Lauric-acid - Endogenous Metabolite - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELauric acidCat. No.: HY-Y0366CAS No.: 143-07-7分式: CHO分量: 200.32作靶點(diǎn): Endogenous Metabolite; Bacterial作通路: Metabolic Enzyme/Protease; Anti-infection儲(chǔ)存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect f

2、romlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 250 mg/mL (1248.00 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 4.9920 mL 24.9601 mL 49.9201 mL5 mM 0.9984 mL 4.9920 mL 9.9840 mL10 mM 0.4992 mL 2.4960 mL 4.9920 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥

3、式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (10.38 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (10.38 mM); Clear solutionBIOLOGI

4、CAL ACTIVITY1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE物活性 Lauric acid是中鏈脂肪酸，有很強(qiáng)的抗菌活性，對(duì) P. acnes，S.aureus，和 S. epidermidis 的 EC50 值分別為2，6，4 g/mL。IC50 & Target Human Endogenous MetaboliteREFERENCES1. Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acnevulgaris. J Invest Dermatol. 2009 Oct;129(10):2480-8.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;