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1、Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Associationby Eric E. Smith, Gustavo Saposnik, Geert Jan Biessels, Fergus N. Doubal, Myriam Fornage, Philip B. Gorelick, Steve

2、n M. Greenberg, Randall T. Higashida, Scott E. Kasner, and Sudha SeshadriStrokeVolume 48(2):e44-e71January 23, 2021Copyright American Heart Association, Inc. All rights reserved.Left, Silent brain infarct (arrow) on magnetic resonance imaging (MRI) fluid-attenuated inversion recovery (FLAIR) scan. E

3、ric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart Association, Inc. All rights reserved.A small (4-mm) subcortical silent brain infarct is visible as a hypodensity in the left thalamus on computed tomography (A). Eric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart

4、Association, Inc. All rights reserved.There is a 5-mm left thalamic hyperintensity (arrow) on the fluid-attenuated inversion recovery (FLAIR) sequence (left) with clear evidence of cavitation based on cerebrospinal fluidlike hyperintensity on T2-weighted (middle) and hypointensity on T1-weighted (ri

5、ght) images. Eric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart Association, Inc. All rights reserved.Cortical silent brain infarct. Eric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart Association, Inc. All rights reserved.White matter lesions of presumed vascular

6、origin. Eric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart Association, Inc. All rights reserved.Fazekas visual rating scale for magnetic resonance imaging white matter hyperintensities (WMHs). Eric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart Association, Inc. A

7、ll rights reserved.Distribution of magnetic resonance imaging (MRI) white matter hyperintensity by age category in the general population, measured with the Fazekas scale (Figure 6). Eric E. Smith et al. Stroke. 2021;48:e44-e71Copyright American Heart Association, Inc. All rights reserved.Hazard ratio for future symptomatic stroke in individuals with a high burden of white matter hyperintensities

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