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病理學(xué)(南開大學(xué))知到智慧樹章節(jié)測試課后答案2024年秋南開大學(xué)緒論單元測試
Techniquesusedforcollectingbiopsysampleinclude:(
)
A:AlltheotheroptionsareincludedB:Scratching
C:EndoscopicforcepsD:LocalexcisionE:Deeporganpuncture
答案:Alltheotheroptionsareincluded
第一章單元測試
A17-year-oldboyinfectedwithhepatitisAexperiencesmildnauseaforabout1weekanddevelopsverymildscleralicterus.Onphysicalexamination,hehasminimalrightupperquadranttenderness.LaboratoryfindingsincludeaserumASTof68U/L,ALT75U/L,andtotalbilirubin5.lmg/dL.Theincreaseinthispatient'sserumenzymelevelsmostlikelyresultsfromwhichofthefollowingchangesinthehepatocytes?
A:DefectsinthecellmembraneB:DispersionofribosomesC:Swellingofthemitochondria
D:Clumpingofnuclearchromatin
E:Autophagybylysosomes
答案:DefectsinthecellmembraneAnexperimentanalyzescellsforenzymeactivityassociatedwithsustainedcellularproliferation.Whichofthefollowingcellsismostlikelytohavethehighesttelomeraseactivity?
A:ErythrocytesB:EndothelialcellsC:Neurons
D:GermcellsE:Neutrophils
答案:Neurons
Inaclinicaltrial,achemotherapeuticagentisgiventopatientswithbreastcancermetastases.Samplesofthecancercellsareobtainedandassessedforthepresenceofdeathoftumorcellsbyapoptosis.Mutationalinactivationofwhichofthefollowingproductsismostlikelytorendertumorcellsresistanttotheeffectsofsuchanagent?
A:CytochromeP-450B:p53C:NF-kappaBD:BCL-2E:GranzymeB
答案:NF-kappaBA22-year-oldwomanhasacongenitalanemiathathasrequiredmultipletransfusionsofRBCsformanyyears.Onphysicalexamination,shenowhasnosignificantfindings;however,liverfunctiontestsshowreducedserumalbumin.Whichofthefollowingfindingswouldmostlikelyappearinaliverbiopsyspecimen?
A:Steatosisinhepatocytes
B:GlycogeninhepatocytesC:Bilirubinincanaliculi
D:HemosiderininhepatocytesE:Amyloidinportaltriads
答案:HemosiderininhepatocytesA69-year-oldmanhashaddifficultywithurination,includinghesitancyandfrequency,forthepast5years.Adigitalrectalexaminationrevealsthattheprostateglandispalpablyenlargedtoabouttwicenormalsize.Atransurethralresectionoftheprostateisperformed,andthemicroscopicappearanceoftheprostate“chips”obtainedisthatofnodulesofglandswithinterveningstroma.Whichofthefollowingpathologicprocesseshasmostlikelyoccurredintheprostate?
A:HyperplasiaB:DysplasiaC:MetaplasiaD:ApoptosisE:FattychangeF:Hypertrophy
答案:HyperplasiaA33-year-oldwomanhashadincreasinglethargyanddecreasedurineoutputforthepastweek.Laboratorystudiesshowserumcreatininelevelof4.3mg/dLandureanitrogenlevelof40mg/dL.Arenalbiopsyisperformed,andthespecimenisexaminedusingelectronmicroscopy.Whichofthefollowingmorphologicchangesmostlikelysuggestsadiagnosisofacutetubularnecrosis?
A:PlasmamembraneblebsB:Nuclearfragmentation
C:RibosomaldisaggregationD:Chromatinclumping
E:Mitochondrialswelling
答案:Nuclearfragmentation
A63-year-oldmanhasa2-yearhistoryofworseningcongestiveheartfailure.Anechocardiogramshowsmitralstenosiswithleftatrialdilation.Athrombusispresentintheleftatrium.Onemonthlater,heexperiencesleftflankpainandnoteshematuria.LaboratorytestingshowselevatedserumAST.Whichofthefollowingpatternsoftissueinjuryismostlikelytobepresent?
A:Caseousnecrosis
B:Coagulativenecrosis
C:FatnecrosisD:GangrenousnecrosisE:Liquefactivenecrosis
答案:Coagulativenecrosis
Onaroutinevisittothephysician,anotherwisehealthy51-year-oldmanhasabloodpressureof150/95mmHg.Ifthepatient'shypertensionremainsuntreatedforyears,Whichofthefollowingcellularchangesisunlikelytooccurinmyocardium?
A:HemosiderosisB:HyperplasiaC:MetaplasiaD:AtrophyE:Hypertrophy
答案:Hemosiderosis;Hyperplasia;Metaplasia;Atrophy
Inanexperiment,cellsaresubjectedtoradiantenergyintheformofx-rays.Thisresultsincellinjurycausedbyhydrolysisofwater.Whichofthefollowingcellularenzymesdoesnotprotectcellsfromthisdamage?
A:LactatedehydrogenaseB:EndonucleaseC:ProteaseD:GlutathioneperoxidaseE:Phospholipase
答案:Lactatedehydrogenase;Endonuclease;Protease;PhospholipaseA68-year-oldwomansuddenlylostconsciousnessand,onawakening1hourlater,shecouldnotspeakormoveherrightarmandleg.Twomonthslater,aheadCTscanshowedalargecysticareaintheleftparietallobe.Whichofthefollowingpathologicprocesseshasmostlikelyoccurredinthebrain?
A:LiquefactivenecrosisB:ApoptosisC:CoagulativenecrosisD:KaryolysisE:Fatnecrosis
答案:Liquefactivenecrosis
第二章單元測試
A60-year-oldwomandevelopedchestpainthatpersistedfor4hours.Aradiographicimagingprocedureshowedanapparentmyocardialinfarctioninvolvinga3×4cmareaoftheposteriorleftventricularfreewall.Laboratoryfindingsshowedserumcreatinekinaseof600U/L.Thepatientreceivedbothanti-arrhythmicandpressoragentstotreatthedecreasedcardiacoutputwhileinthehospital.Whichofthefollowingpathologicfindingswouldmostlikelybeseenintheleftventriclelmonthlater?
A:FibrousscarB:CoagulativenecrosisC:CompleteresolutionD:Abscess
E:Nodularregeneration
答案:FibrousscarAnexperimentinfectsonegroupoftestanimalswithviralhepatitis.Twomonthslater,completerecoveryofthenormalliverarchitectureisobservedwhentheliversfromtheseanimalsareexaminedmicroscopically.Asecondtestgroupisinfectedwithbacterialorganisms,andafterthesameperiodoftime,fibrousscarsfromresolvingabscessesareseenmicroscopicallyinthelivers.Whichofthefollowingfactorsbestexplainsthedifferentoutcomesforthetwotestgroups?
A:LocationofthelesionB:Extentofdamagetothebileducts
C:
Extentoflivercellinjury
D:Natureoftheetiologicagent
E:Injurytotheconnectivetissueframework
答案:Injurytotheconnectivetissueframework
A23-year-oldwomanreceivingcorticosteroidtherapyforanautoimmunediseasehasanabscessonherupperouterrightarm.Sheundergoesminorsurgerytoinciseanddraintheabscess,butthewoundhealspoorlyoverthenextmonth.Whichofthefollowingaspectsofwoundhealingismostlikelytobedeficientinthispatient?
A:FibroblastgrowthfactorelaborationB:NeutrophilinfiltrationC:CollagendepositionD:Re-epithelization
E:Serineproteinaseproduction
答案:CollagendepositionAcesareansectionisperformedona20-year-oldwomantodeliveraterminfant,andthelowerabdominalincisionissutured.Thesuturesareremovedlweeklater.Whichofthefollowingstatementsbestdescribesthewoundsiteatthetimeofsutureremoval?
A:NomorewoundstrengthwillbegainedB:Collagendegradationexceedssynthesis
C:Granulationtissueisstillpresent
D:TypeIVcollagenpredominates
E:Woundstrengthis80%ofnormaltissue
答案:Granulationtissueisstillpresent
A40-year-oldmanunderwentlaparotomyforaperforatedsigmoidcolondiverticulum.Awoundinfectioncomplicatedthepostoperativecourse,andsurgicalwounddehiscenceoccurred.Primaryclosurewasnolongerpossible,andthewound"granulatedin."Sixweekslater,thewoundisonlyl0%ofitsoriginalsize.Whichofthefollowingprocessesbestaccountsfortheobserveddecreaseinwoundsizeoverthepast6weeks?
A:ElaborationofadhesiveglycoproteinsB:Increaseinsynthesisofcollagen
C:
Resolutionofsubcutaneousedema
D:Myofibroblastcontraction
E:Inhibitionofmetalloproteinases
答案:Myofibroblastcontraction
Inanexperimentinvolvingobservationsonwoundhealing,researchersnotedthatintracytoplasmiccytoskeletalelements,includingactin,interactwiththeextracellularmatrixtopromotecellattachmentandmigrationinwoundhealing.Whichofthefollowingsubstancesismostlikelyresponsibleforsuchinteractionbetweenthecytoskeletonandtheextracellularmatrix?
A:EpidermalgrowthfactorB:IntegrinC:Platelet-derivedgrowthfactor
D:Fibronectin
E:VascularendothelialgrowthfactorF:TypeIVcollagen
答案:IntegrinInanexperiment,releaseofepidermalgrowthfactorintoanareaofdenudedskincausesmitogenicstimulationoftheskinepithelialcells.Whichofthefollowingproteinsismostlikelytobeinvolvedintransducingthemitogenicsignalfromtheepidermalcellmembranetothenucleus?
A:
CyclicAMPB:Cyclin-dependentkinaseC:
Gproteins
D:RASproteinsE:CyclinD
答案:RASproteinsAnexperimentanalyzesfactorsinvolvedinthecellcycleduringgrowthfactor-inducedcellularregenerationinatissueculture.CyclinBsynthesisisinduced;thecyclinBthenbindsandactivatescyclin-dependentkinase1(CDK1).Theactivekinaseproducedbythisprocessismostlikelytocontrolprogressioninwhichofthefollowingphasesofthecellcycle?
A:G0toG1
B:G1toSC:G2toMD:StoG2
E:MtoG1
答案:G2toMAnexperimentisconductedinvolvingcellularaspectsofwoundhealing.Componentsoftheextracellularmatrixareanalyzedtodeterminetheirsitesofproductionandtheirbindingpatternstoothertissuecomponents.Whichofthefollowingmoleculessynthesizedbyfibroblastscanbestbindtocellularintegrinsandextracellularcollagenandattachepidermalbasalcellstobasementmembrane?
A:DermatansulfateB:Hyaluronicacid
C:FibronectinD:ProcollagenE:Heparin
答案:FibronectinInanexperiment,surgicalincisionsaremadeinastudygroupoflaboratoryrats.Observationsaboutthewoundsarerecordedovera2-weekperiodusingavarietyofchemicalmediators.Whichofthefollowingstepsintheinflammatory-repairresponseisimpossibleaffectedbyneutralizationoftransforminggrowthfactor-β?
A:ProductionofcollagenB:LeukocyteextravasationC:Increaseinvascularpermeability
D:ChemotaxisoflymphocytesE:Migrationofepithelialcells
答案:Leukocyteextravasation;Increaseinvascularpermeability
;Chemotaxisoflymphocytes;Migrationofepithelialcells
第三章單元測試
A52-year-oldwomanwithnomajormedicalproblemstakesalongairplaneflightacrossthePacificOcean.UponarrivalatSydney'sKingsfordSmithairportfollowingtheflightfromLosAngeles,shecannotputhershoesbackon.Thereisnopainortenderness.Whichofthefollowingisthemostlikelyexplanationforthisphenomenon?
A:Alotofdrinkswereservedinthefirstclasssection.
B:Venoushydrostaticpressurebecameincreased.
C:Acellulitisdevelopedinherlegs.D:ActivationofHagemanfactorhasledtobradykininproduction.
E:Femoralveinthrombosisdeveloped.
答案:Venoushydrostaticpressurebecameincreased.
A56-year-oldmanhashadincreasingdifficultybreathingforthepastweek.Onphysicalexaminationhehasnofever.Auscultationofhischestrevealsdiminishedbreathsoundsanddullnesstopercussionbilaterally.Thereis2+pittingedemapresenttothelevelofhisthighs.Achestradiographrevealsbilateralpleuraleffusions.Whichofthefollowinglaboratorytestfindingsishemostlikelytohave?
A:AnemiaB:HypoalbuminemiaC:NeutrophiliaD:HypernatremiaE:Glucosuria
答案:HypoalbuminemiaAstudyofatherogenesisisperformed.Thereisapropensityforatheromastoformatmusculararterialbranchpoints,suchasthecarotidandaorticbifurcations.Whichofthefollowingeventsinthearteriesattheselocationsismostlikelytoinitiateatherogenesis?
A:EndothelialdysfunctionB:Hypoxemia
C:Lacticacidosis
D:CollagensynthesisE:Cholesterolbreakdown
答案:EndothelialdysfunctionA61-year-oldmanhasthesuddenonsetofseverechestpain.VitalsignsincludeT37°C,P102/minute,RR20/minute,andBP80/40mmHg.Anelectrocardiogramdemonstrateschangesthatareconsistentwithmyocardialischemiainvolvingtheleftlateralventricularfreewall.Heisgiventhrombolytictherapywithtissueplasminogenactivator(tPA)3hoursaftertheonsetofchestpain.Howeverhisserumcreatininekinaseisfoundtobe450U/L(elevated)3hoursafterthistherapy.Whichofthefollowingcellulareventshasmostlikelyoccurred?
A:ReperfusioninjuryB:Drug-inducednecrosisC:Cellularregeneration
D:Myofiberatrophy
E:Increasedsynthesisofcreatinekinase
答案:ReperfusioninjuryAclinicalstudyisperformedwithsubjectswhohavethrombocytopenia<10,000/microliter.Thesepatientsareobservedtohavedefectsincoagulationwithspontaneousbleedingcharacterizedbymultiplepetechiaeandpurpuraandstoolsamplespositiveforoccultblood.Whichofthefollowingcoagulationfunctionsismostlikelytoremainlargelyintactinthesepatients?
A:Adherencetoinjuredvascularwalls
B:ConversionoffibrinogentofibrinC:Increaseinsurfacesitesforcoagulation
D:Inductionofvasoconstriction
E:Releaseofsubstancesthatneutralizeheparin
答案:ConversionoffibrinogentofibrinA70-year-oldmanseeksmedicalattentionbecauseofshortnessofbreathonminimalexertion.Aposteroanteriorchestradiographrevealsbluntingoftherightcostophrenicsulcusinterpretedasaright-sidedpleuraleffusion.Theaspiratedfluidisstrawcoloredandclear.Theproteinconcentrationislow,andthespecificgravityis1.011.Microscopicexaminationrevealsanoccasionalmesothelialcell.Whichofthefollowingisthemostlikelycauseoftheeffusion?
A:LeftventricularheartfailureB:TuberculosisC:MesotheliomaD:Pneumonia
E:Decreasedoncoticpressure
答案:LeftventricularheartfailureTwodaysfollowingacholecystectomy,a32-year-oldhospitalizedwomanhassuddenonsetofdyspnea,pleuralpain,andcoughproductiveoffrothy,blood-tingedsputum.Ventilation-perfusionscintigraphyindicatesaperfusiondefect.Ifitwerepossibletoexamineaportionoftheaffectedlung,whichofthefollowingwouldmostlikelyhavebeenfound?
A:Disseminatedintravascularcoagulation(DIC)
B:GeneralizedthrombosisC:Anemic(whiteorpale)infarctionD:Airembolism
E:Hemorrhagic(red)infarct
答案:Hemorrhagic(red)infarct
A36-year-oldmandiesduringcardiacsurgery.Hehadahistoryoflong-standingrheumaticheartdiseasewithmitralstenosis.Atautopsy,thepathologistreportsfindingsconsistentwithmitralstenosisandnotedthepresenceof‘heartfailurecells’.Thisfindingresultsfrom().
A:activationofthecoagulationcascadeB:hyperemiaofthelungs
C:myocardialhyperemia
D:chronicpassivecongestionofthelungs
E:hypoxicmyocardialinjury
答案:chronicpassivecongestionofthelungs
Duringalaboratoryexerciseoncoagulationtesting,a23-year-oldmedicalstudentisfoundtohaveaprolongedbleedingtime.Shehashadalonghistoryof‘easybleeding’withfrequentbleedingofthegums,epistaxis,cutaneousbleeding,andmenorrhagia.FurthertestingrevealedadeficiencyofvonWillebrandfactor.Whichofthefollowingthrombogenicprocessesinvolvingplateletsismostdirectlyimpaired?
A:FormationoffibrinogenbridgesB:ConformationalchangewithactivationofphospholipidsurfaceC:AdhesionD:Releasereaction
E:Stabilizationofplateletplug
答案:AdhesionFluidisaspiratedfromthegrosslydistendedabdomenofa47-year-oldchronicalcoholicman.Thefluidisstrawcoloredandclearandisfoundtohaveaproteincontent(largelyalbumin)of2.5g/dL.Whichofthefollowingisnotthemaincauseofthepatient'sfluidaccumulation?
A:DecreasedsodiumretentionB:BlockageoflymphaticsC:InflammatoryexudationD:IncreasedcapillarypermeabilityE:Decreasedoncoticpressure
答案:Decreasedsodiumretention;Blockageoflymphatics;Inflammatoryexudation;Increasedcapillarypermeability
第四章單元測試
A22-year-oldmandevelopsmarkedrightlowerquadrantabdominalpainoverthepastday.Onphysicalexaminationthereisreboundtendernessonpalpationovertherightlowerquadrant.Laparoscopicsurgeryisperformed,andtheappendixisswollen,erythematous,andpartlycoveredbyayellowishexudate.Itisremoved,andamicroscopicsectionshowsinfiltrationwithnumerousneutrophils.Thepainexperiencedbythispatientispredominantlytheresultofwhichofthefollowingtwochemicalmediators?
A:Prostaglandinandbradykinin
B:LeukotrieneandHPETEC:Interleukin-1andtumornecrosisfactorD:ComplementC3bandIgG
E:Histamineandserotonin
答案:Prostaglandinandbradykinin
A45-year-oldmanhasbeenworkinghardalldaylongcarryingloadsofbrickstobuildawall.Hetakesanon-steroidalanti-inflammatorydrug(ibuprofen).Whichofthefollowingprocessesisthisdrugmostlikelytodiminishinhisarms?
A:ScarformationB:ThrombosisC:FibrinolysisD:Pain
E:Necrosis
答案:Pain
Withinminutesfollowingabeesting,a37-year-oldmandevelopsmarkedrespiratorystridorwithdyspneaandwheezing.Healsodevelopsswellinganderythemaseeninhisarmsandlegs.Aninjectionofepinephrinehelpstoreversetheseeventsandherecoverswithinminutes.Whichofthefollowingchemicalmediatorsismostimportantinthepathogenesisofthisman'scondition?
A:ComplementC5aB:TumornecrosisfactorC:Histamine
D:Nitricoxide
E:Bradykinin
答案:Histamine
Inanexperiment,lymphaticchannelsareobservedinnormalsofttissuepreparations.Staphylococcusaureusorganismsareinnoculatedintothetissuesandtheimmunologicresponseisobservedoverthenext24hours.Whichofthefollowingfunctionsismostlikelytobeservedbytheselymphaticstoproduceaspecificimmuneresponsetotheseorganisms?
A:RemoveextravasculartissuefluidB:Transportantigenpresentingcells
C:Serveasaroutefordisseminationofinfection
D:Provideanemigrationpointforneutrophils
E:Carrylymphocytestoperipheraltissuesites
答案:Transportantigenpresentingcells
A65-year-oldwomanhashadafeverforthepastday.Onphysicalexaminationhertemperatureis39°Candbloodpressure90/50mmHgwithheartrateof106/minute.LaboratorystudiesshowaWBCcountof12,510/microliterandWBCdifferentialcountof78segs,8bands,11lymphs,and3monos.AbloodcultureispositiveforEscherichiacoli.Hercentralvenouspressurefallsmarkedly.Shegoesintohypovolemicshockasaresultofthewidespreadinappropriatereleaseofachemicalmediatorderivedfrommacrophages.Shedevelopsmultipleorganfailure.Whichofthefollowingmediatorsismostlikelytoproducethesefindings?
A:BradykininB:NitricoxideC:
ComplementC3aD:Prostacyclin
E:Histamine
答案:NitricoxideA56-year-oldmanhashadincreasingdyspneafor6years.Hehasnocoughorfever.Hehadchronicexposuretoinhalationofsilicadustformanyyearsinhisjob.Achestx-raynowshowsincreasedinterstitialmarkingsandparenchymal1to3cmsolidnodules.Hispulmonaryproblemsaremostlikelytobemediatedthroughwhichofthefollowinginflammatoryprocesses?
A:Foreignbodygiantcellformation
B:Neutrophilicinfiltratesproducingleukotrienes
C:MacrophageelaborationofcytokinesD:MastcellhistaminereleaseE:Plasmacellsynthesisofimmunoglobulins
答案:MacrophageelaborationofcytokinesA40-year-oldwomanhadlaparoscopicsurgery3monthsago.Nowshehasasmall0.5cmnodulebeneaththeskinattheincisionsitethatwassutured.Whichofthefollowingcelltypesismostlikelytobemostcharacteristicoftheinflammatoryresponseinthissituation?
A:NeutrophilB:Mastcell
C:Giantcell
D:Eosinophil
E:Plasmacell
答案:Giantcell
A43-year-oldwomanhashadachroniccoughwithfeverandweightlossforthepastmonth.Achestradiographrevealsmultiplenodulesfrom1to4cminsize,someofwhichdemonstratecavitationintheupperlobes.Asputumsamplerevealsthepresenceofacidfastbacilli.Whichofthefollowingcellsisthemostimportantinthedevelopmentofherlunglesions?
A:NeutrophilB:PlateletC:FibroblastD:Macrophage
E:Mastcell
答案:Macrophage
Aroutinecompletebloodcountperformedona22-year-oldmedicalstudentrevealsanabnormalityinthedifferentialleukocytecount.Shehasbeencomplainingoffrequentsneezingand‘watery’eyesduringthepastseveralweeksandreportsthatshefrequentlyhadsuchepisodesinthespringandsummer.
答案:0
第五章單元測試
Whichoneofthefollowingitemsismosthelpfulindistinguishingpoorlydifferentiatedcarcinomafromsarcoma?
A:TheageofpatientB:Thegrowthpattern
C:Thelocationofthetumor
D:ThemannerofspreadE:Reticulumfiberstain
答案:Reticulumfiberstain
ThepatientsurvivalratewithstageT4N1M1neoplam5yearsfromthetimeofdiagnosisislessthan50%,regardlessoftherapy.Whichofthefollowingclinicalfindingsismostlikelytobecharacteristicofthisgroupofpatients?
A:IcterusB:SplenomegalyC:CardiacmurmurD:Cachexia
E:Tympany
答案:Cachexia
Ahealthy22-year-oldwomanundergoesaroutinephysicalexamination.Adiscrete,firm,rubbery,movablemassisfoundintheleftbreast.Shehasnoaxillarylymphadenopathy.Theskinoverlyingthebreastandthenippleappearnormal.Whichofthefollowingneoplasmsismostlikelytobepresentinthiswoman?
A:Fibroadenoma
B:MalignantlymphomaC:LeiomyomaD:LipomaE:Intraductalcarcinoma
答案:Fibroadenoma
62-year-oldmanhascomplainedofpainonurinationforthepastweek.Heisafebrile.Oncystoscopy,aslightlyerythematous1cmdiameterareaisseenonthebladdermucosa.Thisareaisbiopsiedandonmicroscopicexaminationshowscellswithmarkedhyperchromatismandincreasednuclear/cytoplasmicratioinvolvingthefullthicknessoftheepithelium.However,thesechangesareconfinedtotheepitheliumabovethebasementmembrane.Whichofthefollowingtermsbestdescribesthesebiopsyfindings?
A:
CarcinomainsituB:MinimaldysplasiaC:MicroinvasionD:HyperplasiaE:Metaplasia
答案:
CarcinomainsituA60-year-oldmanwhohasa90packyearhistoryofcigarettesmokinghashadachroniccoughforthepast10years.Hehasbeguntoloseweight(3kg)duringthepastyear.Noabnormalfindingsarenotedonphysicalexamination.Hehasachestradiographthatrevealsarighthilarmass.Asputumcytologyshowsatypical,hyperchromaticsquamouscells.Whatisthemostcommoninitialpathwayformetastasesfromthislesion?
A:BronchiB:ContiguousspreadtochestwallC:PleuralcavityD:Bloodstream
E:Lymphatics
答案:LymphaticsAllneoplasmsarecollectivelyreferredtoascancers.
A:對(duì)B:錯(cuò)
答案:錯(cuò)Papillomaisabenignneoplasmthatmostoftenarisesfromsurfaceepithelium.
A:錯(cuò)B:對(duì)
答案:對(duì)Poorlydifferentiatedsquamouscellcarcinomasformintercellularbridgesandpinkkeratinizedcytoplasm.
A:對(duì)B:錯(cuò)
答案:錯(cuò)Paraneoplasticsyndromescanbeexplainedbytheanatomicdistributionofthetumor.
A:對(duì)B:錯(cuò)
答案:錯(cuò)Biopsyofsentinellymphnodesisoftenusedtoassessthepresenceorabsenceofmetastaticlesionsinthelymphnodes.
A:對(duì)B:錯(cuò)
答案:對(duì)
第六章單元測試
50-year?old?man?has?blood?pressure?of?150/90?mm?Hg(normalblood?pressure?is?120/90?mm?Hg).?If?this?person?remains?untreated?for?years,which?of?the?following?alterations?will?be?seen?in?the?myocardium?
A:HypertrophyB:NecrosisC:MetaplasiaD:AtrophyE:Dysplasia
答案:HypertrophyA65-year-oldmanwasfoundtohavea5-cmpulsatilemassinhisabdomenduringaroutinephysicalexamination.Angiographyrevealsamarkeddilationinhisaortadistaltotherenalarteries.Whichofthefollowingisthemostlikelycauseofthisaneurysm?
A:Acongenitaldefect
B:RheumaticfeverC:
Trauma
D:AtherosclerosisE:Hypertension
答案:Atherosclerosis40.A65-year-oldmandevelopsintensecrushingsubsternal,chestpainthatisnotrelievedbynitroglycerin.TheECGshowsST-segmentelevationandabnormalQwaves.Hisconditionrapidlyworsensandhedies2dayslater.Atautopsya2.5cm2necroticareaisfoundthatinvolvestheanteriorleftventricle.Whatisthemostlikelycauseofthispatient'smyocardialinfarction?
A:VasospasmoftherightcoronaryarteryB:CompleteocclusionoftheleftcircumflexcoronaryarteryC:FibrinoidnecrosisofmaintrunkofleftcoronaryarteryD:SeverestenosisofallthreemainbranchesofcoronaryarterywithoutthrombosisE:Thrombosisoftheanteriordescendingbranchoftheleftcoronaryartery
答案:ThrombosisoftheanteriordescendingbranchoftheleftcoronaryarteryA57-year-oldmanhashadbloodpressuremeasurementsintherangeof160/95to180/110mmHgformanyyears.Hehastakennomedications.Arenalscanrevealskidneysofnormalsizeforage.Thesefindingswithbenignnephrosclerosisaremostlikelytooccurwithwhichofthefollowingvascularchanges?
A:HyperplasticarteriolosclerosisB:ArterialmuralthrombosisC:Hyalinearteriolosclerosis
D:Monckeberg'smedialcalcificsclerosisE:Complexcalcifiedatherosclerosis
答案:Hyalinearteriolosclerosis
A51-year-oldmanhasthesuddenonsetofsubsternalchestpainwhichradiatestohisleftarmandneck.Hebecomeslight-headedanddiaphoreticoverthenext8hours.Hegoestotheemergencyroom.Onexaminationheisafebrilebuthasaheartrateof96/minutewithanirregularrhythm.LaboratorystudiesshowanincreasedserumtroponinI.Whichofthefollowingfeatureswouldbemostprominentbyhistopathologicexaminationofhismyocardiumatthispointintime?
A:CoagulativeNecrosisB:
CapillaryproliferationC:MacrophageinfiltrationD:
NeutrophilicinfiltrationE:Collagendeposition
答案:CoagulativeNecrosisPeripheralarterydiseasedevelopsifplaquedepositsblockbloodflowtothearteriesthatsupplythearms,pelvis,orlegs.
A:錯(cuò)B:對(duì)
答案:對(duì)Grossfeatureofhypertensiveheartdiseaseisleftventricalhypertrophy.
A:錯(cuò)B:對(duì)
答案:對(duì)Familyhistory,age,geneticabnormalities,anddiet,theseareallcalledconstitutionalriskfactor.
A:對(duì)B:錯(cuò)
答案:錯(cuò)Myocardialruptureismostcommon10-14daysafterinfarction.
A:錯(cuò)B:對(duì)
答案:錯(cuò)Fattystreaksarecomposedofsmoothmusclecells.
A:錯(cuò)B:對(duì)
答案:錯(cuò)
第七章單元測試
Anasymptomatic10-year-oldchildwithachestradiographshowingasubpleuralnoduleintherightmid-lungfieldandenlargedmediastinallymphnodesprobablyhas:
A:SecondarytuberculosisB:PrimarytuberculosisC:MiliarytuberculosisD:CoccidiodomycosisE:Aspergillosis
答案:PrimarytuberculosisIfapersonquitssmoking,he/shecanexpecttobenefitfromallofthefollowingEXCEPT:
A:ReversalofemphysematouschangesB:Lowerriskforlunginfections
C:Decreasedriskforlungcancerinclosefamilymembers
D:AbatementofchronicbronchitisE:Diminshedriskforlungcancer
答案:ReversalofemphysematouschangesWhichofthefollowingfindingsisLEASTlikelytobediagnosedbybronchoalveolarlavage(BAL)ina45-year-oldmalewithfeverandcough:
A:PneumocystiscariniiB:AdenocarcinomaC:MycobacteriumtuberculosisD:Cytomegalovirus
E:Pulmonaryhamartoma
答案:Pulmonaryhamartoma
WhichofthefollowingpatientsisLEASTlikelytohavedevelopedanobstructivelungdisease:
A:A60-year-oldfemalec
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