Metamizole-sodium-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEMetamizolesodium(Standard)Cat.No.:HY-B1279ARCASNo.:68-89-3分?式:C??H??N?NaO?S分?量:333.34作?靶點(diǎn):COX;Apoptosis作?通路:Immunology/Inflammation;Apoptosis儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Metamizole(sodium)(Standard)Metamizole(sodium)的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Metamizolesodium(Dipyrone)?種有?服活性的環(huán)氧合酶(COX)抑制劑。Metamizolesodium可抑制細(xì)胞增殖，促進(jìn)細(xì)胞凋亡。Metamizolesodium有抗炎和抗氧化活性。Metamizolesodium?種解熱鎮(zhèn)痛解痙劑。Metamizolesodium可?于緩解各種疼痛的研究。IC50&TargetCOX-3[2]REFERENCES[1].DPierreSC,etal.Inhibitionofcyclooxygenasesbydipyrone.BrJPharmacol.2007Jun;151(4):494-503.[2].DeLuna-BertosE,etal.Therapeuticdosesofnonsteroidalanti-inflammatorydrugsinhibitosteosarcomaMG-63osteoblast-likecellsmaturation,viability,andbiomineralizationpotential.ScientificWorldJournal.2013Sep19;2013:809891.[3].MalsyM,etal.Effectsofmetamizole,MAA,andparacetamolonproliferation,apoptosis,andnecrosisinthepancreaticcancercelllinesPaTu8988tandPanc-1.BMCPharmacolToxicol.2017Dec6;18(1):77.[4].ZajaczkowskaR,etal.Metamizolerelievespainbyinfluencingcytokinelevelsindorsalrootgangliainaratmodelofneuropathicpain.PharmacolRep.2020Oct;72(5):1310-1322.[5].InceI,AksoyM,etal.AComparativeInvestigationoftheAnalgesicEffectsofMetamizoleandParacetamolinRats.JInvestSurg.2015Jun;28(3):173-80.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792/p>