Menthofuran-DataSheet-生命科學試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEMenthofuranCat.No.:HY-N9484CASNo.:494-90-6分?式:C??H??O分?量:150.22作?靶點:DrugMetabolite作?通路:MetabolicEnzyme/Protease儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性數(shù)據(jù)體外實驗氘代氯仿:125mg/mL(832.11mM;Needultrasonic)DMSO:100mg/mL(665.69mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲備液1mM6.6569mL33.2845mL66.5690mL5mM1.3314mL6.6569mL13.3138mL10mM0.6657mL3.3285mL6.6569mL體內(nèi)實驗請根據(jù)您的實驗動物和給藥?式選擇適當?shù)娜芙?案。以下溶解?案都請先按照InVitro?式配制澄的儲備液，再依次添加助溶劑：(為保證實驗結(jié)果的可靠性，澄的儲備液可以根據(jù)儲存條件，適當保存；體內(nèi)實驗的?作液，建議您現(xiàn)?現(xiàn)配，當天使?；以下溶劑前顯?的百分?指該溶劑在您配制終溶液中的體積占?；如在配制過程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過加熱和/或超聲的?式助溶)1.請依序添加每種溶劑：10%DMSO>>40%PEG300>>5%Tween-80>>45%salineSolubility:≥2.5mg/mL(16.64mM);Clearsolution2.請依序添加每種溶劑：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2.5mg/mL(16.64mM);Clearsolution3.請依序添加每種溶劑：10%DMSO>>90%cornoilSolubility:≥2.5mg/mL(16.64mM);Clearsolution1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEBIOLOGICALACTIVITY?物活性Menthofuran(R)-(+)-Pulegone的毒性代謝物。Menthofuran通過控制下游單萜還原酶來調(diào)控薄荷精油的?物合成。REFERENCES[1].GordonWP,etal.Themetabolismoftheabortifacientterpene,(R)-(+)-pulegone,toaproximatetoxin,menthofuran.DrugMetabDispos.1987Sep-Oct;15(5):589-94.[2].MahmoudSS,etal.Menthofuranregulatesessentialoilbiosynthesisinpeppermintbycontrollingadownstreammonoterpenereductase.ProcNatlAcadSciUSA.2003Nov25;100(24):14481-6.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-58955