N-Acetyltyramine-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?Agonists?ScreeningLibrarieswww.MedChemEN-AcetyltyramineCat.No.:HY-120504CASNo.:1202-66-0分?式:C??H??NO?分?量:179.22作?靶點(diǎn):Bacterial作?通路:Anti-infection儲(chǔ)存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:100mg/mL(557.97mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM5.5797mL27.8987mL55.7973mL5mM1.1159mL5.5797mL11.1595mL10mM0.5580mL2.7899mL5.5797mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存?式和期限。BIOLOGICALACTIVITY?物活性N-Acetyltyramine溶藻弧M3-10產(chǎn)?的群體感應(yīng)抑制劑(QSI)化合物。N-Acetyltyramine能抑制C.violaceumATCC12472的群體感應(yīng)(QS)。N-Acetyltyramine逆轉(zhuǎn)阿霉素耐藥??病P388細(xì)胞的耐藥性。體外研究N-AcetyltyramineenhancescytotoxicityofdoxorubicininresistantP388murineleukemiacellswithanIC50valueof0.13μg/mlcomparedwithanIC50valueof0.48μg/mlfordoxorubicinalone[2].REFERENCES1/2MasterofSmallMolecules—您?邊的抑制劑?師www.MedChemE[1].ReinaJC,etal.AQuorum-SensingInhibitorStrainofVibrioalginolyticusBlocksQs-ControlledPhenotypesinChromobacteriumviolaceumandPseudomonasaeruginosa.MarDrugs.2019;17(9):494.Published2019Aug24.[2].KunimotoS,etal.ReversalofresistancebyN-acetyltyramineorN-acetyl-2-phenylethylamineindoxorubicin-resistantleukemiaP388cells.JAntibiot(Tokyo).1987;40(11):1651-1652.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792a