Noscapine-S-R-Noscapine-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemENoscapineCat. No.: HY-13716CAS No.: 128-62-1Synonyms: (S,R)-Noscapine分式: CHNO分量: 413.42作靶點(diǎn): Sigma Receptor; Autophagy作通路: GPCR/G Protein; Neuronal Signaling; Autophagy儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20

2、C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 30 mg/mL (72.57 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.4188 mL 12.0942 mL 24.1885 mL5 mM 0.4838 mL 2.4188 mL 4.8377 mL10 mM 0.2419 mL 1.2094 mL 2.4188 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥式選擇

3、適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.05 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (6.05 mM); Clear solution1/2 Mas

4、ter of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 Noscapine種服咳藥, 主要通過(guò)其 受體激動(dòng)劑活性調(diào)節(jié), 且Noscapine具有抗癌活性。戶(hù)使本產(chǎn)品發(fā)表的科研獻(xiàn) Patent. US20180263995A1.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Yang Y, et al. CYLD Regulates Noscapine Activity in Acute Lymphoblastic Leukemia via a Microtubule-Dependent Mechanism.Theranostics. 2015 Mar 2;5(7):656-666.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;F