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ConstructiveCaseNumber:ZM111711Customer:Dr.Manuscripttitle:脾切除加斷流術(shù)門脈高壓癥兔腸微生態(tài)狀況及微生態(tài)制劑的預(yù)研GeneralGeneralSummaryofThisThisstudyinvestigatedtheeffectsofmicrobialagentsonportalhypertensionmodelrabbitaftersplenectomywithdevascularization.Theauthorsused35rabbitsandsplitthemintogroups.And18post-operationsurvivorswerestudied.Accordingtotheauthors,microbialagentswerebeneficialtothepost-operationrabbits.First,thenumberofsurvivorrabbitsislimited,especiallyafterregrou.Thesignificanceofstatisticalysisbasedonthisnumberisnotveryconvincing.Second,thewaytheauthorsdidstatisticalysisrequiresimprovement.Isuggestthattheyshouldfindprofessionalassistance.這項(xiàng)研究探討了微生態(tài)制劑對(duì)脾切除加賁門周圍血管離斷門脈高壓兔模3518NoveltyandClinicalThenoveltyofthisstudyisgood,sincetherearenotalotsimilarreportsbeingpublishedrecently.Portalhypertensioniscommonlyseeninpatientswithliverdiseases.Thereforethedatainthismanuscriptmaybeusefulforthisgroupofpatients.Butthisstudyisbasedonrabbitmodel.Humanexperimentsarestillneededtovalidatetheresultshere.GrammarandEnglishTheentiremanuscriptisinChinese.AtleasttheauthorsneedtotranslatetheintoEnglish.整篇文章都是中文。作者至少需要將翻譯成英文Thiswillbeamajorjob.Alotofproblemswereobservedinthismanuscript.Manyoftheseproblemsmaydirectlyleadtorejection.MissingSeeotherOthersignificantcommentsareSpecificSpecificTitleThetitle脾切除加斷流術(shù)門脈高壓癥兔腸微生態(tài)狀況及微生態(tài)制劑的干預(yù)研究”generallyadequayconveysthecontentofthepaper.Thismanuscriptisabouttheeffectsofmicrobialagents,notthestatusofmicrobialsinrabbitmodel.Thereforethefirstpartofthistitleshouldberemoved.標(biāo)題“脾切除加斷流術(shù)門脈高壓癥兔腸微生態(tài)狀況及微生態(tài)制劑的干預(yù)研究”大模型的腸微生態(tài)狀況。因此這個(gè)標(biāo)題的前一部分可以刪除。“微生態(tài)制劑”Thisshouldbemorespecific,sinceitseemsthereisonlyoneagentinvolvedinthisstudy.“微生態(tài)制劑”Themanuscriptdidnotcomewithatitlepage,whichmustincludethetitle,runningtitle,andthedetailedauthorinformation.息未給國(guó)外編輯&ThissectionneedssignificantItshouldbetranslatedintoEnglish.EvenChinesejournalsrequirean.應(yīng)將其翻譯成英語。即使中文期也要求要有一個(gè)英要 istoolong.Mostjournalsrequire oflessthan250這個(gè)過長(zhǎng)。大多數(shù)期要求要少于250個(gè)字“①微生態(tài)制劑組（MOG：10只、②葡萄糖對(duì)照組(GOG：8只)分別灌服乳果糖+雙歧桿菌活菌、葡萄糖”Hereitisconfusing.Descriptionofeachgroupshouldberightafterthenameofthegroup.“①微生態(tài)制劑組（MOG：10只、②葡萄糖對(duì)照組(GOG：8只)分別灌服乳果糖+雙歧桿菌活菌、葡萄糖”這里有點(diǎn)。對(duì)每組的說明應(yīng)該放在該組名“5只僅作為模型對(duì)照Idon’tseeanydataonthisgroupArethese5rabbitsintheoriginal35,ornot?“5只僅作為模型對(duì)照”355只么，還是不包括 :Thereare5 whicharerelatedtothetopicofthepresentstudy.“微生態(tài)制劑”aspecificnameshouldbeprovided.：這里有5個(gè)，均與本研究的相關(guān)?！拔⑸鷳B(tài)制劑”應(yīng)提TheIntroductionispoorlywrittenandneedssignificantrevision.Itisveryshortandbrief.Thekeyconceptsandtechniquesinvolvedinthisstudyshouldallbeintroducedhere.Theauthorsfailedtodoso.這項(xiàng)涉及的主要概念及技術(shù)都應(yīng)該在這里加以介紹作者沒有這樣做Statementsmadeinthissectionshouldbesupportedbyproper在這一節(jié)的敘述應(yīng)適當(dāng)?shù)奈墨I(xiàn)加以支持Theauthorsshouldtryhardertostressoutwhythisstudyisimportantandclinicallysignificant.ThisisoneofthemostimportantelementsforagoodIntroduction.作者應(yīng)盡量強(qiáng)調(diào)這項(xiàng)研究之所以很重要的原因及其臨床意義。這是一個(gè)較好的引言的最重要的元一。MaterialsandThissectionneedssignificantrevisionbefore“ShamOperationGroupWhathavebeendoneinthisgroup?Therearetoomanydeathcasesinthisstudy.Idon’tthinkthisisnormalforthisoperation.Thisshouldbeexplained.在這項(xiàng)研究中的案例太多了。我認(rèn)為這不是這種手術(shù)的正常情況。對(duì)此“以二次法血吸蟲尾蚴建立門脈高壓癥動(dòng)物模型行血流動(dòng)力學(xué)檢查驗(yàn)證模型。”Moredetailsonthismodelandwhatprotocoltheauthorsfollowedshouldbeprovided,aswellastheprotocolonhowthemodelwastested.Ifthishasbeendonepreviouslyinthislabandpublishedalreadyareferenceshouldbelisted.“以二次法血吸蟲尾蚴建立門脈高壓癥動(dòng)物模型行血流動(dòng)力學(xué)檢查驗(yàn)證模型”關(guān)于這一模型的的細(xì)節(jié)信息及作者所遵循的方案以及如何測(cè)試模型的方案應(yīng)予以提供。如果這在本先前已經(jīng)完成且已經(jīng)，應(yīng)“5只兔僅作為模型對(duì)照。Wheredidthis5rabbitscomefrom?Theymustcomefromthesamesourceasthestudygroupsothattheycouldbeusedascontrol“5只兔僅作為模型對(duì)照?！?只兔出自哪里？它們必須與研究組的來Allreagents/medications/equipmentsshouldbeintroducedwithspecificdetails,whichincludethemodel,resource,dosage,andetc.Forexample,“送超微病理電鏡下觀察腸黏膜病變”,heretheinformationupontheEMshouldbeprovided.例如“送超微病理電鏡下觀察腸黏膜病變”,EM“總膽紅素（TBLL）Itshouldbe“TBIL”.AbbreviationssuchasTEandITSshouldbeTEITSIn1.3.5,圖像分析系統(tǒng)”needsmore在1.3.5節(jié)“圖像分析系統(tǒng)”需要有的說明The ysisisTheResultssectionistoosimpleandmoredescriptionshouldbe結(jié)果部分過于簡(jiǎn)單，應(yīng)提供的說明Theauthorsshouldbrieflyexplainwhytheywanttodoeachexperimentatthebeginningofeachparagraph,andwhatthesignificanceofeachgroupofdataattheend.Thiswillmaketheentiremanuscriptmorelikealogicstory.Theauthorsshouldgivemoredescriptionsintextonfiguresanddata,insteadofjustonesentenceineachparagraph.關(guān)于圖和數(shù)據(jù)作者應(yīng)給出的文字說明而不是每段中只有一句話描述Figuresshouldbenumberedas“Figure1”andetc,not“FigureA,B,C,Dshouldbemergedintoone,asarefigureE,F,G,A、B、C、DE、F、G、HThefigurelegendsarethere,butfailtomeettherequirementsofSCIfigurelegends.Thelegendsshouldbedescriptivewithoutanyfurtherysis.Nocomparisonshouldbeinthelegends.SCIIntable1,thereis“抽樣模型組”.Nopreviousdefinitionofthistermhasbeenprovided.Itneedsexplanation.1中，有“抽樣模型組”。前文并沒有提供這一詞語的定義。需要解釋一FiguresshouldputinappropriateformatsforSCI圖應(yīng)根據(jù)SCI期的要求，用合適的格式呈現(xiàn)“vsGOG、SOG、NOGisatthebottomoftable2.Thisisnotanappropriatewaytopresentstatisticaldata.Comparisonshouldbedonebetween2groupsateverytime,notwith3.“括號(hào)內(nèi)為陽性率”Itseemsitshouldbepercentage,butinthetable,no“%”isused.2底部的“vsGOG、SOG、NOG”。這里呈現(xiàn)統(tǒng)計(jì)數(shù)據(jù)的方式不太合適。23組?！袄ㄌ?hào)內(nèi)為陽性率”這似乎應(yīng)該是百分比，Throughoutthemanuscript,微生態(tài)制劑wasused.Butactuallythereisonlyoneagent“Bifidobacteriumused.Sothenameofthisagentshouldbeusedinsteadof貫穿全文使用了微生態(tài)制劑。但實(shí)際上，這里只有一種試劑“2.8腸道菌群DNA圖譜分析”.Theysisdescribedhereisnotveryconvincing.HowmanytimeshavethisDNAgelbeenrepeated?Aretheyallthesame?Inaddition,therearestrongvariationsobservedbetweenL3-10,thestudygroup.Howtoexplainthis,andhowcanyoudrawsuchconclusionfromthisinconsistentdata?Thefirst2paragraphsshouldbeinIntroduction,notThefindingsthatareeitherdifferentfromorconsistentwiththeotherstudiesshouldbediscussed.Theauthorsfailedtodothis.ThisisamajormistakeforwritingagoodDiscussion.Thereisnoparagraphindicatingthelimitationsofthestudy.Theauthorsshouldprovidealistofwhattheybelievethelimitationsare.沒有段落這項(xiàng)研究的局限性。作者應(yīng)列出他們所認(rèn)為的局限性有哪些ThereshouldbeoneparagraphattheendoftheDiscussiontoconcludewhattheauthorsfoundintheirstudyTheoneprovidedbytheauthorsisnotconciseenough.無Thereare