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1、DearPleaseconstractmyPSwithin850950words al S Asagirl whohad anttackprettynearlydeprivedthelifeoffathers, I have more enthusiasm for studying genetic dissection of human n most of others. Master and undergraduate study provide DearPleaseconstractmyPSwithin850950words al S Asagirl whohad anttackprett
2、ynearlydeprivedthelifeoffathers, I have more enthusiasm for studying genetic dissection of human n most of others. Master and undergraduate study provide me sound base inbios istics, molecular ive genetics.Academic andactivities develop my communication skills, cooperation and leadership. goal orien
3、ted,hardworkingandcooperative,Ibe veIamanidealcandidateforyour The rRecent revolutionary in genomics , such as Human Projects, HapMap Project,andhigh-throughputsequencing technology,have led o a genome era. It makesThese developments have made the detection disease-causing genes in the scope of whol
4、e a human sible and opens opened extraordinary opportunities for us scientists to unravel the underlying genetic mechanisms of complex diseases. To grasp these opportunitiesavail of sibilities, Iwas determined to applyamapplying forPh.D. studyin and s istical genetics at complex traits.X University
5、with a focus on genetic dissection I completed my mater he lab of ivegenetic which is by ChairmanofAnimalGeneticsandBreedingSociety,X Our lab is national known for its research strengths in s isticalgenetics. from the dense academic atmosphere and extensive learning , I have groundedmyselfof 18, whe
6、n I was on at an evening class, my sistercalled me and told t our father was sending sent to the hospital for because of a tack. . timeever,Iwasbecameawareofthefragilityoflife.Drivenbyinnerto unravel genetic puzzle ofcommon diseases, I rsonalt me to make sible use of the any available learning oppor
7、tunitiesto eticimproveandpreparemyselfasapotential hisof common diseases. For le, Mmy strong graduate academic performance graduate academic records (GPA: 3.85/4.0, ing: 5/105) reflected reflects withwhich Ibecameabsorbed myhedisciplineBesidesAdditionally, I took active participateparticipated in ac
8、ademicchasseminarsandjournalJournalhelatterFormatted:Formatted:Indent:Left: Formatted:Normal,line: Formatted:I was awarded “thethe “ bBest research Research practicePractice” recognition,” and “the bBest r r presen ionPresen ion” title,” by our journal during my during year of master. I also wonand
9、the “Research Achievement year of I was awarded “thethe “ bBest research Research practicePractice” recognition,” and “the bBest r r presen ionPresen ion” title,” by our journal during my during year of master. I also wonand the “Research Achievement year of my Masters These acknowledgments illustra
10、temyexcellentforstandoutinresearchingperformance Though these records demonstrate myexcellence as a student thirsty forto me, theOverall, myy biggest academic gain t my research ability was gre improved through graduate study. The project I joined was “Genomic Potential was involved ive Traits of Sw
11、ine” which consisted of several sub projects. I one a sub particular project named called “Genomic Potential Improving Reproductive Traits of swineSwine,” a sub-branch of a larger effort, “Genomic Potential in Improving task duties included two major parts. Oneive Traits ofSwine.” . My , I was taske
12、d with estimating relevant genetic parameters estimating and asso tion ysis yzing the impact of environmental factors on reproductive traits. This work provided reference referential data for the following experimental design. The other one wasmy other duty, looking for non-invasive biomarkers of pr
13、egnancy and detection return causingdetecting t caused estrus to return. My experiment based on a case-control microarray study design. , and ultima y, sible eraction network, based on pre-defined pathway information and genes present in the GO terms, was built up based on pre defined pathway inform
14、ation and genes present in the GO terms. Currently, I am working on data pro sing for my hese hands-on projects, I was skilled in usingskillfullyused Excel to raw data, using SAS to do ysis, using and DMU to estimate heritability. lly, I was familiar with ysis based on R andpublicdatabases,suchasSAM
15、ysisofMicroarray),Clustering, GO ent and Pathway ysis. In addition, thehaving had experience of extractionextracting DNA and RNA from thousands different e les, I became pretty hese basic experiments as well as someeven more sophisticated biological experiments, including like real-time RT-PCR, bisu
16、lhite treatment, and pyrosequencing.imate contact with complex traits impressed me by its involving multiple eraction with one anotherand environment,whichspatial and temporal specific eraction network. Nowadays, Genome Wide tion Studies (GWAS) are prevailing. Its feasibility is demonstrated Formatt
17、ed:identificationmanynoveltaffectsusceptibilitytosome commonsuchasbreastcancer.Thereare lotsoffurtherstudies ofGWASattracting mesuchbiology based ing of complex phenomena by making using of databases,approachesstasisstudyandpopulationMaster and undergraduate study not only equips me nowledge, develo
18、ps my identificationmanynoveltaffectsusceptibilitytosome commonsuchasbreastcancer.Thereare lotsoffurtherstudies ofGWASattracting mesuchbiology based ing of complex phenomena by making using of databases,approachesstasisstudyandpopulationMaster and undergraduate study not only equips me nowledge, dev
19、elops my comprehensive academic studies, I also iveina such variety of extracurricular activities, ,engagements which developed communication anizational ability abilities, and experience I want to emphasize was when I was aFor y junior year, as was the leader ofa studentanizationcalledus to CareerT
20、ransition for short, borrowing ideas from 4 H Youth anization),. I led the club anize a practical training project which attractedfor students taking part in. Our projects practice spots covered a wide geographical area,fromNorthernChinatoSouthernpartChina.Itawfullychallengedmycapability; to plan pr
21、epare and prepare the whole project, such asthis initiative, I had to looking for sponsors, publicitypublicize, contacting with practice sites, and recruitingparticipants and o different teams, nks to the making by all of my club partners, we eventually managed to arrange everyone their itions. And
22、our efforts paid off. Three teams were recognized as “CAU Outstanding Practice Teams.”. Moreover, Wwe also got awarded a funding grant of 20,000 RMB from our college foruniversity in twe might publishing publish books on what we did and what we learned. As anizer,thebestlessonIlearnedwas howtoeffici
23、entlyutilizeandallocate lly human . This lesson helped me a lot when I named as one of the student administrators of our my lab. , and I am certai continue to benefit my future research work, I be ve.t Finally, Icompleted myMasters he ivegenetics lab Animal Genetics was guided by X Qin, chairman of
24、the Breeding Society. The Societys lab is nationally renowned for its research ins istical genetics. Benefiting fromthe rigors of this particular environment,thenextlogicalnmyacademicquestistopursue myAcademic experience and extracurricular activities qualify me as a potential researcher in the fiel
25、d of s istical genetics. However, sophisticated knowledge in bios istics and systematic research training is what I aspire need in order to fulfillmy ultimate goal. As one of your countrysAmericas est graduate programs biology, your Human and S istical Genetics Ph.D. ensively appeals to me for its s
26、tandout inemphases on genomics, genetics, and s istics. Your More importantly, your research focus and e encouragement of students withFormatted:diversecultureandbackgroundsarethemostimportantfactorsformyMygoal,as synchronisticwithyourobjectivegoes,istopreparefuturescientistswith s istical and human
27、 genetic methods for the study of human disease. Im I eagertofurth via your ursue furtherstudyanddevelopmyresearchhis field . Mybloodboils atIam excited bythe very thoughtof my futurean outstanding researcher devoting myself to dissection dissecting human complex The author has ed a very thorough an
28、d diversecultureandbackgroundsarethemostimportantfactorsformyMygoal,as synchronisticwithyourobjectivegoes,istopreparefuturescientistswith s istical and human genetic methods for the study of human disease. Im I eagertofurth via your ursue furtherstudyanddevelopmyresearchhis field . Mybloodboils atIa
29、m excited bythe very thoughtof my futurean outstanding researcher devoting myself to dissection dissecting human complex The author has ed a very thorough and al s brimming n array of life andal reflection on those events. al s ement down to fit As the author requested, I significantly edited desire
30、d word-count range. Overall, I t al s ement is conciseandappealingsubsequentoftheseThe author will t I deleted paragraph of her s t is not tot the paragraph was ineffective in of itself; the paragraph was ering the overall structure of al s s ement, the author employed TWO roductory paragraphs, onedeletedserving as of al s ement as a whole, and otherthe roducing the authors educational aims. The paragraph isbetterbecauseitemphasizes educationanddoesnotforfeit theofals ementthebeginning,asthedeletedparagraphsee
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