5-Aminolevulinic-acid-hydrochloride-ALA-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE5-Aminolevulinic acid hydrochlorideCat. No.: HY-N0305CAS No.: 5451-09-2Synonyms: ALA; 5-ALA分式: CHClNO分量: 167.59作靶點(diǎn): Autophagy; Mitophagy作通路: Autophagy儲存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (prote

2、ct fromlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 150 mg/mL (895.04 mM)H2O : 50 mg/mL (298.35 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 5.9669 mL 29.8347 mL 59.6694 mL5 mM 1.1934 mL 5.9669 mL 11.9339 mL10 mM 0.5967 mL 2.9835 mL 5.9669 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請

3、注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 5-Aminolevulinic acid hydrochloride (ALA)體內(nèi)紅素物合成的中間體，為四吡咯的前體。體外研究5-Aminolevulinic acid hydrochloride (ALA) is a non-fluorescent prodrug that leads to intracellularaccumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for

4、intraoperative identification and resection of these tumours. Median follow-up was 35.4 months (95% CI 1.0-1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE56.7). Contrast-enhancing tumour was resected completely in 90 (65%) of 139 patients assigned 5-aminolevulinic acid compared with 47 (36%) of 13

5、1 assigned white light (difference between groups 29%95% CI 17-40, p 2.戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Adv Sci (Weinh). 2019 Jan 20;6(5):1802057.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant gl

6、ioma: a randomised controlledmulticentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.2. Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012.7(9): p. e44885.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-