Eicosapentaenoic-acid-ethyl-ester-AMR-101-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEicosapentaenoic acid ethyl esterCat. No.: HY-B0747CAS No.: 86227-47-6Synonyms: AMR-101; Ethyl eicosapentaenoate; EPA ethyl ester分式: CHO分量: 330.5作靶點(diǎn): Others作通路: Others儲(chǔ)存式: 4C, stored under nitrogen* In solvent : -80C, 6 months;

2、-20C, 1 month (stored undernitrogen)溶解性數(shù)據(jù)體外實(shí)驗(yàn) Ethanol : 50 mg/mL (151.29 mM; Need ultrasonic)DMSO : 33.33 mg/mL (100.85 mM; Need ultrasonic)H2O : 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.56 mM); Suspended solution; Need ultrasonic2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solu

3、bility: 2.5 mg/mL (7.56 mM); Suspended solution; Need ultrasonic1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (7.56 mM); Clear solution4. 請依序添加每種溶劑： 10% EtOH 40% PEG300 5% Tween-80 45% salineSolubility: 5 mg/mL (15.13 mM); Clear solution5.

4、請依序添加每種溶劑： 10% EtOH 90% (20% SBE-CD in saline)Solubility: 5 mg/mL (15.13 mM); Suspended solution; Need ultrasonic6. 請依序添加每種溶劑： 10% EtOH 90% corn oilSolubility: 5 mg/mL (15.13 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Eicosapentaenoic acid ethyl ester (AMR-101)種 -3 脂肪酸劑。REFERENCES1. Jacobson TA. A ne

5、w pure -3 eicosapentaenoic acid ethyl ester (AMR101) for the management of hypertriglyceridemia: the MARINEtrial. Expert Rev Cardiovasc Ther. 2012 Jun;10(6):687-695.2. Bays HE, et al. Eicosapentaenoic acid ethyl ester (AMR101) therapy in patients with very high triglyceride levels (from theMulti-center,plAcebo-controlled, Randomized, double-blINd, 12-week study with an open-label ExtensionMARINE trial). Am J Cardiol. 2011 Sep1;108(5):682-690.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-37