生物學(xué)數(shù)據(jù)庫及其檢索課件

biol生物信息學(xué)Bioinformatics生物學(xué)數(shù)據(jù)庫及其檢索第一節(jié)生物學(xué)數(shù)據(jù)庫簡介Chapter2、什么是數(shù)據(jù)庫?數(shù)據(jù)庫(database)是一類用于存儲和管理數(shù)據(jù)的計(jì)算機(jī)文檔,是統(tǒng)一管理的相關(guān)數(shù)據(jù)的集合,其儲存形式有利于數(shù)據(jù)信息的檢索與調(diào)用。二、生物學(xué)數(shù)據(jù)庫在生物信息學(xué)者們的努力下,人類基因組序列數(shù)據(jù)連同其它多種模式生物的序列數(shù)據(jù)及各自相應(yīng)的基因結(jié)構(gòu)與功能信息皆可供眾多生物學(xué)家們免費(fèi)接入與使用。模式生物BacillusDrosophilaRickettsiaHelicobacterurealyticummelanogasterprowazekiporBuchnerasp.EscherichiaAPhumanThermotogamaritimaThermoplasmamouseCaenorhabditisatBorreliaacidophilumelegansburgdorferiPlasmodiumBorreliafalciparumAquIrexmeningitidisMycobacteriaburgdorferiaeolicusmtuberculosis模式生物基因組計(jì)劃模式生物基因組計(jì)劃酵母線蟲、果蠅、細(xì)菌擬南芥等共約50多種已完成,70余種正在進(jìn)行。目前總量已達(dá)60億堿基對!Genomesizesinnucleotidepairs(base-pairsplasmidsvIrusesbacteplantsinsectsbonyfishamphibiansreptilesbirdsmammals10410501010101011部分生物基因組計(jì)劃網(wǎng)址生物種類0rganism網(wǎng)址(Address老鼠Mouseinformaticsjaxorg/mgd.html鼠http://ratmapgenguseDoghttp://mendel.berkeley.edu/dog.html狗牛豬羊雞locus.jouyinrafr/cgi-bin/bovmap/introPigri.bbsrc.ac.uk/pigmap/pigbase/pibase.htmlSheedirk.invermaycri.aChickenri.bbsrcac.uk/chickmap/chickbase/manager.html斑馬魚Zebrafiszfish,線蟲CaenorhabditishtLp://ddbi.nig.ac.ip/htmis/celeganselegansm1/CE-INDEX.htmlDictyoste/iuwhttp://glamdring.ucsd.edu/others/dsmith/dicdiscoideumtvdb.html果蠅Drosophila蚊子Mosquitoklab.agsci.colostate.edt擬南芥/rabidopsis棉花Cottonscaffold.biologiesuni-k1.de/beanreF玉米水稻Ricestaff.or.jp大豆:8000/main.h樹Trees生物學(xué)數(shù)