏡觀察等【摘要】 1.2 1.2.1 3%戊巴比妥鈉(1mL/kg,iv)麻醉,左下肢去毛,下20mm 1.2 1.2.1 3%戊巴比妥鈉(1mL/kg,iv)麻醉,左下肢去毛,下20mm1.2mm克氏針 2枚克氏針相交角度(4050),230mm11mm4105u16萬u1.2.3 術后觀察 所有動物術后分籠飼養(yǎng),34105U8開始延長,1mm(2次完成,0.5mm)20mm20mm4d24mm （1）X線片 在延長結束時及處死動物后分別做X（2）骨密度測定 處死動物后)2（3）,5mm厚的薄片 1.3 SPSS8.0t2 結 果2.1 )

6、 ) 2.2 X 好 2)2.3 2.4 排 2.4 排1 對照組延長段骨痂X線片 圖2 實驗組延長段骨痂X3 痂組織(2.54) 4 實驗組延長段骨痂組織3 討 論牽張成骨(distractionosteogenesis,DO)是刺激骨形成的一種獨特方法，它使肢體延長技 / 1cm后,3d2mm,的原遞增 加壓。由于延長長度儲備有限(35mm左右),作用持續(xù)時間不長，如何使短縮加壓發(fā)揮20mm后繼續(xù)延長4mm作為儲備, 此后10行牽拉壓縮調(diào)節(jié)各2次, 調(diào)節(jié)幅度 1IlizarovGAthesyresseffectonesisandgrowthes.partinfluenceofstabili

7、tyoftherateandfrequenceofdistractionfixationandsoft presser vationJ.ClinOrthop1989,239:263-e2KocaogluM,EralpL,SenC,etal.Managementofstiffhypertrophicnonunionsdistractionosteogenesis:areportof16casesJ.JOrthopTrauma2003,8:543-3AntociV,OnoCM,AntociVJr,etal.Bonelengtheninginchildren:howtopredictcomplica

8、tionsrateandcomplexityJ.JPediatrOrthop2006,5:634-, , 5IlizarovGA.Transosseousosteosynthesis theoreticalandclinicalaspectsregenerationandgrowthofeJ.Berlin:Springer Verlag,1992,137-6KocaogluM,EralpL,SenC,etal.Managementofstiffhypertrophicnonunionsdistractionosteogenesis:ataleof16casesJ.JOrthopTrauma,2

9、003,17:543-7RheeST,anSR.Pediatricmandibulardistractionosteogenesis:theandthefutureJ.JCraniofacSurg,2003,14:803-8周 強，等. 脛骨截骨延長治療雙小腿不等長及身材矮小J.，,李 剛，等. 脛骨截骨延長治療雙小腿不等長及身材矮小J.，,李 剛13HamanishiC,YoshiT,TotaniY,etal.Lengthenedivatedbyshortening.Histologicalandcytomorph 14ColeJD,JustinD,KasparisT,etramedulla

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