Deserpidine-hydrochloride-Harmonyl-hydrochloride-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEDeserpidinehydrochlorideCat.No.:HY-107339ACASNo.:6033-69-8Synonyms:Harmonylhydrochloride分?式:C??H??ClN?O?分?量:615.11作?靶點:Angiotensin-convertingEnzyme(ACE)作?通路:MetabolicEnzyme/Protease儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Deserpidinehydrochloride(Harmonylhydrochloride)?種抗??壓化合物，具有競爭性抑制?管緊張素轉(zhuǎn)化酶（ACE）的活性。Deserpidinehydrochloride通過與?管緊張素I競賽ACE，阻??管緊張素I轉(zhuǎn)化為?管緊張素II，從?降低?壓。Deserpidinehydrochloride也能夠減少由腎上腺?質(zhì)分泌的?管緊張素II誘導(dǎo)的醛REFERENCES[1].VarchiG,etal.Synthesisofdeserpidinefromreserpine.JNatProd.2005Nov;68(11):1629-31.[2].ZhangH,etal.Liquidchromatography/tandemmassspectrometrymethodforthequantificationofdeserpidineinhumanplasma:Applicationtoapharmacokineticstudy.JChromatogrBAnalytTechnolBiomedLifeSci.2009Oct1;877(27):3221-5.[3].FultonSC,etal.Comparisonoftheeffectivenessofdeserpidine,reserpine,andalpha-methyltyrosineonbrainbiogenicamines.FedProc.1976Dec;35(14):2558-62.[4].Liquidchromatography/tandemmassspectrometrymethodforthequantificationofdeserpidineinhumanplasma:ApplicationtoapharmacokineticstudyMcePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-5