L-012-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEL-012Cat.No.:HY-118315CASNo.:143323-55-1分?式:C??H?ClN?O?分?量:288.69作?靶點:Others;ReactiveOxygenSpecies作?通路:Others;Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性L-012?種化學(xué)發(fā)光探針，與?體?液、?腔和??腹腔中活化的中性粒細(xì)胞產(chǎn)?的各種類型的ROS發(fā)?反應(yīng)，并產(chǎn)?強烈的化學(xué)發(fā)光(CHL)。L-012主通過與羥?由和次氯酸鹽反應(yīng)產(chǎn)?CHL。L-012可以?于研究復(fù)雜?物系統(tǒng)的ROS?成以及ROS在各種疾病發(fā)病機制中的作?。?MaterTodayBio.2024Jul22:28:101163.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].ImadaI,etal.AnalysisofreactiveoxygenspeciesgeneratedbyneutrophilsusingachemiluminescenceprobeL-012[J].Analyticalbiochemistry,1999,271(1):53-58.[2].ZielonkaJ,etal.OntheuseofL-012,aluminol-basedchemiluminescentprobe,fordetectingsuperoxideandidentifyinginhibitorsofNADPHoxidase:areevaluation.FreeRadicBiolMed.2013;65:1310-1314.[3].KiellandA,etal.InvivoimagingofreactiveoxygenandnitrogenspeciesininflammationusingtheluminescentprobeL-012.FreeRadicBiolMed.2009;47(6):760-766.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-537003