重組人成纖維細胞生長因子 8作用機制 - Medchemexpress - MCE中國

1、Product Data SheetRecombinant Human Fibroblast Growth Factor 8Cat. No.: HY-P7346Synonyms: rHuFGF-8; FGF-8; AIGF; HBGF-8Species: HumanSource: E. coliAccession: P55075Gene ID: 2253Molecular Weight: Approximately 22.5 kDaPROPERTIESAA SequenceMQ V T V Q S S P N F T Q H V R E Q S L V T D Q L S R R L I R

2、T Y Q L Y S R T S A E T G L Y I C MN K K G K L I A K S N G K G K D C V F T E I V L E N N Y T A L G K H V Q V L A N K R I N A M A E D G D P F A K L I V E T D T F G S R V R V R GQ N A K Y E GW Y M A F T R K G R P R K G S K T R Q H Q R E V H F M K R L P R GH H T T E Q S L R F E F L N Y P P F T R S L R

3、G S Q R T WA P E P RBiological Activity The ED50 is 2 105 units/mg.Appearance Lyophilized powder.Formulation Lyophilized after extensive dialysis against PBS.Endotoxin Level 0.2 EU/g, determined by LAL method.Reconsititution Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8 (

4、rHuFGF-8) to 100 g/mL using ddH2O.Storage & Stability Lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) is stored at -20C. After reconstitution, it isstable at 4C for 2 weeks or -20C for longer. It is recommended to freeze aliquots at -20C or -80C for extended storage.Shipping Room

5、 temperature in continental US; may vary elsewhere.DESCRIPTIONBackground Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumortypes. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death1.REFERENCESPage 1 of 2 www.MedChemE1. Harpain F, et al. FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer. J Cancer Res Clin Oncol. 2019 Jan;145(1):77-86.McePdfHeightCaution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792;F