2-Phospho-L-ascorbic-acid-trisodium-salt-L-Ascorbic-acid-2-phosphate-trisodium-salt-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE2-Phospho-L-ascorbic acid trisodium saltCat. No.: HY-107837CAS No.: 66170-10-3Synonyms: L-Ascorbic acid 2-phosphate trisodium salt; Sodium L-ascorbyl-2-phosphate分式: CHNaOP分量: 322.05作靶點(diǎn): c-Met/HGFR; Reactive Oxygen Species作通路: Pr

2、otein Tyrosine Kinase/RTK; Immunology/Inflammation;Metabolic Enzyme/Protease; NF-B儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O : 150 mg/mL (465.77 mM; Need ultrasonic)DMSO : 1 mg/mL (insoluble or slightly soluble)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1

3、mM 3.1051 mL 15.5255 mL 31.0511 mL5 mM 0.6210 mL 3.1051 mL 6.2102 mL10 mM 0.3105 mL 1.5526 mL 3.1051 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 2-Phospho-L-ascorbic acid trisodium salt種抗氧化劑，能夠促進(jìn)肝細(xì)胞長因 (HGF) 的產(chǎn)。體外研究2-Phospho-L-ascorbic acid (Asc 2-P) acts as an antioxidant an

4、d a stimulator of hepatocyte growth factor1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE(HGF) production. 2-Phospho-L-ascorbic acid is a stable derivative of L-ascorbic acid (AA) and possessessimilar biological properties as AA. AA and Asc-2P regulate a number of biological processes 1. When 2-Ph

5、ospho-L-ascorbic acid is added together with DHT, DHT-induced DKK-1 mRNA expression in DPCs issignificantly attenuated. It is also found that DKK-1 promoter activity is increased by DHT treatmen. When 2-Phospho-L-ascorbic acid is added together with DHT, DHT-induced activation of luciferase activity

6、 issignificantly repressed 2.REFERENCES1. Bae SH, et al. L-ascorbic acid 2-phosphate and fibroblast growth factor-2 treatment maintains differentiation potential in bone marrow-derived mesenchymal stem cells through expression of hepatocyte growth factor. Growth Factors. 2015 Apr;33(2):71-8.2. Kwack MH, et al. L-ascorbic acid 2-phosphate represses the dihydrotestosterone-induced dickkopf-1 expression in human baldingdermal papilla cells. Exp Dermatol. 2010 Dec;19(12):1110-2.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use onl