Mexiletine-d6-hydrochloride-KOE-1173-d6-hydrochloride-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEMexiletine-d6hydrochlorideCat.No.:HY-A0093SCASNo.:1329835-60-0Synonyms:KOE-1173-d6hydrochloride分?式:C??H??D?ClNO分?量:221.76作?靶點(diǎn):SodiumChannel作?通路:MembraneTransporter/IonChannel儲(chǔ)存?式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:50mg/mL(225.47mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM4.5094mL22.5469mL45.0938mL5mM0.9019mL4.5094mL9.0188mL10mM0.4509mL2.2547mL4.5094mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性Mexiletine-d6hydrochloride(KOE-1173-d6hydrochloride)Mexiletinehydrochloride(KOE-1173hydrochloride)的氘代物。Mexiletinehydrochloride，?種ClassIB類抗?律失?；衔铮c離?通道(voltage-gatedsodiumchannel)阻斷劑。REFERENCES1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemE[1].MoriK,etal.InhibitoryeffectsofclassIandIVantiarrhythmicdrugsontheNa+-activatedK+channelcurrentinguineapigventricularcells.NaunynSchmiedebergsArchPharmacol.1998Dec;358(6):641-8.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-5