豬皮膚疾病的鑒別診斷課件

豬皮膚疾病的鑒別診斷課件1豬皮膚疾病的鑒別診斷豬皮膚疾病的鑒別診斷2表皮層真皮層基底層：主要為角質(zhì)化細(xì)胞棘層：為多邊形細(xì)胞粒層：為扁平細(xì)胞角質(zhì)層：為角質(zhì)化細(xì)胞乳頭層網(wǎng)層皮膚的結(jié)構(gòu)另：鼻還有透明層均由結(jié)締組織組成，分布有血管、神經(jīng)、淋巴管及相關(guān)的表皮附件表皮層真皮層基底層：主要為角質(zhì)化細(xì)胞棘層：為多邊形細(xì)3皮膚的功能維持體液、電解質(zhì)及大分子物質(zhì)的平衡防御化學(xué)因素、物理因素、微生物的損害或侵入感受觸覺(jué)、壓覺(jué)、痛覺(jué)、癢覺(jué)及溫度變化免疫調(diào)節(jié)維持體溫皮膚的功能維持體液、電解質(zhì)及大分子物質(zhì)的平衡防御化學(xué)因素、物4豬的皮膚病病因感染性非感染性細(xì)菌性病毒性真菌性寄生蟲(chóng)性環(huán)境性營(yíng)養(yǎng)性遺傳性腫瘤性雜病豬的皮膚病病因感染性非感染性細(xì)菌性病毒性真菌性寄生蟲(chóng)性環(huán)境性5細(xì)菌性：滲出性皮炎、鏈球菌病、耳壞死、螺旋體病、面部壞死、膿腫、丹毒、巴氏桿菌病、乳腺炎、水腫病、炭疽、惡性水腫病毒性：豬痘、豬水皰病、水皰性口炎、水皰疹、豬細(xì)小病毒病、自發(fā)性水皰病、豬瘟、非洲豬瘟真菌性：小孢子菌病、毛癬菌病、皮膚念珠菌病寄生蟲(chóng)性；疥螨病、蠕螨病、虱、蚤、蚊、蠅細(xì)菌性：滲出性皮炎、鏈球菌病、耳壞死、螺旋體病、面部壞死、膿6環(huán)境性：曬斑、光敏反應(yīng)、皮膚壞死、黏液囊炎、硬皮病、跛行及腳病變營(yíng)養(yǎng)性：角化不全、脂肪酸缺乏、碘缺乏、核黃素缺乏、泛酸缺乏、生物素缺乏、VA、VC、VE缺乏遺傳性：玫瑰糠疹、增生性皮炎、上皮增殖不全腫瘤性：黑素瘤、橫紋肌瘤、淋巴管瘤、乳頭狀瘤、纖維瘤、血管瘤、汗腺腺瘤、息肉雜?。浩ぱ啄I病綜合征環(huán)境性：曬斑、光敏反應(yīng)、皮膚壞死、黏液囊炎、硬皮病、跛行及腳7皮膚病的鑒別診斷頭頸步斑點(diǎn)、水泡、膿庖，脂溢性滲出物（皮脂溢），哺乳仔豬和斷奶仔豬，尤其眼周圍滲出性皮炎膿皰痂，糜爛，結(jié)痂，膿腫鏈球菌病斑塊，膿皰，結(jié)痂，脫毛，伴有瘙癢疥螨病膿皰，糜爛，壞死，哺乳仔豬眼下，頰部，唇結(jié)痂面部壞死眼周圍，結(jié)膜，額部水腫，多見(jiàn)于斷奶仔豬和青年育肥豬水腫病頭、咽部水腫惡性水腫鼻、面部及頸部變?yōu)榧t色至紫紅色敗血癥皮膚病的鑒別診斷頭頸步斑點(diǎn)、水泡、膿庖，脂溢性滲出物（皮脂溢8頭頸步母豬皮膚散在潰瘍、下頜骨處結(jié)痂褥瘡鼻、唇、口、舌部有水泡，膿皰，壞死口蹄疫、豬水皰病、水皰疹，水泡性口炎，細(xì)小病毒病，自發(fā)性水泡病水泡，潰爛，黑痂豬痘頭頸步母豬皮膚散在潰瘍、下頜骨處結(jié)痂褥瘡鼻、唇、口、舌部有水9耳部仔豬耳尖和耳廓后緣黑色壞死，潰瘍耳壞死，沙門(mén)氏菌病，丹毒育肥豬耳廓基部深度潰瘍，常為雙側(cè)性潰瘍性螺旋體病，敗血癥，豬瘟，非洲豬瘟，曬斑斑塊，內(nèi)耳有棕色或灰色痂膜，耳震顫，瘙癢，成年豬可見(jiàn)灰色厚痂疥螨病斑點(diǎn)，膿皰，黑痂滲出性皮炎，鏈球菌病圓形斑點(diǎn)，小鱗屑，耳后和頸部變?yōu)榉凵良t色癬菌?。ㄐ℃咦泳。┒孔胸i耳尖和耳廓后緣黑色壞死，潰瘍耳壞死，沙門(mén)氏菌病，丹毒10背部角化癥，脊柱兩側(cè)有干鱗屑，部分脫毛必需脂肪酸、VA、VC、VE、鋅等缺乏新生仔豬無(wú)上皮（表觀紅色、光亮、面積大）疥螨病、上皮增殖不全母豬最后肋骨的脊柱上部、腰部膿腫，壓迫性壞死褥袍，因產(chǎn)房?jī)?nèi)分娩時(shí)壓迫豬欄的板條或尖頭處背部角化癥，脊柱兩側(cè)有干鱗屑，部分脫毛必需脂肪酸、VA、VC11肩部母豬肩胛骨處皮膚呈大面積深度散在潰瘍，壞死，結(jié)痂多見(jiàn)于體況差褥瘡，因在太硬或鋼筋網(wǎng)結(jié)構(gòu)地面分娩，攝入能量太少肩部母豬肩胛骨處皮膚呈大面積深度散在潰瘍，壞死，結(jié)痂多見(jiàn)于體12腹部紅斑，膿皰，深棕色痂片，滲出滲出性皮炎，鏈球菌病，疥螨病，念珠菌病，生物素缺乏紅斑，圓形，鉆石樣紅色斑塊，常伴有中央壞死，發(fā)熱，厭食，關(guān)節(jié)炎丹毒繩索勒傷樣丘疹，蜀黍紅疹項(xiàng)圈，鱗片及鱗屑（3-14周齡豬）玫瑰糠疹粉色至圓形斑點(diǎn)，外周有鱗屑或痂片癬菌?。ㄐ℃咦泳?，毛癬菌?。└共考t斑，膿皰，深棕色痂片，滲出滲出性皮炎，鏈球菌病，疥螨病13腹部丘疹、厚痂、有裂紋，滲出物鋅缺乏（角化不全），增生性皮炎，滲出性皮炎水泡，膿皰，黑痂，病變部位中央凹陷，周圍呈圓形隆起豬痘，急性乳房炎泌乳母豬病變處有紅斑，尤其是仔豬胸部乳頭，后乳頭有紅色或黑色斑塊（痂）產(chǎn)房衛(wèi)生差，地面粗糙所致的外傷和感染腹部丘疹、厚痂、有裂紋，滲出物鋅缺乏（角化不全），增生性皮炎14后腹部及肋腹部紅斑，圓形或鉆石樣紅色斑塊，伴有中央壞死、發(fā)熱、厭食、關(guān)節(jié)炎丹毒丘疹，水泡，膿皰，鱗屑，結(jié)痂，皮脂溢滲出性皮炎，鏈球菌病膿皰，鱗屑，皮膚嚴(yán)重卷曲，脫毛，結(jié)痂，伴有角化過(guò)度疥螨病，煙酸、泛酸、核黃素、VA缺乏肋腹部有紅斑、糜爛或潰瘍肋部咬傷丘疹、圓形樣斑塊，蜀黍紅疹項(xiàng)圈，鱗屑（3-14周齡）豬玫瑰糠疹大小不一的粉色至圓形斑點(diǎn)，外周有鱗片或結(jié)痂癬菌?。ㄐ℃咦泳?，毛癬菌?。┖蟾共考袄吒共考t斑，圓形或鉆石樣紅色斑塊，伴有中央壞死、發(fā)熱15后腹部陰囊，外陰和會(huì)陰部紅斑敗血癥、曬斑尾壞死，潰瘍，膿腫（育肥豬）咬尾髖骨處大面積散在潰瘍，壞死，結(jié)痂（成年豬）褥瘡紅斑，黑色壞死，多見(jiàn)于陰囊和外陰部皮炎/腎病綜合征圓形隆起的小疹塊，蕁麻疹樣反應(yīng)昆蟲(chóng)叮咬，蠅、蚊、虱后腹部陰囊，外陰和會(huì)陰部紅斑敗血癥、曬斑尾壞死，潰瘍，膿腫（16腿（肢）紅斑，皮膚變?yōu)榧t色至紫色，多見(jiàn)于后踝周圍敗血癥丘疹，繩索勒傷樣斑塊，蜀黍紅疹項(xiàng)圈，鱗片及鱗屑，股中部及腿部有鱗屑（3-14周齡豬）玫瑰糠疹丘疹，厚痂，有裂紋，乳頭狀瘤鋅缺乏（角化不全），滲出性皮炎新生仔豬無(wú)上皮（表觀紅色、光亮、面積大）上皮增殖不全關(guān)節(jié)（后踝、肘、球節(jié)、坐骨關(guān)節(jié)）處皮膚過(guò)度纖維化，有潰瘍硬皮病，黏液囊炎哺乳仔豬腕，特別是后踝處皮膚壞死產(chǎn)房地面太硬所致的外傷腿（肢）紅斑，皮膚變?yōu)榧t色至紫色，多見(jiàn)于后踝周圍敗血癥丘疹，17肢遠(yuǎn)端、冠狀帶、腳厚，干痂，裂紋深角化不全，增生性皮炎，滲出性皮炎，疥螨病冠狀帶及附指（趾）周圍有水泡，膿皰，糜爛，跛行口蹄疫、豬水皰病、水泡性口炎，水皰疹，細(xì)小病毒病，自發(fā)性水泡病膿腫，有滲出物，冠狀帶腫脹蹄感染引起的Bush腳蹄壁增厚，水平嵴及與冠狀帶平行增生性皮炎肢遠(yuǎn)端、冠狀帶、腳厚，干痂，裂紋深角化不全，增生性皮炎，滲出18滲出性皮炎(

ExudativeEpidermitisorGreasypigdisease)Exudativeepidermitisisageneralizeddermatitisthatoccursin5-to60-day-oldpigsandischaracterizedbysuddenonset,withmorbidityof10-90%andmortalityof5-90%.Theacuteformusuallyaffectssucklingpiglets,whereasachronicformismoremonlyseeninweanerpigs.Ithasbeenreportedfrommostswine-producingareasoftheworld.

滲出性皮炎(ExudativeEpidermitiso19豬皮膚疾病的鑒別診斷課件20滲出性皮炎滲出性皮炎21Thegeneralisedform.

Thegeneralisedform.22Alocalisedlesionofgreasypigdisease.Thismaybecannibalised.Alocalisedlesionofgreasyp23EXUDATIVEEPIDERMITISSubacuteexudativeepidermitisaffectingtheface,limbsandventralabdomentinsucklingpiglets.

EXUDATIVEEPIDERMITIS24

EXUDATIVEEPIDERMITISExudativeepidermitis.Thisyoungpigshowsthecharacteristic?greasy?lesionontheventralabdomen.

25

EXUDATIVEEPIDERMITISChronicexudativeepidermitisovertheentirebodyinweanerpigapproximately5weeksold.

26鏈球菌病PigsKissing鏈球菌病PigsKissing27鏈球菌病豬鏈球菌病是一種人畜共患的急性、熱性傳染病，由C、D、E及L群鏈球菌引起的豬的多種疾病的總稱。表現(xiàn)為急性出血性敗血癥、心內(nèi)膜炎、腦膜炎、關(guān)節(jié)炎、哺乳仔豬下痢和孕豬流產(chǎn)等。

豬鏈球菌感染不僅可致豬敗血癥肺炎、腦膜炎、關(guān)節(jié)炎及心內(nèi)膜炎，而且可感染特定人群發(fā)病，并可致死亡，危害嚴(yán)重。

豬鏈球菌病可以通過(guò)傷口、消化道等途徑傳染給人，這種病原體早已長(zhǎng)期存在豬群身上，因?yàn)橥饨绛h(huán)境發(fā)生的變化使得病原體發(fā)生變異，從而突破種群障礙，開(kāi)始從豬傳播給人。鏈球菌病豬鏈球菌病是一種人畜共患的急性、熱性傳染病，由C、D28豬皮膚疾病的鑒別診斷課件29豬皮膚疾病的鑒別診斷課件30豬皮膚疾病的鑒別診斷課件31螺旋體病leptospirosisLeptospirosisisadiseaseofdomesticanimalscausedbybacteriabelongingtothegenusLeptospira.Theseorganismshaveaworldwidedistributionandcauseeconomiclossprimarilythroughreproductivewastage.Lossesaregreatestinanimalpopulationskeptundertheintensivefarmingsystemsfoundinthedevelopedworld.Specificstrainsaremaintainedbydifferentdomesticanimalhosts,e.g.serovarhardjoismaintainedbycattleandserovarbratislavaismaintainedbypigs.Leptospirosisisazoonosiswhichprimarilyaffectspeopleworkinginagricultureandrelatedoccupations.螺旋體病leptospirosisLeptospirosis32豬皮膚疾病的鑒別診斷課件33

34豬皮膚疾病的鑒別診斷課件35豬皮膚疾病的鑒別診斷課件36豬皮膚疾病的鑒別診斷課件37

38丹毒Swineerysipelasisaninfectioncharacterizedbydiamondshapedskinlesionsandinthechronicform,byvegetativeendocarditisandarthritis.ItiscausedbyErysipelothrixrhusiopathiae.丹毒Swineerysipelasisaninfec39ErysipelothrixrhusiopathiaeErysipelothrixrhusiopathiae40Erysipelothrixrhusiopathiae,Gram'sstain,highpower.Vegetativeendocarditislesion,showingthegram-positivefilamentstypicalofthisorganism.Erysipelothrixrhusiopathiae,41Columbiaagar,48h,aerobně.

Columbiaagar,48h,aerobně.42Antemortemfindings:HighmorbidityFeverinacutestagesConjunctivitisandvomitinginsomecasesBrightandalert,squealinginpainonmovementPigislethargicandstopseatingRaisedredandedematousrhomboidwheals(acuteandchronicforms)SloughingofskinintheareaoftherhomboidlesionSwollenjointsandlameness(chronicstage)SuddendeathinexcitedanimalsAntemortemfindings:43豬皮膚疾病的鑒別診斷課件44急性型Acutetype(麻疹型):全身皮膚に形成された菱形丘疹

急性型Acutetype(麻疹型):全身皮膚に形成さ45臀部皮膚に形成された隆起した淡紅色の菱形皮疹臀部皮膚に形成された隆起した淡紅色の菱形皮疹46SWINEERYSIPELASAcutesevereskinformofswineerysipelaswithextensivesmallraisedpink/redlesionssomedevelopingdarkscabs.SWINEERYSIPELAS47Acuteswineerysipelas,notethetypicalraisedpinklesionswithdiamondshapeddarkred/blackcentralareas.Acuteswineerysipelas,notet48Erysipelasskinlesions,close-up.Erysipelasskinlesions,close49Swineerysipelas.Diamondshapedskinlesions.Swineerysipelas.Diamondshap50慢性型Chronictype(関節(jié)炎型):関節(jié)炎のため起立困難を呈する豚

慢性型Chronictype(関節(jié)炎型):関節(jié)炎のため51ErysipelasrhomboidlesionsonadolphinskinErysipelasrhomboidlesionson52

Erysipelasistransmittedbydirectcontactwithinfectedanimalsortheirexcreta.Thephotoshowsthehandofaninfectedhandler.Erysipelasistransmittedby53ResolvingcellulitiscausedbyErysipelothrixrhusiopathiaefollowingtreatmentwithdoxycyclineandciprofloxacin.Resolvingcellulitiscausedby54VesicularstomatitisViraldiseaseofswine,cattle,horsesandoccasionallyman.ThediseaseiscausedbytwoantigenicallydistincttypesofvirusnamelyIndianaandNewJerseytypes.Vesicularstomatitisinswineismostmonlymanifestedbysnoutandfootlesions.VesicularstomatitisViraldise55Antemortemfindings:Incubation2–4daysFeverLesiononthetongue(Fig.)andsnoutLesionintheinterdigitalspaceorcoronarybandRefusaloffoodbutacceptanceofwaterWeightlossLamenessandexungulationAntemortemfindings:56"Vesicularstomatitisvirus,purifiedfromaninfectedcellculture.Thisisanimportantpathogenicvirusofcattle,causingfeverandvesiclesinthemouthandonthefeet.Negativelystainedvirions:notethattheyareclearly"bulletshaped"justlikerabiesvirus.Magnificationapproximatelyx40,000.""Vesicularstomatitisvirus,p57Vesicularstomatitis.Detachmentofepitheliumofthepigtongue.Vesicularstomatitis.Detachme58Blanchedareasonthehardpalate,dentalpadandgums.Blanchedareasonthehardpal59Swinevesiculardisease(SWD)Acontagiousviraldiseaseofswineclinicallyindistinguishablefromvesicularstomatitis,footandmouthdiseaseandvesicularexanthemaofswine.Antemortemfindings:Incubation2–4daysFever40–41°CSnout(Fig),oralandfeetvesicularlesionsLamenessSwinevesiculardisease(SWD)A60Earlylesionsoncoronarybandoffoot.Earlylesionsoncoronaryband61Oldlesionsonfootwithpartialseparationofhoof.Oldlesionsonfootwithparti62Oldlesionsonrecoveredpigshowingbandinggrowingoutofhoof.Oldlesionsonrecoveredpigs63Swinevesiculardisease.Snoutvesicularlesion.Swinevesiculardisease.Snout64Vesicularlesionsonsnout.Vesicularlesionsonsnout.65Recentlyrupturedblisteronrimofsnout.Recentlyrupturedblisteronr66Recentlyrupturedblisteronfoot.Recentlyrupturedblisteronf67Separationofhornfollowingruptureofblister.Separationofhornfollowingr68Rupturedvesicleonsnoutandtongue.Rupturedvesicleonsnoutand69Lesionsoncoronaryband,bulbofheelandsupernumerarydigit.Lesionsoncoronaryband,bulb70Recentlyrupturedvesicleoninterdigitalspace.Recentlyrupturedvesicleoni71Rupturedvesiclesoncoronaryband.Separationofbands.Rupturedvesiclesoncoronary72Vesicularexanthemaofswine(VES)Anacute,contagious,viraldiseaseofswinemanifestedbytheformationofvesicles.VesicularexanthemaisindistinguishablefromtheotherswinediseasessuchasFMD,VSandSVD.Vesicularexanthemaofswine(73Antemortemfindings:Incubation:2–4daysLargenumberofhogsareaffected.HeavymortalityinsucklingpigsBlotchyrashinunpigmentedskin(exanthema)Vesiclesonthesnoutandinthemouth.RupturedvesiclesresultinerosionsLossofweightWalkingontheirknees(Fig.122)andlamenessSquealingwhenforcedtomovePostmortemfindings:VesiclesonmucousmembranesandskinAntemortemfindings:74Vesicularexanthema.Pigwalkingonkneesduetopainfromthevesicularlesiononthefeet.Vesicularexanthema.Pigwalki75FootandMouthDisease(FMD,Aphthousfever)FMDisacontagious,viraldiseaseofswine,cattle,sheep,goatsandpigsandotherclovenfootedanimals.Thediseaseinpigsismildandisimportantasbeingapotentialdangerfortransmissiontocattle.FootandMouthDisease(FMD,A76Antemortemfindings:Incubation3–15days.PigsthatarefedfoodwastescontaminatedwithFMDVmayshowsignsofinfectionin1–3days.Snout(Fig.116)andtonguelesionsverymoninpigsDullnessandlackofappetiteSalivationanddroolingDetachmentoftheskinonapig'sfoot(Fig.)ShakingoffeetandlamenessduetoleglesionsSomestrainsofFMDinswinedonotshowvesiclesbutshowerosions.Antemortemfindings:77FMD.Vesicleonthesnoutinapig.FMD.Vesicleonthesnoutina78FMDDetachmentofepitheliumonthepig'sfoot.FMDDetachmentofepitheliumo79AfricanSwineFever(ASF)ASFisahighlycontagiousviraldiseaseofdomesticpigsmanifestedbyfever,blotchingofskin,haemorrhageofthelymphnodes,internalorgansandhaemorrhageofthegastrointestinaltract.Itisobservedinacuteandoccasionallysubacuteandchronicforms.AfricanSwineFever(ASF)ASFi80Antemortemfindings:Incubation:3–15daysFever(upto42°C)Labouredbreathing,coughingNasalandoculardischargeLossofappetiteanddiarrhoeaVomitingIncoordinationCyanosisoftheextremitiesandhaemorrhagesofskinInchronicstage,emaciationandedematousswellingunderthemandibleandoverlegjointsRecumbencyAntemortemfindings:81Africanswinefever.Blotchyskin,cyanosisandhaemorrhage.Africanswinefever.Blotchys82巴氏桿菌病豬呼吸道疾病常伴有不產(chǎn)毒巴氏桿菌的感染。這種細(xì)菌本身可導(dǎo)致肺炎，但多數(shù)情況下是作為二次感染繼發(fā)于地方性肺炎（EP）或繁殖呼吸綜合癥（PRRS）之后。易感10～18周齡生長(zhǎng)豬。巴氏桿菌病豬呼吸道疾病常伴有不產(chǎn)毒巴氏桿菌的感染。這種細(xì)菌本83癥狀母豬與仔豬

：少見(jiàn)。斷奶豬與生長(zhǎng)豬

急性發(fā)?。?/p>

嚴(yán)重的急性肺炎，影響全部肺組織。體溫升高。流鼻涕。死亡率升高。呼吸加快。皮膚變色，尤其是耳端皮膚（由毒素或心包感染引起）。癥狀母豬與仔豬：少見(jiàn)。84亞急性發(fā)?。悍窝纵^輕，但常伴有心包炎和胸膜炎?？人浴Ａ鞅翘?。瘦弱。死亡率升高。亞急性發(fā)?。?5Pasteurella

multocidaPasteurellamultocida86豬皮膚疾病的鑒別診斷課件87豬皮膚疾病的鑒別診斷課件88豬皮膚疾病的鑒別診斷課件89豬皮膚疾病的鑒別診斷課件90豬皮膚疾病的鑒別診斷課件91Infectedcatbite:

PasteurellaMultocida

PasteurellaMultocidainfectionsdevelopinapproximately80%ofthosebittenbycats.Therednessischaracterizedbyonsetwithin24hoursofthebite.AmoxicillinclavulanateorPenicillinVarethefirst-lineantibioticagents.Infectedcatbite:

Pasteurell92乳腺炎很多種細(xì)菌的原發(fā)感染都會(huì)引起乳房炎，其它疾病引起的繼發(fā)感染也可能導(dǎo)致乳房炎。通常在母豬當(dāng)中個(gè)別出現(xiàn)，有時(shí)也會(huì)大群發(fā)病。這種病分娩前后出現(xiàn)，大約12小時(shí)以后表現(xiàn)臨床癥狀。可能由初次侵入乳房的細(xì)菌感染所致，也有可能由長(zhǎng)期亞臨床感染加劇造成。細(xì)菌感染的途徑可能是通過(guò)乳頭上的小孔，也可能是通過(guò)血液，或被仔豬咬傷。斷奶時(shí)發(fā)病也較常見(jiàn)。

乳腺炎很多種細(xì)菌的原發(fā)感染都會(huì)引起乳房炎，其它疾病引起的繼發(fā)93能夠?qū)е氯榉垦椎募?xì)菌可分成三大類：大腸桿菌、葡萄球菌和鏈球菌，以及雜類細(xì)菌。大腸桿菌乳房炎：大腸桿菌是與埃希氏大腸桿菌關(guān)系密切的一組細(xì)菌，最常見(jiàn)的是埃希氏大腸桿菌和克氏桿菌。這種病原可造成嚴(yán)重的乳房炎，致使母豬呈現(xiàn)嚴(yán)重癥狀，泌乳下降，仔豬生長(zhǎng)緩慢。典型特征是乳房表面變色，乳房周圍皮膚及耳部、尾部皮膚呈深藍(lán)色。由于該病原在母豬的糞和尿當(dāng)中普遍存在，它可能引起整個(gè)豬群的問(wèn)題。這種病原在豬場(chǎng)當(dāng)中無(wú)所不在，應(yīng)該算是一種環(huán)境性病原。

能夠?qū)е氯榉垦椎募?xì)菌可分成三大類：大腸桿菌、葡萄球菌和鏈球菌94葡萄球菌和鏈球菌乳房炎－

這種病通常不如大腸桿菌乳房炎嚴(yán)重，并且僅影響個(gè)別母豬的個(gè)別乳腺，病豬通常不表現(xiàn)病癥。但嚴(yán)重的急性葡萄球菌感染會(huì)導(dǎo)致乳房腫脹、變硬，并向母豬血液中排放毒素。通常只有一個(gè)乳房會(huì)感染。與大腸桿菌不同，這種病原并非環(huán)境性病原，而是源自皮膚，甚至可能是母豬自己的乳頭泌乳孔。有證據(jù)顯示，這種病原可在豬體內(nèi)以亞臨床感染的形式存在，奶牛和羊身當(dāng)中也有類似情況。這種亞臨床感染在分娩時(shí)或分娩之后可轉(zhuǎn)為臨床發(fā)病。

葡萄球菌和鏈球菌乳房炎－95雜類細(xì)菌－除上述兩類以外的細(xì)菌。例如假單胞菌，其感染可引發(fā)嚴(yán)重的乳房炎和敗血病，且具有抗藥性。幸運(yùn)的是這種感染很少見(jiàn)。雜類細(xì)菌－96母豬

急性發(fā)?。?/p>

分娩時(shí)或分娩前出現(xiàn)食欲不振。明顯病態(tài)，不讓仔豬哺乳。體溫升高。眼瞼粘膜呈磚紅色?；疾∪榉砍始t色，腫脹，觸痛。整個(gè)乳房變色，但以患病乳房為主。慢性發(fā)?。ǔＲ?jiàn)于干奶母豬）：

乳房組織中有硬塊，但無(wú)觸痛?？赡軓睦锩鏉€到表面，成為潛在的傳染源，將疾病傳染給其它母豬。母豬急性發(fā)病：97PorcineDermatitisandNephropathySyndrome(PDNS)WithPDNSpigsremainalertwiththeabovedime-sized,raisedoftenrawskinlesionsmostabundantontherearlegsandbelly.Thekidneysofthesepigsareveryenlarged,oftenmorethanthreetofourtimesthenormalsize.Pigsmaydieorspontaneouslyrecover.PorcineDermatitisandNephrop98ClinicalsignsPDNSoccursmainlyingrowersandfinishers,12to14weeksofageandsporadicallyinotheragegroups.

Themoststrikingsigninliveclinicallyaffectedpigsistheappearanceofextensivepurplishredslightlyraisedblotchesofvarioussizesandshapesoverthechest,abdomen,thighsandforelegs.ClinicalsignsPDNSoccursmain99Overtimetheblotchesbeecoveredwithdarkcrustsandthenfadeleavingscars.

Thepigsaredepressedandmayhaveafever.Theyareusuallyreluctanttomoveeat,loseweight.Sometimestheybreathheavily.Mostpigswithskinlesionsdie.

Oedemaorfluidmaybeseenonthelimbsandaroundtheeyelids.

Superficiallymphnodesmaybeenlarged.

Diarrhoeainsomepigs.

Overtimetheblotchesbeecov100PDNSoccursmainlyingrowersandfinishers,12to14weeksofageandsporadicallyinotheragegroups.Themoststrikingsigninliveclinicallyaffectedpigsistheappearanceofextensivepurplishredslightlyraisedblotchesofvarioussizesandshapesoverthechest,abdomen,thighsandforelegs.Superficiallymphnodesmaybeenlarged.Diarrhoeainsomepigs.PDNSoccursmainlyingrowers101Overtimetheblotchesbeecoveredwithdarkcrustsandthenfadeleavingscars.Thepigsaredepressedandmayhaveafever.Theyareusuallyreluctanttomoveeat,loseweight.Sometimestheybreathheavily.Mostpigswithskinlesionsdie.Oedemaorfluidmaybeseenonthelimbsandaroundtheeyelids.Overtimetheblotchesbeecov102SkinlesionsassociatedwithPDNS

SkinlesionsassociatedwithP103豬皮膚疾病的鑒別診斷課件104豬皮膚疾病的鑒別診斷課件105LET’SHAVEAREST!LET’SHAVEAREST!106豬皮膚疾病的鑒別診斷課件107豬皮膚疾病的鑒別診斷豬皮膚疾病的鑒別診斷108表皮層真皮層基底層：主要為角質(zhì)化細(xì)胞棘層：為多邊形細(xì)胞粒層：為扁平細(xì)胞角質(zhì)層：為角質(zhì)化細(xì)胞乳頭層網(wǎng)層皮膚的結(jié)構(gòu)另：鼻還有透明層均由結(jié)締組織組成，分布有血管、神經(jīng)、淋巴管及相關(guān)的表皮附件表皮層真皮層基底層：主要為角質(zhì)化細(xì)胞棘層：為多邊形細(xì)109皮膚的功能維持體液、電解質(zhì)及大分子物質(zhì)的平衡防御化學(xué)因素、物理因素、微生物的損害或侵入感受觸覺(jué)、壓覺(jué)、痛覺(jué)、癢覺(jué)及溫度變化免疫調(diào)節(jié)維持體溫皮膚的功能維持體液、電解質(zhì)及大分子物質(zhì)的平衡防御化學(xué)因素、物110豬的皮膚病病因感染性非感染性細(xì)菌性病毒性真菌性寄生蟲(chóng)性環(huán)境性營(yíng)養(yǎng)性遺傳性腫瘤性雜病豬的皮膚病病因感染性非感染性細(xì)菌性病毒性真菌性寄生蟲(chóng)性環(huán)境性111細(xì)菌性：滲出性皮炎、鏈球菌病、耳壞死、螺旋體病、面部壞死、膿腫、丹毒、巴氏桿菌病、乳腺炎、水腫病、炭疽、惡性水腫病毒性：豬痘、豬水皰病、水皰性口炎、水皰疹、豬細(xì)小病毒病、自發(fā)性水皰病、豬瘟、非洲豬瘟真菌性：小孢子菌病、毛癬菌病、皮膚念珠菌病寄生蟲(chóng)性；疥螨病、蠕螨病、虱、蚤、蚊、蠅細(xì)菌性：滲出性皮炎、鏈球菌病、耳壞死、螺旋體病、面部壞死、膿112環(huán)境性：曬斑、光敏反應(yīng)、皮膚壞死、黏液囊炎、硬皮病、跛行及腳病變營(yíng)養(yǎng)性：角化不全、脂肪酸缺乏、碘缺乏、核黃素缺乏、泛酸缺乏、生物素缺乏、VA、VC、VE缺乏遺傳性：玫瑰糠疹、增生性皮炎、上皮增殖不全腫瘤性：黑素瘤、橫紋肌瘤、淋巴管瘤、乳頭狀瘤、纖維瘤、血管瘤、汗腺腺瘤、息肉雜?。浩ぱ啄I病綜合征環(huán)境性：曬斑、光敏反應(yīng)、皮膚壞死、黏液囊炎、硬皮病、跛行及腳113皮膚病的鑒別診斷頭頸步斑點(diǎn)、水泡、膿庖，脂溢性滲出物（皮脂溢），哺乳仔豬和斷奶仔豬，尤其眼周圍滲出性皮炎膿皰痂，糜爛，結(jié)痂，膿腫鏈球菌病斑塊，膿皰，結(jié)痂，脫毛，伴有瘙癢疥螨病膿皰，糜爛，壞死，哺乳仔豬眼下，頰部，唇結(jié)痂面部壞死眼周圍，結(jié)膜，額部水腫，多見(jiàn)于斷奶仔豬和青年育肥豬水腫病頭、咽部水腫惡性水腫鼻、面部及頸部變?yōu)榧t色至紫紅色敗血癥皮膚病的鑒別診斷頭頸步斑點(diǎn)、水泡、膿庖，脂溢性滲出物（皮脂溢114頭頸步母豬皮膚散在潰瘍、下頜骨處結(jié)痂褥瘡鼻、唇、口、舌部有水泡，膿皰，壞死口蹄疫、豬水皰病、水皰疹，水泡性口炎，細(xì)小病毒病，自發(fā)性水泡病水泡，潰爛，黑痂豬痘頭頸步母豬皮膚散在潰瘍、下頜骨處結(jié)痂褥瘡鼻、唇、口、舌部有水115耳部仔豬耳尖和耳廓后緣黑色壞死，潰瘍耳壞死，沙門(mén)氏菌病，丹毒育肥豬耳廓基部深度潰瘍，常為雙側(cè)性潰瘍性螺旋體病，敗血癥，豬瘟，非洲豬瘟，曬斑斑塊，內(nèi)耳有棕色或灰色痂膜，耳震顫，瘙癢，成年豬可見(jiàn)灰色厚痂疥螨病斑點(diǎn)，膿皰，黑痂滲出性皮炎，鏈球菌病圓形斑點(diǎn)，小鱗屑，耳后和頸部變?yōu)榉凵良t色癬菌?。ㄐ℃咦泳。┒孔胸i耳尖和耳廓后緣黑色壞死，潰瘍耳壞死，沙門(mén)氏菌病，丹毒116背部角化癥，脊柱兩側(cè)有干鱗屑，部分脫毛必需脂肪酸、VA、VC、VE、鋅等缺乏新生仔豬無(wú)上皮（表觀紅色、光亮、面積大）疥螨病、上皮增殖不全母豬最后肋骨的脊柱上部、腰部膿腫，壓迫性壞死褥袍，因產(chǎn)房?jī)?nèi)分娩時(shí)壓迫豬欄的板條或尖頭處背部角化癥，脊柱兩側(cè)有干鱗屑，部分脫毛必需脂肪酸、VA、VC117肩部母豬肩胛骨處皮膚呈大面積深度散在潰瘍，壞死，結(jié)痂多見(jiàn)于體況差褥瘡，因在太硬或鋼筋網(wǎng)結(jié)構(gòu)地面分娩，攝入能量太少肩部母豬肩胛骨處皮膚呈大面積深度散在潰瘍，壞死，結(jié)痂多見(jiàn)于體118腹部紅斑，膿皰，深棕色痂片，滲出滲出性皮炎，鏈球菌病，疥螨病，念珠菌病，生物素缺乏紅斑，圓形，鉆石樣紅色斑塊，常伴有中央壞死，發(fā)熱，厭食，關(guān)節(jié)炎丹毒繩索勒傷樣丘疹，蜀黍紅疹項(xiàng)圈，鱗片及鱗屑（3-14周齡豬）玫瑰糠疹粉色至圓形斑點(diǎn)，外周有鱗屑或痂片癬菌?。ㄐ℃咦泳?，毛癬菌?。└共考t斑，膿皰，深棕色痂片，滲出滲出性皮炎，鏈球菌病，疥螨病119腹部丘疹、厚痂、有裂紋，滲出物鋅缺乏（角化不全），增生性皮炎，滲出性皮炎水泡，膿皰，黑痂，病變部位中央凹陷，周圍呈圓形隆起豬痘，急性乳房炎泌乳母豬病變處有紅斑，尤其是仔豬胸部乳頭，后乳頭有紅色或黑色斑塊（痂）產(chǎn)房衛(wèi)生差，地面粗糙所致的外傷和感染腹部丘疹、厚痂、有裂紋，滲出物鋅缺乏（角化不全），增生性皮炎120后腹部及肋腹部紅斑，圓形或鉆石樣紅色斑塊，伴有中央壞死、發(fā)熱、厭食、關(guān)節(jié)炎丹毒丘疹，水泡，膿皰，鱗屑，結(jié)痂，皮脂溢滲出性皮炎，鏈球菌病膿皰，鱗屑，皮膚嚴(yán)重卷曲，脫毛，結(jié)痂，伴有角化過(guò)度疥螨病，煙酸、泛酸、核黃素、VA缺乏肋腹部有紅斑、糜爛或潰瘍肋部咬傷丘疹、圓形樣斑塊，蜀黍紅疹項(xiàng)圈，鱗屑（3-14周齡）豬玫瑰糠疹大小不一的粉色至圓形斑點(diǎn)，外周有鱗片或結(jié)痂癬菌?。ㄐ℃咦泳?，毛癬菌?。┖蟾共考袄吒共考t斑，圓形或鉆石樣紅色斑塊，伴有中央壞死、發(fā)熱121后腹部陰囊，外陰和會(huì)陰部紅斑敗血癥、曬斑尾壞死，潰瘍，膿腫（育肥豬）咬尾髖骨處大面積散在潰瘍，壞死，結(jié)痂（成年豬）褥瘡紅斑，黑色壞死，多見(jiàn)于陰囊和外陰部皮炎/腎病綜合征圓形隆起的小疹塊，蕁麻疹樣反應(yīng)昆蟲(chóng)叮咬，蠅、蚊、虱后腹部陰囊，外陰和會(huì)陰部紅斑敗血癥、曬斑尾壞死，潰瘍，膿腫（122腿（肢）紅斑，皮膚變?yōu)榧t色至紫色，多見(jiàn)于后踝周圍敗血癥丘疹，繩索勒傷樣斑塊，蜀黍紅疹項(xiàng)圈，鱗片及鱗屑，股中部及腿部有鱗屑（3-14周齡豬）玫瑰糠疹丘疹，厚痂，有裂紋，乳頭狀瘤鋅缺乏（角化不全），滲出性皮炎新生仔豬無(wú)上皮（表觀紅色、光亮、面積大）上皮增殖不全關(guān)節(jié)（后踝、肘、球節(jié)、坐骨關(guān)節(jié)）處皮膚過(guò)度纖維化，有潰瘍硬皮病，黏液囊炎哺乳仔豬腕，特別是后踝處皮膚壞死產(chǎn)房地面太硬所致的外傷腿（肢）紅斑，皮膚變?yōu)榧t色至紫色，多見(jiàn)于后踝周圍敗血癥丘疹，123肢遠(yuǎn)端、冠狀帶、腳厚，干痂，裂紋深角化不全，增生性皮炎，滲出性皮炎，疥螨病冠狀帶及附指（趾）周圍有水泡，膿皰，糜爛，跛行口蹄疫、豬水皰病、水泡性口炎，水皰疹，細(xì)小病毒病，自發(fā)性水泡病膿腫，有滲出物，冠狀帶腫脹蹄感染引起的Bush腳蹄壁增厚，水平嵴及與冠狀帶平行增生性皮炎肢遠(yuǎn)端、冠狀帶、腳厚，干痂，裂紋深角化不全，增生性皮炎，滲出124滲出性皮炎(

ExudativeEpidermitisorGreasypigdisease)Exudativeepidermitisisageneralizeddermatitisthatoccursin5-to60-day-oldpigsandischaracterizedbysuddenonset,withmorbidityof10-90%andmortalityof5-90%.Theacuteformusuallyaffectssucklingpiglets,whereasachronicformismoremonlyseeninweanerpigs.Ithasbeenreportedfrommostswine-producingareasoftheworld.

滲出性皮炎(ExudativeEpidermitiso125豬皮膚疾病的鑒別診斷課件126滲出性皮炎滲出性皮炎127Thegeneralisedform.

Thegeneralisedform.128Alocalisedlesionofgreasypigdisease.Thismaybecannibalised.Alocalisedlesionofgreasyp129EXUDATIVEEPIDERMITISSubacuteexudativeepidermitisaffectingtheface,limbsandventralabdomentinsucklingpiglets.

EXUDATIVEEPIDERMITIS130

EXUDATIVEEPIDERMITISExudativeepidermitis.Thisyoungpigshowsthecharacteristic?greasy?lesionontheventralabdomen.

131

EXUDATIVEEPIDERMITISChronicexudativeepidermitisovertheentirebodyinweanerpigapproximately5weeksold.

132鏈球菌病PigsKissing鏈球菌病PigsKissing133鏈球菌病豬鏈球菌病是一種人畜共患的急性、熱性傳染病，由C、D、E及L群鏈球菌引起的豬的多種疾病的總稱。表現(xiàn)為急性出血性敗血癥、心內(nèi)膜炎、腦膜炎、關(guān)節(jié)炎、哺乳仔豬下痢和孕豬流產(chǎn)等。

豬鏈球菌感染不僅可致豬敗血癥肺炎、腦膜炎、關(guān)節(jié)炎及心內(nèi)膜炎，而且可感染特定人群發(fā)病，并可致死亡，危害嚴(yán)重。

豬鏈球菌病可以通過(guò)傷口、消化道等途徑傳染給人，這種病原體早已長(zhǎng)期存在豬群身上，因?yàn)橥饨绛h(huán)境發(fā)生的變化使得病原體發(fā)生變異，從而突破種群障礙，開(kāi)始從豬傳播給人。鏈球菌病豬鏈球菌病是一種人畜共患的急性、熱性傳染病，由C、D134豬皮膚疾病的鑒別診斷課件135豬皮膚疾病的鑒別診斷課件136豬皮膚疾病的鑒別診斷課件137螺旋體病leptospirosisLeptospirosisisadiseaseofdomesticanimalscausedbybacteriabelongingtothegenusLeptospira.Theseorganismshaveaworldwidedistributionandcauseeconomiclossprimarilythroughreproductivewastage.Lossesaregreatestinanimalpopulationskeptundertheintensivefarmingsystemsfoundinthedevelopedworld.Specificstrainsaremaintainedbydifferentdomesticanimalhosts,e.g.serovarhardjoismaintainedbycattleandserovarbratislavaismaintainedbypigs.Leptospirosisisazoonosiswhichprimarilyaffectspeopleworkinginagricultureandrelatedoccupations.螺旋體病leptospirosisLeptospirosis138豬皮膚疾病的鑒別診斷課件139

140豬皮膚疾病的鑒別診斷課件141豬皮膚疾病的鑒別診斷課件142豬皮膚疾病的鑒別診斷課件143

144丹毒Swineerysipelasisaninfectioncharacterizedbydiamondshapedskinlesionsandinthechronicform,byvegetativeendocarditisandarthritis.ItiscausedbyErysipelothrixrhusiopathiae.丹毒Swineerysipelasisaninfec145ErysipelothrixrhusiopathiaeErysipelothrixrhusiopathiae146Erysipelothrixrhusiopathiae,Gram'sstain,highpower.Vegetativeendocarditislesion,showingthegram-positivefilamentstypicalofthisorganism.Erysipelothrixrhusiopathiae,147Columbiaagar,48h,aerobně.

Columbiaagar,48h,aerobně.148Antemortemfindings:HighmorbidityFeverinacutestagesConjunctivitisandvomitinginsomecasesBrightandalert,squealinginpainonmovementPigislethargicandstopseatingRaisedredandedematousrhomboidwheals(acuteandchronicforms)SloughingofskinintheareaoftherhomboidlesionSwollenjointsandlameness(chronicstage)SuddendeathinexcitedanimalsAntemortemfindings:149豬皮膚疾病的鑒別診斷課件150急性型Acutetype(麻疹型):全身皮膚に形成された菱形丘疹

急性型Acutetype(麻疹型):全身皮膚に形成さ151臀部皮膚に形成された隆起した淡紅色の菱形皮疹臀部皮膚に形成された隆起した淡紅色の菱形皮疹152SWINEERYSIPELASAcutesevereskinformofswineerysipelaswithextensivesmallraisedpink/redlesionssomedevelopingdarkscabs.SWINEERYSIPELAS153Acuteswineerysipelas,notethetypicalraisedpinklesionswithdiamondshapeddarkred/blackcentralareas.Acuteswineerysipelas,notet154Erysipelasskinlesions,close-up.Erysipelasskinlesions,close155Swineerysipelas.Diamondshapedskinlesions.Swineerysipelas.Diamondshap156慢性型Chronictype(関節(jié)炎型):関節(jié)炎のため起立困難を呈する豚

慢性型Chronictype(関節(jié)炎型):関節(jié)炎のため157ErysipelasrhomboidlesionsonadolphinskinErysipelasrhomboidlesionson158

Erysipelasistransmittedbydirectcontactwithinfectedanimalsortheirexcreta.Thephotoshowsthehandofaninfectedhandler.Erysipelasistransmittedby159ResolvingcellulitiscausedbyErysipelothrixrhusiopathiaefollowingtreatmentwithdoxycyclineandciprofloxacin.Resolvingcellulitiscausedby160VesicularstomatitisViraldiseaseofswine,cattle,horsesandoccasionallyman.ThediseaseiscausedbytwoantigenicallydistincttypesofvirusnamelyIndianaandNewJerseytypes.Vesicularstomatitisinswineismostmonlymanifestedbysnoutandfootlesions.VesicularstomatitisViraldise161Antemortemfindings:Incubation2–4daysFeverLesiononthetongue(Fig.)andsnoutLesionintheinterdigitalspaceorcoronarybandRefusaloffoodbutacceptanceofwaterWeightlossLamenessandexungulationAntemortemfindings:162"Vesicularstomatitisvirus,purifiedfromaninfectedcellculture.Thisisanimportantpathogenicvirusofcattle,causingfeverandvesiclesinthemouthandonthefeet.Negativelystainedvirions:notethattheyareclearly"bulletshaped"justlikerabiesvirus.Magnificationapproximatelyx40,000.""Vesicularstomatitisvirus,p163Vesicularstomatitis.Detachmentofepitheliumofthepigtongue.Vesicularstomatitis.Detachme164Blanchedareasonthehardpalate,dentalpadandgums.Blanchedareasonthehardpal165Swinevesiculardisease(SWD)Acontagiousviraldiseaseofswineclinicallyindistinguishablefromvesicularstomatitis,footandmouthdiseaseandvesicularexanthemaofswine.Antemortemfindings:Incubation2–4daysFever40–41°CSnout(Fig),oralandfeetvesicularlesionsLamenessSwinevesiculardisease(SWD)A166Earlylesionsoncoronarybandoffoot.Earlylesionsoncoronaryband167Oldlesionsonfootwithpartialseparationofhoof.Oldlesionsonfootwithparti168Oldlesionsonrecoveredpigshowingbandinggrowingoutofhoof.Oldlesionsonrecoveredpigs169Swinevesiculardisease.Snoutvesicularlesion.Swinevesiculardisease.Snout170Vesicularlesionsonsnout.Vesicularlesionsonsnout.171Recentlyrupturedblisteronrimofsnout.Recentlyrupturedblisteronr172Recentlyrupturedblisteronfoot.Recentlyrupturedblisteronf173Separationofhornfollowingruptureofblister.Separationofhornfollowingr174Rupturedvesicleonsnoutandtongue.Rupturedvesicleonsnoutand175Lesionsoncoronaryband,bulbofheelandsupernumerarydigit.Lesionsoncoronaryband,bulb176Recentlyrupturedvesicleoninterdigitalspace.Recentlyrupturedvesicleoni177Rupturedvesiclesoncoronaryband.Separationofbands.Rupturedvesiclesoncoronary178Vesicularexanthemaofswine(VES)Anacute,contagious,viraldiseaseofswinemanifestedbytheformationofvesicles.VesicularexanthemaisindistinguishablefromtheotherswinediseasessuchasFMD,VSandSVD.Vesicularexanthemaofswine(179Antemortemfindings:Incubation:2–4daysLargenumberofhogsareaffected.HeavymortalityinsucklingpigsBlotchyrashinunpigmentedskin(exanthema)Vesiclesonthesnoutandinthemouth.Rupturedvesiclesresult