BM212 - Bacterial 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBM212Cat. No.: HY-100725CAS No.: 146204-42-4分式: CHClN分量: 414.37作靶點(diǎn): Bacterial作通路: Anti-infection儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) Ethanol : 5.56 mg/mL (13.42 mM; Need ultrasonic)DMSO

2、 : 40% PEG300 5% Tween-80 45% salineSolubility: 0.56 mg/mL (1.35 mM); Clear solution2. 請依序添加每種溶劑： 10% EtOH 90% (20% SBE-CD in saline)Solubility: 0.56 mg/mL (1.35 mM); Clear solution3. 請依序添加每種溶劑： 10% EtOH 90% corn oil1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 0.56 mg/mL (1.35 mM); C

3、lear solutionBIOLOGICAL ACTIVITY物活性 發(fā)揮殺菌活性與細(xì)胞內(nèi)細(xì)菌駐留,完全抑制胞內(nèi)分枝桿菌。REFERENCES1. Poce G et al. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One.2013;8(2)2. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multid

4、rug-resistant and intramacrophagic Mycobacteriumtuberculosis strains. Antimicrob Agents Chemother. 1998 Nov;42(11):3035-7.3. Deidda D et al. Bactericidal activities of the pyrrole derivative BM212 against multidrug-resistant and intramacrophagic Mycobacteriumtuberculosis strains.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 0