Glu-AMS-TEA-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEGlu-AMSTEACat.No.:HY-159628ACASNo.:1810728-44-9分?式:C??H??N?O?S分?量:576.62作?靶點(diǎn):Aminoacyl-tRNASynthetase;Bacterial作?通路:MetabolicEnzyme/Protease;Anti-infection儲(chǔ)存?式:-20°C,storedundernitrogen*Insolvent:-80°C,6months;-20°C,1month(storedunder

nitrogen)溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:100mg/mL(173.42mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM1.7342mL8.6712mL17.3424mL5mM0.3468mL1.7342mL3.4685mL10mM0.1734mL0.8671mL1.7342mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month(storedundernitrogen)。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性Glu-AMSTEA?腸桿?氨酰-tRNA合成酶（GluRS）的競爭性抑制劑，其Ki為2.8nM。REFERENCES[1].SébastienPBlais,etal.tRNAGluIncreasestheAffinityofGlutamyl-tRNASynthetaseforItsInhibitorGlutamyl-Sulfamoyl-Adenosine,anAnalogueoftheAminoacylationReactionIntermediateGlutamyl-AMP:MechanisticandEvolutionaryImplications.PLoSOne.2015Jun1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemE3;10(6):e0130238.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax/p>