minus-Epigallocatechin-Gallate-d4-EGCG-d-sub-4-sub-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemE(-)-EpigallocatechinGallate-d4Cat.No.:HY-13653S1Synonyms:EGCG-d4;EpigallocatecholGallate-d4分?式:C??H??D?O??分?量:462.4作?靶點(diǎn):Isotope-LabeledCompounds;Apoptosis作?通路:Others;Apoptosis儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性(-)-EpigallocatechinGallate-d4(EGCG-d4;EpigallocatecholGallate-d4)氚代標(biāo)記的(-)-EpigallocatechinGallate(HY-13653)。(-)-EpigallocatechinGallatesulfate(EGCG)綠茶中的?種主多酚，可抑制細(xì)胞增殖并誘導(dǎo)細(xì)胞凋亡。(-)-EpigallocatechinGallatesulfate可抑制?氨酸脫氫酶1/2(GDH1/2,GLUD1/2)的活性。(-)-EpigallocatechinGallatesulfate對(duì)結(jié)直腸癌、髓性??病、甲狀腺癌等多種癌癥具有有效的抗癌、抗氧化和抗炎特性[1][2][3][4]。REFERENCES[1].DeAmicisF,etal.EpigallocatechingallateinhibitsgrowthandEpithelial-to-MesenchymalTransitioninhumanthyroidcarcinomacelllines.JCellPhysiol.2013Apr1.[2].PeetersTH,etal.Isocitratedehydrogenase1-mutatedcancersaresensitivetothegreenteapolyphenolepigallocatechin-3-gallate.CancerMetab.2019May20;7:4.[3].JinH,etal.EpigallocatechingallateinhibitstheproliferationofcolorectalcancercellsbyregulatingNotchsignaling.OncoTargetsTher.2013;6:145-53.[4].TsukasaTominari;Epigallocatechingallate(EGCG)suppresseslipopolysaccharide-inducedinflammatoryboneresorption,andprotectsagainstalveolarbonelossinmice.FEBSOpenBio.2015Jun12;5:522-7.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792