Lincomycin-hydrochloride-hydrate-Lincomycin-hydrochloride-monohydrate-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemELincomycin hydrochloride hydrateCat. No.: HY-B1358CAS No.: 7179-49-9Synonyms: Lincomycin hydrochloride monohydrate分式: CHClNOS分量: 461.01作靶點(diǎn): Bacterial作通路: Anti-infection儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-2

2、0C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 100 mg/mL (216.92 mM)H2O : 50 mg/mL (108.46 mM; Need ultrasonic)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.1692 mL 10.8458 mL 21.6915 mL5 mM 0.4338 mL 2.1692 mL 4.3383 mL10 mM 0.2169 mL 1.0846 mL 2.1692 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇

3、合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (5.42 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in sa

4、line)1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (5.42 mM); Clear solution3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (5.42 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Lincomycin hydrochloride hydrate (Lincomycin hydrochloride monohydrate)窄譜抗素, 具有與紅霉素相似的效, 對(duì)蘭陽性球

5、 具有很好的作效果, 主 抑制細(xì) 細(xì)胞蛋質(zhì)的合成。戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Chemosphere. 2019 Mar.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. MACLEOD AJ, et al. LINCOMYCIN: A NEW ANTIBIOTIC ACTIVE AGAINST STAPHYLOCOCCI AND OTHER GRAM-POSITIVECOCCI: CLINICAL AND LABORATORY STUDIES. Can Med Assoc J. 1964 Nov 14;91

6、:1056-60.2. Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol andlincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820