Bromodomain-inhibitor-8 - BET Bromodomain 抑制劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBromodomain inhibitor-8Cat. No.: HY-128703CAS No.: 1300031-70-2分式: CHClNO分量: 448.94作靶點(diǎn): Epigenetic Reader Domain作通路: Epigenetics儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 100 mg/mL (22

2、2.75 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.2275 mL 11.1373 mL 22.2747 mL5 mM 0.4455 mL 2.2275 mL 4.4549 mL10 mM 0.2227 mL 1.1137 mL 2.2275 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請根據(jù)您的實(shí)驗(yàn)動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使

3、；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 5 mg/mL (11.14 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 5 mg/mL (11.14 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE物

4、活性 Bromodomain inhibitor-8 (Intermediate 21)BET 溴端結(jié)構(gòu)域 的抑制劑，可于治療免疫性和炎癥類疾病。IC50 & Target BrdREFERENCES1. CHUNG, Chun-Wa, et al. BROMODOMAIN INHIBITORS FOR TREATING AUTOIMMUNE AND INFLAMMATORY Dl SEASES. WO2011/054843 Al.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021-