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天然生物醫(yī)用高分子材料的研究進(jìn)展一、本文概述Overviewofthisarticle隨著科學(xué)技術(shù)的快速發(fā)展,生物醫(yī)用高分子材料作為一種重要的生物材料,其在醫(yī)療領(lǐng)域的應(yīng)用越來(lái)越廣泛。這些材料以其獨(dú)特的生物相容性、可降解性和良好的機(jī)械性能等特點(diǎn),被廣泛應(yīng)用于藥物載體、組織工程、生物傳感器、醫(yī)療器械等多個(gè)方面。本文旨在全面綜述天然生物醫(yī)用高分子材料的研究進(jìn)展,包括其來(lái)源、性質(zhì)、制備方法、應(yīng)用領(lǐng)域以及面臨的挑戰(zhàn)和未來(lái)的發(fā)展趨勢(shì)。Withtherapiddevelopmentofscienceandtechnology,biomedicalpolymermaterials,asanimportanttypeofbiomaterial,areincreasinglywidelyusedinthemedicalfield.Thesematerialsarewidelyusedindrugcarriers,tissueengineering,biosensors,medicaldevices,andotherfieldsduetotheiruniquebiocompatibility,biodegradability,andgoodmechanicalproperties.Thisarticleaimstocomprehensivelyreviewtheresearchprogressofnaturalbiomedicalpolymermaterials,includingtheirsources,properties,preparationmethods,applicationfields,challengesandfuturedevelopmenttrends.我們將首先介紹天然生物醫(yī)用高分子材料的來(lái)源和分類,包括天然多糖、天然蛋白質(zhì)、天然橡膠等。然后,我們將重點(diǎn)討論這些材料的制備方法和改性技術(shù),以提高其性能并滿足特定的應(yīng)用需求。我們還將詳細(xì)介紹這些材料在藥物遞送、組織工程、生物成像和診斷等領(lǐng)域的應(yīng)用實(shí)例,以展示其巨大的應(yīng)用潛力。Wewillfirstintroducethesourcesandclassificationsofnaturalbiomedicalpolymermaterials,includingnaturalpolysaccharides,naturalproteins,naturalrubber,etc.Then,wewillfocusondiscussingthepreparationmethodsandmodificationtechniquesofthesematerialstoimprovetheirperformanceandmeetspecificapplicationrequirements.Wewillalsoprovideadetailedintroductiontotheapplicationexamplesofthesematerialsinfieldssuchasdrugdelivery,tissueengineering,biologicalimaging,anddiagnosis,todemonstratetheirenormouspotentialforapplication.在綜述的過(guò)程中,我們將關(guān)注天然生物醫(yī)用高分子材料的研究熱點(diǎn)和前沿技術(shù),如納米技術(shù)、生物活性分子的引入、復(fù)合材料的制備等。我們也將探討這些材料在實(shí)際應(yīng)用中面臨的挑戰(zhàn),如生物相容性、機(jī)械性能、穩(wěn)定性等問(wèn)題,并提出可能的解決方案。Inthereviewprocess,wewillfocusontheresearchhotspotsandcutting-edgetechnologiesofnaturalbiomedicalpolymermaterials,suchasnanotechnology,theintroductionofbioactivemolecules,andthepreparationofcompositematerials.Wewillalsoexplorethechallengesthesematerialsfaceinpracticalapplications,suchasbiocompatibility,mechanicalproperties,stability,etc.,andproposepossiblesolutions.我們將展望天然生物醫(yī)用高分子材料的未來(lái)發(fā)展趨勢(shì),包括新材料的開發(fā)、新技術(shù)的應(yīng)用以及跨學(xué)科的研究合作等。我們相信,隨著科學(xué)技術(shù)的不斷進(jìn)步,天然生物醫(yī)用高分子材料將在醫(yī)療領(lǐng)域發(fā)揮更加重要的作用,為人類的健康和生活質(zhì)量做出更大的貢獻(xiàn)。Wewilllookforwardtothefuturedevelopmenttrendsofnaturalbiomedicalpolymermaterials,includingthedevelopmentofnewmaterials,theapplicationofnewtechnologies,andinterdisciplinaryresearchcooperation.Webelievethatwiththecontinuousprogressofscienceandtechnology,naturalbiomedicalpolymermaterialswillplayamoreimportantroleinthemedicalfield,makinggreatercontributionstohumanhealthandqualityoflife.二、天然生物醫(yī)用高分子材料的來(lái)源與特性TheSourcesandCharacteristicsofNaturalBiomedicalPolymerMaterials天然生物醫(yī)用高分子材料主要來(lái)源于生物體自身或者通過(guò)生物過(guò)程產(chǎn)生的天然高分子化合物。這些材料因其良好的生物相容性、可降解性和獨(dú)特的物理化學(xué)特性,在生物醫(yī)用領(lǐng)域具有廣泛的應(yīng)用前景。Naturalbiomedicalpolymermaterialsmainlycomefromorganismsthemselvesornaturalpolymercompoundsproducedthroughbiologicalprocesses.Thesematerialshavebroadapplicationprospectsinthebiomedicalfieldduetotheirgoodbiocompatibility,biodegradability,anduniquephysicochemicalproperties.天然生物醫(yī)用高分子材料的來(lái)源主要包括天然植物、動(dòng)物和微生物。植物來(lái)源的高分子材料如纖維素、淀粉、木質(zhì)素等,具有良好的生物降解性和生物相容性。動(dòng)物來(lái)源的高分子材料如膠原蛋白、殼聚糖、透明質(zhì)酸等,具有良好的生物活性和機(jī)械性能。微生物來(lái)源的高分子材料如聚乳酸、聚羥基脂肪酸酯等,具有良好的生物降解性和環(huán)境友好性。Themainsourcesofnaturalbiomedicalpolymermaterialsincludenaturalplants,animals,andmicroorganisms.Plantderivedpolymermaterialssuchascellulose,starch,lignin,etc.havegoodbiodegradabilityandbiocompatibility.Polymermaterialsfromanimalsourcessuchascollagen,chitosan,hyaluronicacid,etc.havegoodbiologicalactivityandmechanicalproperties.Polymermaterialsderivedfrommicroorganisms,suchaspolylacticacidandpolyhydroxyfattyacidesters,havegoodbiodegradabilityandenvironmentalfriendliness.天然生物醫(yī)用高分子材料具有許多獨(dú)特的特性,使其成為生物醫(yī)用領(lǐng)域的理想選擇。這些材料具有良好的生物相容性,能夠與生物組織無(wú)縫結(jié)合,減少排斥反應(yīng)和炎癥反應(yīng)。許多天然生物醫(yī)用高分子材料具有可降解性,能夠在體內(nèi)被自然降解,避免長(zhǎng)期植入引起的并發(fā)癥。這些材料還具有良好的物理和化學(xué)性能,如機(jī)械強(qiáng)度、穩(wěn)定性、吸水性等,能夠滿足不同生物醫(yī)用領(lǐng)域的需求。Naturalbiomedicalpolymermaterialshavemanyuniquecharacteristics,makingthemanidealchoiceinthebiomedicalfield.Thesematerialshavegoodbiocompatibilityandcanseamlesslybindwithbiologicaltissues,reducingrejectionandinflammatoryreactions.Manynaturalbiomedicalpolymermaterialshavedegradabilityandcanbenaturallydegradedinthebody,avoidingcomplicationscausedbylong-termimplantation.Thesematerialsalsohavegoodphysicalandchemicalproperties,suchasmechanicalstrength,stability,waterabsorption,etc.,whichcanmeettheneedsofdifferentbiomedicalfields.然而,天然生物醫(yī)用高分子材料也存在一些挑戰(zhàn)和限制。例如,其來(lái)源可能受到地域、季節(jié)和生物多樣性的限制,導(dǎo)致供應(yīng)不穩(wěn)定。天然高分子材料的結(jié)構(gòu)和性能可能受到多種因素的影響,如生長(zhǎng)條件、提取方法和處理過(guò)程等。因此,在研究和應(yīng)用天然生物醫(yī)用高分子材料時(shí),需要綜合考慮其來(lái)源、特性以及潛在的應(yīng)用領(lǐng)域,以實(shí)現(xiàn)最佳的效果和效益。However,naturalbiomedicalpolymermaterialsalsofacesomechallengesandlimitations.Forexample,itssourcemaybelimitedbygeography,season,andbiodiversity,leadingtounstablesupply.Thestructureandpropertiesofnaturalpolymermaterialsmaybeinfluencedbyvariousfactors,suchasgrowthconditions,extractionmethods,andprocessingprocesses.Therefore,whenresearchingandapplyingnaturalbiomedicalpolymermaterials,itisnecessarytocomprehensivelyconsidertheirsources,characteristics,andpotentialapplicationareasinordertoachievethebestresultsandbenefits.三、天然生物醫(yī)用高分子材料在醫(yī)學(xué)領(lǐng)域的應(yīng)用Theapplicationofnaturalbiomedicalpolymermaterialsinthemedicalfield天然生物醫(yī)用高分子材料以其獨(dú)特的生物相容性、生物活性及可降解性,在醫(yī)學(xué)領(lǐng)域的應(yīng)用日益廣泛。這些材料不僅可用于藥物傳遞系統(tǒng),還可用于組織工程和再生醫(yī)學(xué)等領(lǐng)域,為現(xiàn)代醫(yī)學(xué)提供了豐富的工具和可能性。Naturalbiomedicalpolymermaterialsareincreasinglywidelyusedinthemedicalfieldduetotheiruniquebiocompatibility,biologicalactivity,andbiodegradability.Thesematerialscannotonlybeusedindrugdeliverysystems,butalsoinfieldssuchastissueengineeringandregenerativemedicine,providingrichtoolsandpossibilitiesformodernmedicine.在藥物傳遞系統(tǒng)方面,天然生物醫(yī)用高分子材料可以作為藥物載體,通過(guò)控制藥物的釋放速率和靶向性,實(shí)現(xiàn)藥物的精準(zhǔn)治療。例如,殼聚糖和透明質(zhì)酸等天然高分子材料已被廣泛用于制備藥物緩釋系統(tǒng)和靶向藥物傳遞系統(tǒng),顯示出良好的應(yīng)用前景。Intermsofdrugdeliverysystems,naturalbiomedicalpolymermaterialscanserveasdrugcarriers,achievingprecisedrugtreatmentbycontrollingdrugreleaserateandtargeting.Forexample,naturalpolymermaterialssuchaschitosanandhyaluronicacidhavebeenwidelyusedinthepreparationofdrugsustained-releasesystemsandtargeteddrugdeliverysystems,demonstratinggoodapplicationprospects.在組織工程和再生醫(yī)學(xué)方面,天然生物醫(yī)用高分子材料可以作為支架材料,為細(xì)胞的生長(zhǎng)和分化提供適宜的環(huán)境。這些材料具有良好的生物相容性和生物活性,可以促進(jìn)細(xì)胞的粘附和增殖,進(jìn)而實(shí)現(xiàn)組織的再生和修復(fù)。例如,膠原蛋白和纖維蛋白等天然高分子材料已被廣泛用于制備皮膚、骨骼和血管等組織工程產(chǎn)品。Intissueengineeringandregenerativemedicine,naturalbiomedicalpolymermaterialscanserveasscaffoldmaterials,providingasuitableenvironmentforcellgrowthanddifferentiation.Thesematerialshavegoodbiocompatibilityandbiologicalactivity,whichcanpromotecelladhesionandproliferation,therebyachievingtissueregenerationandrepair.Forexample,naturalpolymermaterialssuchascollagenandfibrinhavebeenwidelyusedinthepreparationoftissueengineeringproductssuchasskin,bones,andbloodvessels.天然生物醫(yī)用高分子材料還在醫(yī)療器械、生物成像和診斷等方面發(fā)揮著重要作用。例如,明膠和瓊脂糖等天然高分子材料可用于制備生物相容性良好的醫(yī)療器械,如導(dǎo)管、縫合線和人工器官等。某些天然高分子材料還具有特殊的生物熒光性質(zhì),可用于生物成像和診斷。Naturalbiomedicalpolymermaterialsalsoplayanimportantroleinmedicaldevices,biologicalimaging,anddiagnosis.Forexample,naturalpolymermaterialssuchasgelatinandagarosecanbeusedtopreparebiocompatiblemedicaldevices,suchascatheters,sutures,andartificialorgans.Somenaturalpolymermaterialsalsohavespecialbiologicalfluorescenceproperties,whichcanbeusedforbiologicalimaginganddiagnosis.天然生物醫(yī)用高分子材料在醫(yī)學(xué)領(lǐng)域的應(yīng)用具有廣闊的前景和巨大的潛力。隨著科學(xué)技術(shù)的不斷進(jìn)步和研究的深入,這些材料有望在醫(yī)學(xué)領(lǐng)域發(fā)揮更大的作用,為人類的健康事業(yè)做出更大的貢獻(xiàn)。Theapplicationofnaturalbiomedicalpolymermaterialsinthemedicalfieldhasbroadprospectsandenormouspotential.Withthecontinuousprogressofscienceandtechnologyandthedeepeningofresearch,thesematerialsareexpectedtoplayagreaterroleinthemedicalfieldandmakegreatercontributionstohumanhealth.四、天然生物醫(yī)用高分子材料的研究進(jìn)展Researchprogressinnaturalbiomedicalpolymermaterials近年來(lái),天然生物醫(yī)用高分子材料在醫(yī)學(xué)領(lǐng)域的應(yīng)用引起了廣泛關(guān)注,這些材料因其獨(dú)特的生物相容性、可降解性和生物活性等特性,成為了生物醫(yī)學(xué)工程領(lǐng)域的研究熱點(diǎn)。隨著科技的不斷進(jìn)步,天然生物醫(yī)用高分子材料的研究也取得了顯著進(jìn)展。Inrecentyears,theapplicationofnaturalbiomedicalpolymermaterialsinthemedicalfieldhasattractedwidespreadattention.Thesematerialshavebecomearesearchhotspotinthefieldofbiomedicalengineeringduetotheiruniquecharacteristicssuchasbiocompatibility,biodegradability,andbiologicalactivity.Withthecontinuousprogressoftechnology,significantprogresshasbeenmadeintheresearchofnaturalbiomedicalpolymermaterials.在生物相容性方面,天然生物醫(yī)用高分子材料能夠與生物組織良好地相容,減少異物反應(yīng)和免疫排斥。例如,殼聚糖作為一種天然多糖,具有良好的生物相容性和生物可降解性,已被廣泛應(yīng)用于藥物載體、組織工程和傷口敷料等領(lǐng)域。膠原蛋白、透明質(zhì)酸等天然高分子材料也在生物相容性方面表現(xiàn)出色,被廣泛用于醫(yī)學(xué)美容、眼科手術(shù)和骨科修復(fù)等領(lǐng)域。Intermsofbiocompatibility,naturalbiomedicalpolymermaterialscanbewellcompatiblewithbiologicaltissues,reducingforeignbodyreactionsandimmunerejection.Forexample,chitosan,asanaturalpolysaccharidewithgoodbiocompatibilityandbiodegradability,hasbeenwidelyusedinfieldssuchasdrugcarriers,tissueengineering,andwounddressings.Naturalpolymermaterialssuchascollagenandhyaluronicacidalsoexhibitexcellentbiocompatibilityandarewidelyusedinfieldssuchasmedicalbeauty,ophthalmicsurgery,andorthopedicrepair.在可降解性方面,天然生物醫(yī)用高分子材料能夠在體內(nèi)或體外環(huán)境中逐漸降解,避免了長(zhǎng)期植入物對(duì)生物體的潛在危害。例如,聚乳酸(PLA)和聚己內(nèi)酯(PCL)等天然高分子材料具有良好的可降解性,已被廣泛應(yīng)用于藥物控釋系統(tǒng)、組織工程和植入物等領(lǐng)域。這些材料可以在體內(nèi)分解為無(wú)毒的小分子,通過(guò)代謝排出體外,對(duì)生物體無(wú)長(zhǎng)期不良影響。Intermsofbiodegradability,naturalbiomedicalpolymermaterialscangraduallydegradeinvivoorinvitroenvironments,avoidingthepotentialharmoflong-termimplantstotheorganism.Forexample,naturalpolymermaterialssuchaspolylacticacid(PLA)andpolycaprolactone(PCL)havegoodbiodegradabilityandhavebeenwidelyusedinfieldssuchasdrugcontrolledreleasesystems,tissueengineering,andimplants.Thesematerialscanbebrokendownintonon-toxicsmallmoleculesinthebodyandexcretedthroughmetabolism,withnolong-termadverseeffectsontheorganism.在生物活性方面,天然生物醫(yī)用高分子材料能夠與生物組織發(fā)生相互作用,促進(jìn)細(xì)胞的生長(zhǎng)、分化和代謝。例如,絲素蛋白作為一種天然高分子材料,具有良好的生物活性,能夠促進(jìn)細(xì)胞粘附、增殖和分化,已被廣泛應(yīng)用于組織工程和生物傳感器等領(lǐng)域。一些天然高分子材料還具有抗菌、抗炎和抗腫瘤等生物活性,為醫(yī)學(xué)治療提供了新的思路和方法。Intermsofbiologicalactivity,naturalbiomedicalpolymermaterialscaninteractwithbiologicaltissues,promotingcellgrowth,differentiation,andmetabolism.Forexample,silkfibroin,asanaturalpolymermaterial,hasgoodbiologicalactivityandcanpromotecelladhesion,proliferation,anddifferentiation.Ithasbeenwidelyusedinfieldssuchastissueengineeringandbiosensors.Somenaturalpolymermaterialsalsohavebiologicalactivitiessuchasantibacterial,anti-inflammatory,andanti-tumor,providingnewideasandmethodsformedicaltreatment.天然生物醫(yī)用高分子材料的研究進(jìn)展為醫(yī)學(xué)領(lǐng)域的發(fā)展帶來(lái)了新的機(jī)遇和挑戰(zhàn)。未來(lái),隨著科技的不斷進(jìn)步和創(chuàng)新,相信天然生物醫(yī)用高分子材料將在醫(yī)學(xué)領(lǐng)域發(fā)揮更加重要的作用,為人類的健康和福祉做出更大的貢獻(xiàn)。Theresearchprogressofnaturalbiomedicalpolymermaterialshasbroughtnewopportunitiesandchallengestothedevelopmentofthemedicalfield.Inthefuture,withthecontinuousprogressandinnovationoftechnology,itisbelievedthatnaturalbiomedicalpolymermaterialswillplayamoreimportantroleinthemedicalfield,makinggreatercontributionstohumanhealthandwell-being.五、天然生物醫(yī)用高分子材料的挑戰(zhàn)與展望ChallengesandProspectsofNaturalBiomedicalPolymerMaterials盡管天然生物醫(yī)用高分子材料在醫(yī)療領(lǐng)域已取得了顯著的進(jìn)展,但仍面臨一些挑戰(zhàn)和問(wèn)題需要解決。天然高分子材料的來(lái)源和提取過(guò)程可能受到地域、季節(jié)和生態(tài)環(huán)境的影響,導(dǎo)致其供應(yīng)不穩(wěn)定和成本波動(dòng)。天然高分子材料的結(jié)構(gòu)和性能可能因來(lái)源不同而有所差異,這對(duì)其在醫(yī)療應(yīng)用中的穩(wěn)定性和可靠性提出了挑戰(zhàn)。Althoughnaturalbiomedicalpolymermaterialshavemadesignificantprogressinthemedicalfield,theystillfacesomechallengesandproblemsthatneedtobesolved.Thesourceandextractionprocessofnaturalpolymermaterialsmaybeinfluencedbygeography,season,andecologicalenvironment,leadingtounstablesupplyandcostfluctuations.Thestructureandpropertiesofnaturalpolymermaterialsmayvaryduetodifferentsources,whichposeschallengestotheirstabilityandreliabilityinmedicalapplications.為了克服這些挑戰(zhàn),研究者們正在探索新的提取和加工技術(shù),以提高天然高分子材料的產(chǎn)量和質(zhì)量。同時(shí),通過(guò)基因工程和生物技術(shù)的手段,有望培育出具有更優(yōu)異性能和穩(wěn)定性的新型天然高分子材料。將天然高分子材料與其他生物材料或納米材料進(jìn)行復(fù)合,以制備具有多功能和高性能的復(fù)合材料,也是當(dāng)前研究的熱點(diǎn)之一。Toovercomethesechallenges,researchersareexploringnewextractionandprocessingtechniquestoincreasetheyieldandqualityofnaturalpolymermaterials.Meanwhile,throughgeneticengineeringandbiotechnology,itisexpectedtocultivatenewnaturalpolymermaterialswithbetterperformanceandstability.Thecompositeofnaturalpolymermaterialswithotherbiomaterialsornanomaterialstopreparemultifunctionalandhigh-performancecompositematerialsisalsooneofthecurrentresearchhotspots.展望未來(lái),天然生物醫(yī)用高分子材料在醫(yī)療領(lǐng)域的應(yīng)用前景廣闊。隨著科技的不斷進(jìn)步和研究的深入,我們有理由相信,天然高分子材料將在藥物遞送、組織工程、再生醫(yī)學(xué)等領(lǐng)域發(fā)揮更大的作用。隨著環(huán)保意識(shí)的日益增強(qiáng),天然高分子材料作為一種可再生和生物降解的材料,將在醫(yī)療領(lǐng)域得到更廣泛的應(yīng)用。Lookingaheadtothefuture,naturalbiomedicalpolymermaterialshavebroadapplicationprospectsinthemedicalfield.Withthecontinuousprogressoftechnologyandthedeepeningofresearch,wehavereasontobelievethatnaturalpolymermaterialswillplayagreaterroleinfieldssuchasdrugdelivery,tissueengineering,andregenerativemedicine.Withtheincreasingawarenessofenvironmentalprotection,naturalpolymermaterials,asarenewableandbiodegradablematerial,willbewidelyusedinthemedicalfield.天然生物醫(yī)用高分子材料作為一種具有優(yōu)異生物相容性和生物活性的材料,在醫(yī)療領(lǐng)域具有巨大的應(yīng)用潛力。然而,要充分發(fā)揮其優(yōu)勢(shì)并克服現(xiàn)有挑戰(zhàn),需要研究者們不斷探索和創(chuàng)新,以推動(dòng)天然生物醫(yī)用高分子材料的持續(xù)發(fā)展。Naturalbiomedicalpolymermaterials,asatypeofmaterialwithexcellentbiocompatibilityandbiologicalactivity,haveenormouspotentialforapplicationinthemedicalfield.However,tofullyleverageitsadvantagesandovercomeexistingchallenges,researchersneedtoconstantlyexploreandinnovatetopromotethesustainabledevelopmentofnaturalbiomedicalpolymermaterials.六、結(jié)論Conclusion隨著科學(xué)技術(shù)的日益發(fā)展,天然生物醫(yī)用高分子材料因其獨(dú)特的生物相容性、可降解性、低毒性以及良好的功能特性,已成為生物醫(yī)用材料領(lǐng)域的研究熱點(diǎn)。本文綜述了近年來(lái)天然生物醫(yī)用高分子材料在制備技術(shù)、性能優(yōu)化以及臨床應(yīng)用等方面的研究進(jìn)展。Withtheincreasingdevelopmentofscienceandtechnology,naturalbiomedicalpolymermaterialshavebecomearesearchhotspotinthefieldofbiomedicalmaterialsduetotheiruniquebiocompatibility,biodegradability,lowtoxicity,andgoodfunctionalproperties.Thisarticlereviewstheresearchprogressofnaturalbiomedicalpolymermaterialsinpreparationtechnology,performanceoptimization,andclinicalapplicationsinrecentyears.在制備技術(shù)方面,研究者們通過(guò)物理、化學(xué)和生物等方法,不斷探索和優(yōu)化天然高分子材料的提取和加工技術(shù),提高了材料的純度和性能。同時(shí),通過(guò)分子設(shè)計(jì)、復(fù)合改性等技術(shù)手段,成功制備出一系列具有優(yōu)異性能的新型天然生物醫(yī)用高分子材料。Intermsofpreparationtechnology,researcherscontinuouslyexploreandoptimizetheextractionandprocessingtechniquesofnaturalpolymermaterialsthroughphysical,chemical,andbiologicalmethods,improvingthepurityandperformanceofthematerials.Atthesametime,aseriesofnovelnaturalbiomedicalpolymermaterialswithexcellentperformancehavebeensuccessfullypreparedthroughmoleculardesign,compositemodificationandothertechnicalmeans.在性能優(yōu)化方面,天然生物醫(yī)用高分子材料在生物相容性、力學(xué)性能、藥物載體性能等方面取得了顯著進(jìn)展。通過(guò)調(diào)控材料的結(jié)構(gòu)和組成,可以實(shí)現(xiàn)對(duì)材料性能的精準(zhǔn)調(diào)控,滿足不同醫(yī)用領(lǐng)域的需求。Intermsofperformanceoptimization,naturalbiomedicalpolymermaterialshavemadesignificantprogressinbiocompatibility,mechanicalproperties,anddrugcarrierperformance.Byregulatingthestructureandcompositionofmaterials,precisecontrolo
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