GRGDSP-TFA - Integrin 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEGRGDSP TFACat. No.: HY-P0290A分式: CHFNO分量: 701.61Sequence: Gly-Arg-Gly-Asp-Ser-ProSequence Shortening: GRGDSP作靶點: Integrin作通路: Cytoskeleton儲存式: Powder -80C 2 years-20C 1 yearIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 H2O : 125

2、 mg/mL (178.16 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.4253 mL 7.1265 mL 14.2529 mL5 mM 0.2851 mL 1.4253 mL 2.8506 mL10 mM 0.1425 mL 0.7126 mL 1.4253 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 GRGDSP (TFA)種整聯(lián)蛋 (integrin) 抑制劑。IC50 & Target In

3、tegrin 1.體外研究It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor whichincludes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEthe adherence of tumor cells t

4、o endothelial cells of blood vessels and limit its metastasis 1. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widelytogether with other RGD peptides in integrin research. GRGDSP can be used to modify the surface ofcardiovascular implants s

5、uch as vascular grafts to promote endothelialization 2.REFERENCES1. Qian J, et al. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization fortreating hepatocellular carcinoma in a rat model. World J Gastroenterol. 2016 Jun 7;22(21):5042-9.2. Patel S, et al. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J Biomed Mater Res A.2007 Nov;83(2):423-33.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3