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分子生物學(xué)(MolecularBiology)知到章節(jié)測試答案智慧樹2023年最新山東第一醫(yī)科大學(xué)第一章測試
TheNucleicacidwillgetmaximumUVabsorbanceatwavelength_____()
參考答案:
260nm
ThecommoncomponentcomposedofDNAandRNAis_____()
參考答案:
Guanine
ThesecondarystructureofDNAis_____()
參考答案:
doublehelix
ThecorrespondinganticodontocodonACGis___()
參考答案:
CGU
SinglestrandDNA5’-CGGTA-3’canannealwiththefollowRNA_____()
參考答案:
5’-UACCG-3’
mRNAisusedas_____intranslation.()
參考答案:
template
AmountofTinRNAis0.25mol,soamountofAis_____.()
參考答案:
0.25mol
tRNAineukaryoticcellcontains_____()
參考答案:
5.8sRNA;5sRNA;18sRNA;28sRNA
ThebaseinDNA_____()
參考答案:
C;T;A;G
Stem-loopisatypeofsecondarystructurenotusuallyfoundintRNA.()
參考答案:
對
AllgenomesarecomposedofRNA.()
參考答案:
錯(cuò)
第二章測試
SequencesthatareremovedfromtheprimaryRNAtranscriptineukaryotesarecalled________.()
參考答案:
introns
Whichcharacterisnottrueforeukaryoticgenes?()
參考答案:
Alltheprotein-codinggenesinhighereukaryoteshaveintrons.
Whichisnotafeatureofenhancer?()
參考答案:
Ageneoftenhasonlyoneenhancer.
Theregulatorsofeukaryoticgeneexpressionconsistof________.()
參考答案:
enhancer;insulator;silencer
Allhousekeepinggeneshaveweakpromotorsandareregulatedtomaintaintheirgene
productsatconstantlowlevelconcentrations.()
參考答案:
錯(cuò)
第三章測試
BasedonMeselson-Stahlexperiment,eachdaughterDNAmoleculeiscomposedof()
參考答案:
oneoldandonenewstrand
Whichmechanismcanexplaintwostrandsaresynthesizedintheoppositedirection,inthereplicationfork?()
參考答案:
semidiscontinuousreplication
Althoughmammaliangenomeishuge,cellscanreplicatethegenomeinjustafewminutes.Whichisthemostpossiblereason?()
參考答案:
Hundredsofreplicationforksworksimultaneously
WhichisTUREabouttheinitiationofprokaryoticDNAreplication?()
參考答案:
DNAhelicaseunwindsDNAduplexatoriC
Whichis
FALSEabouttheterminationofprokaryoticDNAreplication?()
參考答案:
Coordinatethesynthesisoflaggingandleadingstrands
WhichisFALSEaboutDNApolIIIinprokaryotes?()
參考答案:
α,δ,ξsubunitsformcoreenzyme
MitochondrialDNAreplicatesin()
參考答案:
D-loopreplication
RNAprimerinDNAreplication()
參考答案:
isrequiredbyallOkazakifragments;provides3’-OHtosynthesizeDNA
DNAreplicationneeds()
參考答案:
helicase;primase;topoisomerase;DNAligase
WhatarethedifferencesofeukaryoticDNAreplicationfromprokaryotes?()
參考答案:
thereplicationoriginofeukaryotesisshorterthanthatinprokaryotes;telomereandtelomeraseaidterminationofeukaryotes;eukaryoticDNAisreplicatedinSphaseofcellcycle;eukaryoticDNAcontainsmultipleorigins
TheOkazakifragmentofeukaryotesislongerthanthatofprokaryotes.()
參考答案:
錯(cuò)
ReversetranscriptaseexertsthefunctionsofRNAdependentDNApolymeraseandDNAdependentDNApolymerase.()
參考答案:
對
第四章測試
WhichofthefollowingDNAdamagesbelongstoexogenousDNAdamage().
參考答案:
Ionizingradiation
WhichtypeofDNApointmutationswillnotleadtothechangeinaminoacid().
參考答案:
Silentmutation
whichbasesubstitutionbelowbelongsto“Transition”pointmutation.()
參考答案:
C→T
WhichiswrongbelowasdescribedfordirectlyundoingDNAdamagesrepair.()
參考答案:
null
InwhichprocessGG-NERandTC-NERshowdifferent()
參考答案:
DNAlesionrecognition
ThedeficiencyofNERrepairproteinsissusceptibleto_disease.()
參考答案:
Xerodermapigmentosum
Duringmismatchrepairinprokaryotes,thenewlysynthesizedDNAisrecognizedbythelackof()modification()
參考答案:
Methylation
DuringdoublestrandedDNAbreakrepair,NHEJshowsmoreprecisecomparedtoHR.()
參考答案:
錯(cuò)
DNAdamageisthemaincausefortheincreasedfrequencyofgenemutation.()
參考答案:
對
BaseexcisionrepairisoneofDNArepairpathwaystocorrectslargebaselesions.()
參考答案:
錯(cuò)
第五章測試
WhichcomponentoftheprokaryoteRNApolymeraseholoenzymeisinvolvedinrecognizingpromotersspecifictocertaintypesofgenes?()
參考答案:
σ
WhichRNApolymerasetranscribesthegeneofinsulin?()
參考答案:
RNApolymeraseII
AlltheRNAsbelowaretranscribedbyRNApolIexcept()
參考答案:
23SrRNA
Whichofthefollowingstepsoccursfirstinprokayotictranscription?()
參考答案:
formationofaclosedpromotercomplex
TheRhoproteinisinvolvedinthe_____stageoftranscription.()
參考答案:
termination
Inprokaryotes,RNApolymerasecanbindupstreamsequencesofpromotersdirectly.Eukaryotesneedsomeproteinstofacilitatethebinding.Whatarethenamesoftheseproteins?()
參考答案:
Transcriptionfactors
WhichtranscriptionfactorcanrecognizeandbindtoTATAbox?()
參考答案:
TFIID
AmutationtothissequenceineukaryoticmRNAwillaffecttheprocessbywhichthe3'-endpoly-AtailisaddedtothemRNA.()
參考答案:
AAUAAA
Thefunctionsof5’CapofeukaryoticmRNAinclude()
參考答案:
transportofthemRNAfromnucleustocytosol;;enhancementofthemRNA’stranslatability;;protectionofthemRNAfromdegradation;
Cis-actingelementsandtrans-actingfactorscontroltranscription.Thecis-actingelementsincludetheTATAbox,enhancersandotherelementsetal.()
參考答案:
對
RNAPolIIistheenzymesynthesizinghnRNAineukaryotes.Itisnotsusceptibletoamanitin.()
參考答案:
錯(cuò)
Eukaryotictranscriptionsisaccompaniedbytranslation.()
參考答案:
錯(cuò)
第六章測試
Weusuallycallcodonscontains5characteristics,amongwhichthedegeneracyofthegeneticcodemeans?()
參考答案:
Mostaminoacidshavemorethanonesetofcodons
AgenehasthebasesequenceACCCGTGCACGT.IftheAatthebeginningofthesequenceisdeleted,whatwillbehappen?()
參考答案:
AllofthecodonsafterApointwillbechanged
WhichbondisanaminoacidlinkedtothetRNA?()
參考答案:
ester
Theenergyrequiredforthestepofpeptidechainelongationinprokaryoticis?()
參考答案:
onlyGTP
TheShine-Dalgarnosequenceisfoundonthe________.()
參考答案:
mRNA
Amongthefollowingfactors,whichonecoulddelivertheaminoacyl-tRNAtotheAsiteofribosome?()
參考答案:
EF-Tu
ThespecificsequenceontheNterminusofsecretoryproteiniscalled()
參考答案:
signalpeptide
Whichproteinfactorhasthetranslocaseenzymeactivityineukaryotes:()
參考答案:
eEF-2proteinfactor
WhichoftheclassesofRNAmoleculesis/arepartoftheprocessof
translation?()
參考答案:
TransferRNA;MessengerRNA;RibosomalRNA
MessengerRNA(mRNA)ismadebyaprocesscalledtranslation.()
參考答案:
錯(cuò)
Polypeptidesunfoldinthecytoplasmofacelltoformafunctionalprotein.()
參考答案:
錯(cuò)
Thegeneticcodehasfourletters,A,T,G,andC.()
參考答案:
錯(cuò)
第七章測試
WhichisNOTafinalproductofgeneexpression?()
參考答案:
mRNA
Ifageneisexpressedatrelativelyconstantrateinalmostallthecells,itiscalleda(an)()
參考答案:
housekeepinggene
Themostefficientstepofgeneexpressionregulationis()
參考答案:
transcriptioninitiation
WhichoneisNOTacis-actingelement?()
參考答案:
activatorprotein
Theprokaryoticoperatorsequenceisusually().
參考答案:
locatedontheupstreamregionofpromoter
Intheregulationoflacoperon,whenthemediumcontainsbothglucoseandlactose,whichstatementistrue?()
參考答案:
bothrepressorandCAPareinactive
Inlacoperon,repressorproteincouldbindto()sequence.()
參考答案:
operator
Intheregulationoflacoperon,whenthemediumcontainsonlyglucose,whichstatementistrue?()
參考答案:
concentrationofcAMPislow,CAPisinactive
Ifageneisexpressedonlyincertainorgansortissues,thisiscalled()
參考答案:
spatialspecificityofgeneexpression
WhichisNOTthebasalcis-actingelementsineukaryotes?()
參考答案:
operator
Enhancersmustlocateontheupstreamregionofpromoter.()
參考答案:
錯(cuò)
Theactivechromatinusuallyshowslowlevelofmethylation.()
參考答案:
對
第八章測試
Whichstatementistrueaboutoncogenes?()
參考答案:
Theyareusuallyactivatedincancerdevelopment
Whichoneofthefollowingisoncogene?()
參考答案:
myc
Thefollowingchangespromoteoncogeneactivation,except()
參考答案:
Lossofheterozygosity
Themechanismsoftumorsuppressorgeneinactivationinclude()
參考答案:
Mutation;hypermethylation;Lossofheterozygosity
Inmostchronicmyelogenousleukemia,tumorigenesisiscausedbyoncogeneamplification()
參考答案:
錯(cuò)
第九章測試
ThebasicstepsofPCRreactionare:()
參考答案:
denaturation,annealing,extension
ThebasiccomponentsofthePCRsystemdoesnotinclude:()
參考答案:
NTP
WhichtechnologycanbeusedtoidentifyDNA?()
參考答案:
Southernblotting
Whicharerightaboutmolecularhybridization?()
參考答案:
FromtheunderstandingofDNAdenaturationandrenaturationphenomenon;Thehybridmoleculesmustbesingle
InthePCRreaction,thepurposeofannealingistomakethecombinationofprimerandtemplate.()
參考答案:
對
Proteinchiptechnologyhasthecharacteristicsoffastandhighthroughput,itcanbeusedtoanalyzethousandsofproteinsinthewholegenomelevelatthesametime.()
參考答案:
對
第十章測試
WhichofthefollowingstatementsisnottrueconcerningTypeIIrestrictionendonucleases?()
參考答案:
TheycancleavesingleDNA
Whichisnotnecessaryaspartofprokaryoticexpressionvector?()
參考答案:
PolyAsignal
Basedonthenamingrules,thefirstletterofarestrictionendonucleasemeans()
參考答案:
Bacterialgenus
Isocaudarnerpresents()
參考答案:
Variousrestrictionendonucleasesrecognizedifferentpalindromes,butproducesamestickyends
Plasmidsareusuallyintroducedintobacterialcellsby.()
參考答案:
Transformation
T4DNAligaserequires()
參考答案:
ATP
Ininsertionalinactivationscreening,thebacteriathataresensitivetotetracyclineandresistant
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