【醫(yī)學(xué)生物】組織胚胎學(xué)課件4

組織胚胎學(xué)課件

中國(guó)醫(yī)科大學(xué)基礎(chǔ)醫(yī)學(xué)院組胚—英文教學(xué)組1業(yè)精于勤荒于嬉行成于思?xì)в陔S→【醫(yī)學(xué)生物PPT，歡迎收藏分享】豆丁網(wǎng)友組織胚胎學(xué)課件

中國(guó)醫(yī)科大學(xué)1業(yè)精于勤荒于嬉行成于思?xì)UMANEMBRYOLOGYDepartmentofHistologyandEmbryologyChinaMedicalUniversityHUMANChapter4

FurtherDevelopmentofEmbryo

Chapter4FormationanddifferentiationoftrilaminargermdiscFormationanddifferentiation1.formationofepiblastandhypoblast

:

Bythe8thday,theinnercellmassdifferentiatesintotwolayersofcells

epiblast(columnar)hypoblast(cuboidal)bilaminargermdisc1.formationofepiblastandAmnioniccavityepiblasthypoblastBilaminargermdiscAmnionicepiblasthypoblastBila---epiblast:primaryectodermamnioticcavity:amnioticfluidroof:amniogeniccellsfloor:epiblast---epiblast:primaryectoderm---hypoblast:primaryendodermhypoblast→Heuser’smembrane→primaryyolksac---hypoblast:primaryendoderAmnioniccavityepiblasthypoblastBilaminargermdiscExtra-embryonicmesodermPrimaryyolksacAmnioniccavityepiblasthypoblBodystalkExtra-embryoniccavityExtra-embryonicmesodermPrimaryyolksacsecondaryyolksacBodystalkExtra-embryonicExtra

extra-embryonicmesoderm→extra-embryoniccavity(chorioniccavity)--viscerallayer--parietallayer/secondaryyolksac:yolksac---bodystalk(connectingstalk):formedbyextra-embryonicmesodermextra-embryonicmesoderm→2.formationofmesoderm:intheearlyofthe3rdweek---primitivestreak:cellsofepiblastproliferatetoformalongitudinalarrangedcellcord*determinationofheadandtailofgermdisc2.formationofmesoderm:2.formationofmesoderm:intheearlyofthe3rdweek---primitivestreak---primitivenode(primitiveknot)2.formationofmesoderm:int2.formationofmesoderm:intheearlyofthe3rdweek---primitivestreak:---primitivenode(primitiveknot)---primitivepit(blastopore)2.formationofmesoderm:int【醫(yī)學(xué)生物】組織胚胎學(xué)課件4---mesoderm:intra-embryonicmesoderm---endoderm:hypoblastcellsarereplacedbyepiblastcells---ectoderm:epiblastchangedthenameintoectoderm---mesoderm:intra-embryonicm

bytheendofthe3rdweek

trilaminargermdisc:endoderm+mesoderm+ectoderm

bytheendofthe3rdweek---headprocess→notochordaltube→notochord---buccopharyngealmembrane---cloacalmembranenotochord---headprocess→notochordaltu3.differentiationoftrilaminargermdisc4th–8thweeks---differentiation:samecellswhichareprimordialandinmuturedifferentiateintodifferentcellswhichhavespecificstructureandfunction---induction:sometissueseffectthedifferentiation,anddeterminethedifferentiatingorientationofanothertissue3.differentiationoftrilamina(1)

differentiationofectoderm:from18th–19thdays---neuralplate:neuro-epithelium(neuralectoderm):pseudostratifiedcolumnarepi.neuralplateNotochord(1)

differentiationofectoder(1)

differentiationofectoderm:from18th–19thdays---neuralplate---neuralgroove---neuralfoldNeuralgrooveNotochord(1)

differentiationofectoderNeuraltubeAnteriorandposteriorneuropores---neuraltube:→CNS/anteriorneuropore:closedby25thdays/posteriorneuropore:closedby27thdaysNeuraltubeAnteriorandposteranencephalySpinabifidaanencephalySpinabifida---neuraltube:CNS---neuralcrest:twolinesofcellcords→ganglions---neuraltube:CNS(2)differentiationofmesoderm:17thdayNeuralgrooveIntermediatemesodermLateralmesoderm

paraxialMesodermendoderm(2)differentiationofmesoderm---paraxialmesodermsomite:20thdays,3pairs/perday,42-44pairsbytheendof5thweeks-sclerotome:→bone,cartilage-dermatome:→dermisandhypodermis-myotome:→skeletalmuscle---paraxialmesodermIntermediatemesodermNeuralcanalSomiteendodermIntraembryoniccavityIntermediateNeuralcanalSomite---intermediatemesoderm:→kidneyandreproductivesystem---intermediatemesoderm:---lateralmesoderm:Intra-embryoniccoelom:→bodycavityparietalorsomaticmesoderm:→muscle,CT,parietallayerofpleura,peritoneumandpericardiumvisceralorsplanchnicmesoderm:→muscle,CTofdigestivetract,viscerallayerofpleura,peritoneumandpericardium---lateralmesoderm:ParietalmesodermvisceralmesodermIntra-embryoniccavityParietalvisceralIntra-embryon3.differentiationofendoderm:

primitivegut:→digestive,respiratoryandurinarysystem

foregutmidguthindgutCloacalmembraneoropharyngealmembrane3.differentiationofendoderm【醫(yī)學(xué)生物】組織胚胎學(xué)課件41.Embryonicperiodis

A.fromfertilizationtotheendofweek2

B.fromfertilizationtotheendofweek8

C.fromweek3totheendofweek8D.fromweek5totheendofweek8E.fromweek9untilbirth2.Howlongwillanindividualstayintheuterusofitsmother?

A.18weeks

B.28weeks

C.38weeks

D.48weeks

E.58weeksBC1.EmbryonicperiodisBC3.Whatispenetratedbyaspermatozoonduringtheprocessoffertilization

A.oogonium

B.primaryoocyte

C.secondaryoocyteD.primaryfollicleE.primordialfollicle4.Whichproteinisreceptorofspermatozoaonthezonapellucida?

A.ZP1

B.ZP2

C.ZP3

D.ZP4

E.ZP5C

C3.Whatispenetratedbyaspe5.Thetimeofimplantationis

A.from1st-2nddayto7th-8thday

B.from3rd-4thdayto9th-10thday

C.from5th-6thdayto11th-12thdayD.from7th-8thdayto13th-14thdayE.from9th-10thdayto15th-16thday6.Whichstructureisnotbelongtoearlyblastocyst?

A.trophoblast

B.zonapellucida

C.innercellmass

D.blastocoele

E.endodermC

E

5.Thetimeofimplantationis7.Whichisnotcorrectaboutimplantation

A.blastocystwillbeimbeddedintheendomytrium

B.zonapellucidadisappears

C.polartrophoblastsecretesproteinaseD.endomytriumisinproliferative