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骨轉(zhuǎn)移性乳腺癌GeneralinformationName:WUChunHongAge:40ySex:FemaleDateofadmission:February9th,2011Dateofdischarge:April23th,20112骨轉(zhuǎn)移性乳腺癌ChiefcomplaintShegothypoesthesiaoflowerlimbsandinabilitytowalkformorethanamonth3骨轉(zhuǎn)移性乳腺癌HistoryofpresentillnessThepatientfelt

painonthebackbynoobviousincentivesinJune2010Thepainwastingling,especiallyinnight-timeThepatienttookorallytraditionalChinesemedicine,buthadnottangibleeffects4骨轉(zhuǎn)移性乳腺癌Past,

Personal&FamilyHistoryNo

hepatitis,hypertension,ordiabetesNosmoking,alcoholordrugabuseNoinheriteddiseasesNohistoryofdrugallergyNormalmenstruation5骨轉(zhuǎn)移性乳腺癌ClinicalfindingsTheleftbreastpresentedwithdiffusederythemaandedema,

indurationaboutsizeof3.0cm*3.0cm6骨轉(zhuǎn)移性乳腺癌Ultrasoundexaminationa3cmleftbreastmassandanormalrightbreast7骨轉(zhuǎn)移性乳腺癌ThoracicMRIexamination

8骨轉(zhuǎn)移性乳腺癌Laboratoryexamination2011-02-091.HepaticfunctionsALT40U/LAST20U/LTBNormal3.TumormarkersCA19-9Normal2.Bloodroutinetest

Hb82g/L

RBC4.54×1012/L

WBC6.1×109/LPLT201×109/L10骨轉(zhuǎn)移性乳腺癌puncturebiopsyShereceivedultrasoundguidedbreastcoreneedlepuncturebiopsyPuncturetissuepathology:Theleftbreastinvasiveductalcarcinoma11骨轉(zhuǎn)移性乳腺癌Primarydiagnosis

Breastcancerwithbonemetastasis12骨轉(zhuǎn)移性乳腺癌TreatmentOnFebruary11,2011inorthopedicdepartment,ThePatientreceived"thesevenththoracictumorresectionandpediclescrewfixation"13骨轉(zhuǎn)移性乳腺癌HistologicalexaminationSevenththoracictumorswasidentifiedasmetastaticcarcinoma,andtheimmunohistochemistryresultsshowedthepossibilityofbreastcancerbonemetastasiswasverylarge14骨轉(zhuǎn)移性乳腺癌IMMUNOHISTOCHEMICALresultsER++PR++CerbB2-

CK20-EMA++,Ckpan+++,CK5/6-15骨轉(zhuǎn)移性乳腺癌TreatmentThepatientrecoveredwell,andthentransferredintoourdepartmentChemotherapytwotimesbeforeoperation:February23,2011March20,2011ThechemotherapyplanwasTEC16骨轉(zhuǎn)移性乳腺癌TreatmentAfterthe

chemotherapyThelesionsareaofleftbreastshowednoreduction17骨轉(zhuǎn)移性乳腺癌TreatmentModifiedradicalmastectomyonmarch31,2011BilateraloophorectomyOnthesameday18骨轉(zhuǎn)移性乳腺癌HistologicalexaminationTheleftbreastinvasiveductalcarcinomaThebasalresectionmarginoftumorwasclosetothesurroundingnormaltissueTheaxillarylymphnodesmetastasis(13/15)19骨轉(zhuǎn)移性乳腺癌ImmunohistochemicalER++PR++CerbB2-

E-cad+++,Ki6750%+,P53+,Ck5/6

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