第5章 逆合成分析法

1、精選精選ppt精選精選ppt精選精選ppt主要講授內(nèi)容主要講授內(nèi)容精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt 精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選pptFGACO2HOCH3OFridel - CraftsOCH3OOO精選精選pptPhO COOHPhPhMgBrO COOHOOO重接Phor重接FGAPhOHPhMgBrO合成子試劑精選精選ppt CHO OHPPh3OHC OHWittig精選精

2、選ppt 重接OOHOHC OHFGIOO BayerVilligerOFGAOCOOEt COOEt OEtO 重接FGICOXXOCDielsAlderOOO精選精選ppt精選精選ppt精選精選ppt CH2CH2CH3COHH精選精選pptCH2CH2CH3COHHabCOHHCH2 CH2 CH3a1 1a aCH2CH2CH3COHHPhMgBrCOCH2CH2CH3H2 2a aCH2CH2CH3COHH精選精選pptCOHHCH2 CH2 CH3bCOCH2CH2CH3NaBH4COCH2CH2CH3c c合成子合成子CH2CH2CH3COCH2CH2CH3COCl精選精選ppt

3、MgBrHCCH2CH2CH3OEt2OCOMgBrHCH2 CH2 CH3NH4ClH2OCOHHCH2 CH2 CH3CH3CH2CH2COOHSOCl2CH3CH2CH2COClC6H6AlCl3COCH2CH2CH3NaBH4CH3OHCOHHCH2 CH2 CH3精選精選ppt b badis bdis aCH3OHCH3OCH3OHcdH3CCH3MgIMgBrBrOHCH3OHCH3OCH3CH3精選精選pptCOOHFGIFGAbac COOEt COOEt MgBrCO2 BrFGI OH MgBr CHO MgBr CHOdis cdis bFGICOOEtCOOEt Br

4、dis bdis c BrCOOEtdis c Br COOEt COOEtdis b Br COOEt COOEtdis a精選精選pptDACOOMeCOOMeCOOMeor Lewis acidCOOMe精選精選pptdisCHOCHOH2NMeOCH3CH3ONMeNROdisOH2NRCH2OCH2O精選精選pptOF FG G A AO OHO OHOOOOOOOOMeONaMeOHO精選精選ppt HC XX XOXCXX = OR, NHR, SR 等精選精選pptOHCOOH OOOCOOHCH2(CO2Et)2(1) EtONa(2) nC7H15Br(CO2Et)2CHC

5、7H15n(2) O(1) EtONaOOEtO2C (1) HO, H2O(2) H , OO精選精選ppt dis aOOXdis bOOXOba精選精選ppt精選精選ppt精選精選ppt精選精選ppt (CH3CO)2OAlCl3COCH3EtMgBrEt2OH3OC CH2CH3CH3OH精選精選pptCl2ClMgEt2OMgClCH3COCH3H3OCCH3CH3OH精選精選ppt精選精選pptB Br rM M g gT T H H F FM M g gB Br rC C O O O O E Et tC C O O O O E Et tH H3 3O OT T H H F FC

6、C O O H H精選精選pptBrMgTHFMgBrOH3OOHHBrBr精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt 精選精選ppt ()精選精選ppt 精選精選ppt 精選精選ppt精選精選ppt精選精選pptOOdisHOHO+OFGIOHHOdisHCCH+2 HCHOOHHOHCCH+OH2 HCHOH2Pd / BaSO4HOHOHClOOO精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt作業(yè)作業(yè)： 由逆合成分析法，推導(dǎo)下列化合物的合成路線。由逆合成分析法，推導(dǎo)下列化合物的合成路線。精選精選ppt()：精選精選ppt精選精選ppt精選精選ppt精選精選ppt精選精選ppt( ) ()精選精選ppt精選精選pptOdisOOdisO+OClONHNOClNOH3OOO:BO精選精選ppt精選精選pptCH2=CHCOCH3CH3COCH2COOEtNaOC2H5精選精選ppt精選精選ppt ()精選精選ppt精選精選ppt精選精選ppt精選精選ppt親核合成子的親核合成子的合成等效體合成等效體disO精選精選pptH3OHBr精選精選ppt作業(yè)：作業(yè)： 由逆合成分析法，推導(dǎo)下列化合物的合成路