3-4-Dihydroxyflavone-3-4-DHF-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE3,4-DihydroxyflavoneCat. No.: HY-111802CAS No.: 14919-49-4Synonyms: 3,4-DHF分式: CHO分量: 254.24作靶點: Influenza Virus作通路: Anti-infection儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 155 mg/mL

2、(609.66 mM)H2O : 0.1 mg/mL (insoluble)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.9333 mL 19.6665 mL 39.3329 mL5 mM 0.7867 mL 3.9333 mL 7.8666 mL10 mM 0.3933 mL 1.9666 mL 3.9333 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 3,4-

3、Dihydroxyflavone (3,4-DHF)種具有服活性的酮類化合物，具有抗病毒活性，如，甲型流感病毒(Influenza A virus)。體內(nèi)研究3,4-Dihydroxyflavone (3,4-DHF; PO, 1 mg/kg per 30 L, daily, 5 days) significantly decreases virus titers1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEand pathological changes in the lung and reduced body weight loss an

4、d death 1.Animal Model: 3,4-Dihydroxyflavone (3,4-DHF; PO, 1 mg/kg per 30 L, daily, 5 days) significantlydecreases virus titers and pathological changes in the lung and reduced body weight lossand death 1.Dosage: 1 mg/kg per 30 L.Administration: Oral administration daily for 5 days.Result: Significa

5、ntly decreased virus titers and pathological changes in the lung and reducedbody weight loss and death.REFERENCES1. Hossain MK, et al. Antiviral activity of 3,4-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58