Mequinol-Standard-生命科學試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEMequinol(Standard)Cat.No.:HY-30270RCASNo.:150-76-5分子式:C?H?O?分子量:124.14作用靶點:HSP;EstrogenReceptor/ERR作用通路:CellCycle/DNADamage;MetabolicEnzyme/Protease;VitaminDRelated/NuclearReceptor儲存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Mequinol(Standard)是Mequinol的分析標準品。本產品用于研究及分析應用。Mequinol(4-Methoxyphenol)是Mercurialis的生物活性成分之一，主要用于皮膚褪色[1]。Mequinol是一種抗氧化劑，與其他酚類抗氧化劑組合時，對致癌作用具有相加/協同作用。Mequinol還促進hERα依賴性伴侶蛋白產生，具有潛在雌激素活性。IC50&Target HSP27,GRP94,GRP78[2]REFERENCESCallenderVD,etal.Postinflammatoryhyperpigmentation:etiologicandtherapeuticconsiderations.AmJClinDermatol.2011Apr1;12(2):87-99.KitaK,etal.Increaseinthelevelsofchaperoneproteinsbyexposuretobeta-estradiol,bisphenolAand4-methoxyphenolinhumancellstransfectedwithestrogenreceptoralphacDNA.ToxicolInVitro.2009Jun;23(4):728-35.HiroseM,etal.CarcinogenicityofantioxidantsBHA,caffeicacid,sesamol,4-methoxyphenolandcatecholatlowdoses,eitheraloneorincombination,andmodulationoftheireffectsinaratmedium-termmulti-organcarcinogenesismodel.Carcinogenesis.1998Jan;19(1):207-12.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021-5